Diabetes Care:睡眠和昼夜节律与糖尿病前期或2型糖尿病患者血糖相关

2019-05-18 xing.T 网络

由此可见,在该队列中,自我报告的短期和长期睡眠均与血糖的不良指标相关,短睡眠和轮班工作与较高的BMI相关。需要进一步研究使用客观的睡眠测量方法,以更好地描述糖尿病前期或T2D成人睡眠和血糖之间的关系。

睡眠障碍和昼夜节律紊乱(时差或轮班工作)与2型糖尿病(T2D)的血糖控制较差有关。这些研究结果是否适用于糖尿病前期的成年人尚未明确。近日,糖尿病领域权威杂志Diabetes Care上发表了一篇研究文章,研究人员假设自我报告的短睡眠、较差的睡眠质量和/或昼夜节律错位与糖尿病前期或最近诊断为未治疗T2D成人中较高的血糖、BMI和血压(BP)之间存在相关性。 

该研究队列包括962名年龄在20-65岁之间的超重/肥胖成人,他们为糖尿病前期患者或最近诊断为未治疗的T2D,并完成了2小时口服葡萄糖耐量试验和验证的睡眠问卷。研究人员使用回归模型评估睡眠和昼夜变量与血糖、BMI和BP的独立关联。

多民族队列男性占55%,平均±SD年龄为52.2±9.5岁,BMI为34.7±5.5 kg/m2。平均睡眠持续时间为6.6±1.3小时。据报道,睡眠质量差的个体占54%,阻塞性睡眠呼吸暂停的风险高达64%。HbA1c在报告<5或>8小时每晚睡眠的人中显著更高。睡眠持续时间>8h也与空腹血糖升高有关,而睡眠呢时间<6h则BMI更高。轮班工作也与较高的BMI有关。时差与较高的血压相关。 

由此可见,在该队列中,自我报告的短期和长期睡眠均与血糖的不良指标相关,短睡眠和轮班工作与较高的BMI相关。需要进一步研究使用客观的睡眠测量方法,以更好地描述糖尿病前期或T2D成人睡眠和血糖之间的关系。
 
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    2021-06-27 小小医者

    #睡眠##昼夜节律##糖尿病#复杂关系,可能因为节律紊乱,从而导致免疫,代谢和内分泌问题,从而引发糖尿病吧

    0

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createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Sat May 18 11:52:47 CST 2019, time=2019-05-18, status=1, ipAttribution=)]
    2019-05-18 gcwu82

    非常好值得学习借鉴

    0

  8. 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    2019-05-18 misszhang

    谢谢MedSci提供最新的资讯

    0

  9. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=650f104372, createdName=gcwu82, createdTime=Sat May 18 16:03:32 CST 2019, time=2019-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1042459, encodeId=501a104245957, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat May 18 14:31:00 CST 2019, time=2019-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=366393, encodeId=e28c3663933b, content=学习了,涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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    2019-05-18 王秀

    学习了,涨知识了!

    0

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