J Hypertens:正常血压人群早晨血压与亚临床靶器官损害之间的关系

2019-02-10 xing.T MedSci原创

由此可见,该研究的结果表明正常血压患者早晨血压的升高与左心室肥厚有关。早晨BP的家庭监测可能适合于检测异常的血压晨峰。

近日,高血压领域权威杂志Journal of Hypertension上发表了一篇研究文章,研究人员旨在调查孤立性升高的早晨血压(BP)是否与正常血压个体的亚临床靶器官损害有关。

该研究总共纳入了287名血压正常的个体进行横断面研究。每位参与者都进行了人体测量、血清生化评估、24小时动态血压监测、超声心动图和颈动脉超声检查。早晨BP和晨峰定义分别为:醒来后2小时内的平均血压,醒来后2小时内平均收缩压(SBP)与1小时内平均SBP(包括睡觉期间最低血压读数)之间的差异。

早晨BP升高的患病率为37.3%。早晨BP升高的个体左心室质量指数和峰值较高,24小时平均、白天和夜间SBP和舒张压、血压变异均较高(均P<0.05)。左心室质量指数与24小时、白天、夜间、早晨SBP和晨峰(Pearson相关系数分别为0.271、0.262、0.215、0.368和0.415;均P<0.05),24小时、白天和夜间SBP的标准差(Pearson相关系数分别为0.303、0.234和0.309)以及24小时和夜间SBP的变异系数(Pearson相关系数分别为0.253和0.271)相关。在多元回归分析中,晨峰与左心室质量指数的相关性最强。只有白天和早晨SBP可以区分早晨升高的峰值(≥35mmHg),曲线下面积分别为0.744和0.864(均P<0.01),早晨SBP最佳阈值为121.5mmHg。

由此可见,该研究的结果表明正常血压患者早晨血压的升高与左心室肥厚有关。早晨BP的家庭监测可能适合于检测异常的血压晨峰。

原始出处:


Ye, Runyu.et al.The association between morning blood pressure and subclinical target organ damage in the normotensive population. Journal of Hypertension. 2019.https://journals.lww.com/jhypertension/Abstract/publishahead/The_association_between_morning_blood_pressure_and.97270.aspx

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    2020-01-17 habb
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    2019-11-07 feather89
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    2019-02-10 jingjing

    大家一般关心疾病,但是亚临床更重要,这是疾病防控方向的前移,各类疾病都是这样。如亚临床甲减,亚临床心肌损伤,亚临床心衰等

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2078442, encodeId=dda120e844232, content=<a href='/topic/show?id=4d92999582c' target=_blank style='color:#2F92EE;'>#靶器官#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99958, encryptionId=4d92999582c, topicName=靶器官)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=19c567, createdName=habb, createdTime=Fri Jan 17 17:45:00 CST 2020, time=2020-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2039022, encodeId=43e620390228b, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Sun Dec 08 00:45:00 CST 2019, time=2019-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1727886, encodeId=57fa1e27886de, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Thu Nov 07 02:45:00 CST 2019, time=2019-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693912, encodeId=4a5916939124b, content=<a href='/topic/show?id=48a140299ae' target=_blank style='color:#2F92EE;'>#器官损害#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40299, encryptionId=48a140299ae, topicName=器官损害)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fdcd29484210, createdName=lujian, createdTime=Sat Oct 12 11:45:00 CST 2019, time=2019-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050229, encodeId=1ce810502296b, content=大家一般关心疾病,但是亚临床更重要,这是疾病防控方向的前移,各类疾病都是这样。如亚临床甲减,亚临床心肌损伤,亚临床心衰等, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=jingjing, createdTime=Sun Feb 10 21:45:00 CST 2019, time=2019-02-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=360344, encodeId=800036034403, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Sun Feb 10 19:49:31 CST 2019, time=2019-02-10, status=1, ipAttribution=)]
    2019-02-10 orangesking

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