Lancet:99例新冠肺炎患者流行病及临床特征研究

2020-02-15 MedSci MedSci原创

研究发现,男性2019-nCoV感染患者比例较高,可导致严重甚至致命的呼吸窘迫综合征,死亡患者的特征符合MuLBSTA模型

2019年12月,武汉发生了2019年新型冠状病毒(2019-ncov)相关的肺炎。近日研究人员对2019-nCoV肺炎的流行病学及临床特征进行了进一步研究。

2020年1月1日-2020年1月20日,武汉金银潭医院收治的经RT-PCR确诊的2019-nCoV肺炎患者参与研究。对患者的流行病学、人口学、临床和放射学特征及实验室数据进行分析,临床结果随访至2020年1月25日。

99名患者参与研究,其中49人(49%)存在武汉华南海鲜市场暴露史,患者平均年龄55.5岁,其中男性67人,女性32人。50人(51%)有基础慢病史。患者的临床特征包括发热(82例)、咳嗽(81例)、呼吸急促(31例)、肌肉痛(11例)、精神错乱(9例)、头痛(8例)、喉咙痛(5例)、流涕(4例)、胸痛(2例)、腹泻(2例)以及恶心呕吐(1例)。根据CT检查,74例(75%)患者证实双侧肺炎、14例(14%)显示多个斑点和毛玻璃状、1例(1%)伴有气胸。17(17%)患者出现急性呼吸窘迫综合征,其中11(11%)患者在短时间内病情恶化,因多器官衰竭死亡。

研究发现,男性2019-nCoV感染患者比例较高,可导致严重甚至致命的呼吸窘迫综合征,死亡患者的特征符合MuLBSTA模型。

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    2021-01-25 howi
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    2020-02-17 xugumin
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    2020-02-15 公卫新人

    新冠肺炎,疫情何时才能消失

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