Nature Medicine:NIH的意外研究结果:无需再纠结,低脂和低碳水随便挑一个!

2021-01-23 MedSci原创 MedSci原创

该研究结果拓宽了对限制饮食中低碳水或低脂肪饮食如何影响健康的理解。至少在短期内,两种饮食对身体都有好处。

最近,美国国立卫生研究院(NIH)的一项小型但高度对照的研究结果提示,相比于低碳水化合物而动物性食物为主的饮食,低脂肪而植物性食物为主的饮食每天吃的卡路里较少,但胰岛素和血糖水平较高。由美国国家糖尿病消化与肾脏疾病研究所(NIDDK)的研究人员领导的这项研究比较了两种饮食对热量摄入、激素水平、体重等的影响,相关结果发表在最新的《自然医学》(Nature Medicine)杂志上。

既往的认知一般都把高脂肪食物等同于热量摄入过多,而高碳水化合物食物则被认为会引起血糖和胰岛素的大幅波动从而增加饥饿感并导致暴饮暴食。该研究的主要作者,NIDDK高级研究员Kevin Hall博士说:"我们的研究旨在确定高碳水或高脂肪饮食是否会导致更高的热量摄入。"

研究人员将20名没有糖尿病的成年人安置在NIH临床中心的代谢临床研究室。参与者包括11名男性和9名女性,先接受为期两周的植物性低脂饮食或动物性低碳水饮食,紧接着再进行两周的交替饮食,共为期4周。其中,低脂饮食的碳水化合物含量很高,而低碳水化合物的饮食是高脂肪的。两种饮食都是最低限度的加工,并且有等量的非淀粉类蔬菜。除外一日三餐,参与者还可以选择零食,随心所欲不限吃的具体数量。

其中,植物性低脂饮食含10.3%的脂肪和75.2%的碳水化合物,而动物性低碳水饮食则含10%的碳水化合物和75.8%的脂肪。两种饮食都含有约14%的蛋白质,并且呈现给受试者的总热量是匹配的,但低碳水化合物饮食每克食物的热量是低脂肪饮食的两倍。

研究中的饮食:动物性低碳水饮食(左)和植物性低脂饮食(右)

结果显示,低脂饮食的人每天吃的热量比吃低碳水化合物饮食时少了550700卡路里。尽管卡路里摄入量差异较大,但参与者报告说,两种饮食在饥饿感、用餐享受或饱腹感方面没有差异。同时,参与者在两种饮食中都减轻了体重,但低脂饮食导致体脂显著下降。

"尽管吃了大量高血糖碳水化合物的食物引起血糖和胰岛素明显波动,但吃植物性低脂饮食的人却出现了热量摄入的显著减少和体脂降低,这对高碳水化合物饮食本身会导致人们暴饮暴食的观点提出了挑战。另一方面动物性低碳水化饮食尽管脂肪含量很高,但并没有导致体重增加。" Holl说。

这些研究结果表明,导致暴饮暴食和体重增加的因素比一个人饮食中碳水化合物或脂肪的含量更复杂。例如,Hall的实验室在2019年表明,与碳水化合物和脂肪匹配的最低加工饮食相比,高超加工食物的饮食会导致过度饮食和体重增加。 

研究人员指出,该研究并非想为减肥的人群提出饮食建议,如果参与者很想尝试减肥,结果可能会有所不同。在研究条件下为受试者准备并提供所有膳食,可能会导致结果难以在实验室外重复。不过,严格控制临床环境,确保了摄食量的客观测量和数据的准确性。

综上,该研究结果拓宽了对限制饮食中低碳水或低脂肪饮食如何影响健康的理解。至少在短期内,两种饮食对身体都有好处。虽然植物性低脂饮食有助于抑制食欲,但动物性低碳水饮食可以维持更低和更稳定的胰岛素和葡萄糖水平。至于这些差异是否会长期持续可能还需要进一步的研究。

参考文献:

Hall KD, Guo J, et al. Effect of a plant-based, low-fat diet versus an animal-based, ketogenic diet on ad libitum energy intake. Nat Med. 2021 Jan 21. doi: 10.1038/s41591-020-01209-1.

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    2022-01-07 jeanqiuqiu
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    2021-09-20 liye789132251
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    2021-07-18 kalseyzl
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    2021-03-28 ms2000001361349190

    在短期内,两种饮食对身体都有好处

    0

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    2021-01-25 宋威
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    2021-01-23 zb1235672

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