Eur Arch Otorhinolaryngol:永久先天性突发感官听力损失中挽救性地塞米松注射可能益处研究

2020-05-15 AlexYang MedSci原创

最近,有研究人员比较了起始治疗或者挽救性地塞米松注射(ITDI)对听力恢复水平的影响,并发现了永久性ISSNHL中挽救性ITDI治疗的预后因子。

最近,有研究人员比较了起始治疗或者挽救性地塞米松注射(ITDI)对听力恢复水平的影响,并发现了永久性ISSNHL中挽救性ITDI治疗的预后因子。

研究人员回顾性的调查了115名永久性ISSNHL患者。研究发现,有效听力恢复比例在初始治疗组中为10.4%(12/115),而在挽救性治疗组中为20.4%(21/103)。差异具有统计学显著性(p=0.041)。挽救性治疗前PTA、糖尿病和症状持续时间均为初始治疗难治永久性ISSNHL挽救性ITDI治疗效果的影响因子,风险比分别为1.169(95%CI,1.088-1.256)、0.069(95%CI,0.005-0.889)和9.242(95%CI,1.079-79.146)。

最后,研究人员指出,挽救性治疗应该考虑应用于永久性ISSNHL,且ITSI治疗应该是挽救性治疗的有效方式。

原始出处:

Choi JW, Lee CK, Kim SB et al. Potential benefits of salvage intratympanic dexamethasone injection in profound idiopathic sudden sensorineural hearing loss. Eur Arch Otorhinolaryngol. 15 April 2020.

 

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    2020-05-17 ysjykql
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    2020-05-17 huirong
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    2020-05-16 1902498648_44512810

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