JCEM:中国2型糖尿病患者冠心病和脑卒中患病率的地域差异

2018-07-04 xing.T MedSci原创

由此可见,中国T2DM患者CHD、卒中和两者合并的风险存在较大差异,其中东北和北方地区风险最高。

中国一般人群中心血管疾病的患病率和死亡率存在较大的区域差异。目前尚不确定中国2型糖尿病(T2DM)患者中这些疾病的患病率是否存在地域差异。近日,内分泌和代谢性疾病领域权威杂志Journal of Clinical Endocrinology & Metabolism上针对这一问题发表了一篇研究文章。

研究人员分析了2012年从中国国家HbA1c监测系统中检索到的219522例中国T2DM患者的数据,利用2010年中国人口分布标准化了30个省和7个地区的冠心病(CHD)、卒中和合并患病率。研究人员进行多变量logistic回归以获得CHD、卒中和两者合并的省/地区的比值比(OR)和置信区间(CI)。

CHD、卒中和两者合并的年龄和性别标准化患病率分别为4.59%(95%CI为4.58-4.60)、1.79%(1.79-1.80)和5.85%(5.84-5.86),而中国一般人群中CHD为0.60%,卒中为0.80%和两者合并为1.37%。调整传统危险因素后,东北地区CHD、卒中和两者合并的风险最高,北方在七个地区中CHD、卒中和两者合并的风险排名第二,均高于其他任何地区(均为P值<0.05)。东北与西南相比,CHD、卒中和两者合并的OR值分别为2.60(2.35-2.88)、2.49(2.15-2.88)和2.61(2.38-2.86)。

由此可见,中国T2DM患者CHD、卒中和两者合并的风险存在较大差异,其中东北和北方地区风险最高。

原始出处:


Yuanjun Lyu,et al.Regional differences in the prevalence of coronary heart disease and stroke in patients with type 2 diabetes in China.J Clin Endocrinol Metab. 2018.https://doi.org/10.1210/jc.2018-00422

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    2018-11-20 仁者大医
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    2019-06-02 achengzhao
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    2018-07-09 大爰

    学习了谢谢分享!!

    0

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    2018-07-08 Sometimes1575

    哈哈哈哈哈哈

    0

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    2018-07-04 1201e5c5m39暂无昵称

    学习了

    0

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    2018-07-04 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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