JAHA:缺血性心肌病患者冠状动脉旁路移植术的早期和中期结局

2019-05-10 xing.T 网络

由此可见,缺血性心肌病患者冠状动脉旁路移植术与较高的早期复合结局相关。然而,5年生存率良好。左心室功能缺乏改善是晚期死亡率的强预测因子。

许多观察性研究和试验表明,冠状动脉旁路移植术可改善缺血性心肌病患者的生存率。但是,这些结果是基于发达国家的数据。社会经济状况不佳、医疗保健服务缺乏统一性、风险状况不同以及获得最佳医疗服务的可负担性是导致这些研究结论与印度患者不一致的因素。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,该研究招募了一百六十二名患有严重左心室功能不全(射血分数≤35%)的患者,他们在2009年至2017年接受了冠状动脉旁路移植术。

研究人群的平均年龄为58.67±9.70岁。手术死亡率为11.62%。卒中和围手术期心肌梗死的30天/住院复合结局为5.8%。 1年生存率为86.6%,5年生存率为79.9%。五年无事件生存率为49.3%。平均射血分数从30.7±4.08%(范围18-35)提高到39.9±8.3%(范围24-60)。左心室功能缺乏改善是晚期死亡率的强预测因子(风险比为21.41;95%CI为4.33-105.95)。尽管非体外循环CABG的早期结局有改善的趋势,但非体外循环组和体外循坏组5年生存率相似(分别为73.4% vs. 78.9%; P值为0.356)。

由此可见,缺血性心肌病患者冠状动脉旁路移植术与较高的早期复合结局相关。然而,5年生存率良好。左心室功能缺乏改善是晚期死亡率的强预测因子。

原始出处:

Rajesh Jose.et al.Early and Mid‐Term Outcomes of Patients Undergoing Coronary Artery Bypass Grafting in Ischemic Cardiomyopathy.JAHA.2019.https://www.ahajournals.org/doi/full/10.1161/JAHA.118.010225

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    2020-04-19 cy0324
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    2019-05-12 1ddf0692m34(暂无匿称)

    学习了,谢谢分享

    0

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    2019-05-12 医者仁心5538

    学习了

    0

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    2019-05-12 zhaohui6731
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