J Drugs Dermatol:激光联合口服避孕药治疗多囊卵巢综合征所致的多毛症

2021-08-22 MedSci原创 MedSci原创

据估计,多毛症影响了10%-20%的女性,造成了严重的心理伤害和社交尴尬。多囊卵巢综合征(PCOS)是导致女性多毛症的一个主要原因。

据估计,多毛症影响了10%-20%的女性,造成了严重的心理伤害和社交尴尬。多囊卵巢综合征(PCOS)是导致女性多毛症的一个主要原因。

发表于J Drugs Dermatol的一项随机研究评估了在激光脱毛的基础上增加联合口服避孕药(COCs)或二甲双胍对PCOS患者生活质量的影响。

研究纳入了150名诊断为多毛症的PCOS患者,随机分为三组:第一组仅接受激光脱毛,第二组接受二甲双胍和激光脱毛,第三组接受COCs和激光脱毛。按照每月6次、3个月和6个月后再进行两次治疗的方案,所有患者都使用了波长为810纳米的二极管激光器进行脱毛。使用视觉模拟量表(VAS)和皮肤病生活质量指数(DLQI)以及特定调查问卷(多毛症生活质量指数;HLQI)对患者进行评估。

结果显示,与治疗前相比,所有患者在治疗后的两项质量指数(DLQI和HLQI)都有明显改善。与第2组和第1组相比,第3组的改善更明显。在3个月和6个月时,第3组的DLQI和HLQI与基线相比没有明显的改善。另一方面,在三个月时,第2组患者的DLQI和HLQI的得分都明显恶化,随后在六个月时又有改善。最后,第1组患者在3个月时表现出恶化,而在6个月时明显恶化。

综上,该研究结果表明,激光脱毛联合COCs可更有效的治疗多毛症,患者的QOL得到明显改善,并且维持得更好。

原始出处:

Nevine Dorgham, et al., Adding Combined Oral Contraceptives or Metformin to Laser Treatment in Polycystic Ovarian Syndrome Hirsute Patients. J Drugs Dermatol. 2021 Mar 1;20(3):302-306. doi: 10.36849/JDD.5652.

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    2021-09-01 wangbingxhy
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time=2021-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1010441, encodeId=af5d1010441e9, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=435f5579553, createdName=ms7000001545202350, createdTime=Sun Aug 22 23:47:33 CST 2021, time=2021-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1010389, encodeId=2a731010389e3, content=<a href='/topic/show?id=800d4315123' target=_blank style='color:#2F92EE;'>#多囊卵巢综合征#</a>引发多毛症,与激素水平有关?反过来,这对<a href='/topic/show?id=15098523e34' target=_blank style='color:#2F92EE;'>#脱发#</a>治疗是否具有启示作用?, beContent=null, objectType=article, channel=null, level=null, likeNumber=194, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43151, encryptionId=800d4315123, topicName=多囊卵巢综合征), TopicDto(id=85237, 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  5. 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time=2021-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1010441, encodeId=af5d1010441e9, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=435f5579553, createdName=ms7000001545202350, createdTime=Sun Aug 22 23:47:33 CST 2021, time=2021-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1010389, encodeId=2a731010389e3, content=<a href='/topic/show?id=800d4315123' target=_blank style='color:#2F92EE;'>#多囊卵巢综合征#</a>引发多毛症,与激素水平有关?反过来,这对<a href='/topic/show?id=15098523e34' target=_blank style='color:#2F92EE;'>#脱发#</a>治疗是否具有启示作用?, beContent=null, objectType=article, channel=null, level=null, likeNumber=194, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43151, encryptionId=800d4315123, topicName=多囊卵巢综合征), TopicDto(id=85237, encryptionId=15098523e34, topicName=脱发)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=病毒猎手, createdTime=Sun Aug 22 21:13:23 CST 2021, time=2021-08-22, status=1, ipAttribution=)]
    2021-08-24 oliver169
  6. 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  7. 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time=2021-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1010441, encodeId=af5d1010441e9, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=435f5579553, createdName=ms7000001545202350, createdTime=Sun Aug 22 23:47:33 CST 2021, time=2021-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1010389, encodeId=2a731010389e3, content=<a href='/topic/show?id=800d4315123' target=_blank style='color:#2F92EE;'>#多囊卵巢综合征#</a>引发多毛症,与激素水平有关?反过来,这对<a href='/topic/show?id=15098523e34' target=_blank style='color:#2F92EE;'>#脱发#</a>治疗是否具有启示作用?, beContent=null, objectType=article, channel=null, level=null, likeNumber=194, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43151, encryptionId=800d4315123, topicName=多囊卵巢综合征), TopicDto(id=85237, 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  8. 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    2021-08-22 ms7000001545202350

    学习了

    0

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time=2021-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1010441, encodeId=af5d1010441e9, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=435f5579553, createdName=ms7000001545202350, createdTime=Sun Aug 22 23:47:33 CST 2021, time=2021-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1010389, encodeId=2a731010389e3, content=<a href='/topic/show?id=800d4315123' target=_blank style='color:#2F92EE;'>#多囊卵巢综合征#</a>引发多毛症,与激素水平有关?反过来,这对<a href='/topic/show?id=15098523e34' target=_blank style='color:#2F92EE;'>#脱发#</a>治疗是否具有启示作用?, beContent=null, objectType=article, channel=null, level=null, likeNumber=194, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43151, encryptionId=800d4315123, topicName=多囊卵巢综合征), TopicDto(id=85237, 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    2021-08-22 病毒猎手

    #多囊卵巢综合征#引发多毛症,与激素水平有关?反过来,这对#脱发#治疗是否具有启示作用?

    0

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