JAHA:心率变异性指数可预测房颤患者的心血管死亡率

2020-07-28 MedSci原创 MedSci原创

AF患者单次5分钟ECG记录中测得的HRV指数是心血管疾病死亡率的独立预测指标。AF患者的HRV分析可能是进一步进行风险分层以指导患者治疗较有价值的工具。

心率变异性(HRV)受损与窦性心律个体死亡率增加有关。但是,心房颤动(AF)患者HRV尚未得到系统评估。近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员假设HRV可以预测AF患者的心血管死亡。

从多中心前瞻性瑞士房颤(Swiss-AF)队列研究中,研究人员纳入了1922例窦性心律或AF患者。在基线时获得了5分钟的静息心电图记录,并计算了HRV的标准参数(HRV三角指数、正常至正常间隔的SD、连续的正常至正常间隔的均方差的平方根和平均心率)。在随访期间,终点委员会对每个死因进行了裁决。

平均随访时间为2.6±1.0年,143例(7.4%)患者死亡;92例死亡归因于心血管原因。在包含多个协变量(年龄、性别、体重指数、吸烟状况、糖尿病史、高血压史、卒中/短暂性脑缺血发作史、心肌梗死史、抗心律失常药物(包括β受体阻滞剂、口服抗凝药) )的Cox回归模型中,降低的HRV指数≤中位数(14.29),而非其他HRV参数,与心血管死亡(风险比为1.7;95%CI为1.1–2.6;P=0.01)和全因死亡(风险比为1.42;95%CI为1.02-1.98;P=0.04)风险增加相关。

由此可见,AF患者单次5分钟ECG记录中测得的HRV指数是心血管疾病死亡率的独立预测指标。AF患者的HRV分析可能是进一步进行风险分层以指导患者治疗较有价值的工具。

原始出处:

Peter Hämmerle.et al.Heart Rate Variability Triangular Index as a Predictor of Cardiovascular Mortality in Patients With Atrial Fibrillation.J AM HEART ASSOC.2020.https://www.ahajournals.org/doi/10.1161/JAHA.120.016075

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createdName=tainyxixixi, createdTime=Tue Jul 28 23:06:55 CST 2020, time=2020-07-28, status=1, ipAttribution=)]
    2020-07-29 12064aa6m34(暂无昵称)

    学习了

    0

  8. 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level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Wed Jul 29 00:14:42 CST 2020, time=2020-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=804977, encodeId=69d88049e7f6, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d5142645505, createdName=619103330, createdTime=Tue Jul 28 23:29:52 CST 2020, time=2020-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=804972, encodeId=dc398049e25e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=53dd2037011, createdName=tainyxixixi, createdTime=Tue Jul 28 23:06:55 CST 2020, time=2020-07-28, status=1, ipAttribution=)]
    2020-07-29 心介

    房颤,临床上碰到很多哦

    0

  9. 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level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Wed Jul 29 00:14:42 CST 2020, time=2020-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=804977, encodeId=69d88049e7f6, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d5142645505, createdName=619103330, createdTime=Tue Jul 28 23:29:52 CST 2020, time=2020-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=804972, encodeId=dc398049e25e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=53dd2037011, createdName=tainyxixixi, createdTime=Tue Jul 28 23:06:55 CST 2020, time=2020-07-28, status=1, ipAttribution=)]
    2020-07-28 619103330

    不错

    0

  10. 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level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Wed Jul 29 00:14:42 CST 2020, time=2020-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=804977, encodeId=69d88049e7f6, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d5142645505, createdName=619103330, createdTime=Tue Jul 28 23:29:52 CST 2020, time=2020-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=804972, encodeId=dc398049e25e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=53dd2037011, createdName=tainyxixixi, createdTime=Tue Jul 28 23:06:55 CST 2020, time=2020-07-28, status=1, ipAttribution=)]
    2020-07-28 tainyxixixi

    学习了

    0

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