JACC:早发型冠心病的远期进展研究

2019-10-18 不详 MedSci原创

早发冠心病(CAD)的远期发展规律尚不清楚。本研究的目的旨在描述年轻患者冠脉粥样硬化的发展规律和危险因素。本研究纳入分析了年龄≤45岁的急性或稳定梗阻性CAD患者,主要终点事件是全因死亡、心梗、需要冠状动脉血运重建的难治性心绞痛和缺血性中风。最终共纳入了880例早发CAD患者,平均年龄为 40.1±5.7岁,在基线水平时,91.2%的患者接受了冠脉血运重建,主要是由于急性心梗(78.8%)。经过超

早发冠心病(CAD)的远期发展规律尚不清楚。本研究的目的旨在描述年轻患者冠脉粥样硬化的发展规律和危险因素。

本研究纳入分析了年龄≤45岁的急性或稳定梗阻性CAD患者,主要终点事件是全因死亡、心梗、需要冠状动脉血运重建的难治性心绞痛和缺血性中风。最终共纳入了880例早发CAD患者,平均年龄为 40.1±5.7岁,在基线水平时,91.2%的患者接受了冠脉血运重建,主要是由于急性心梗(78.8%)。经过超过20年时间的随访,三分之一的患者发生了399起缺血性事件,且36%的患者至少有一次复发。心梗是最常见的复发事件,主要与新发冠脉损伤相关。全因死亡事件(6.3%)发生的平均时间是8.4年,民族血统、炎症疾病和持续性抽烟是最强的复发危险因素。

研究结果显示,早发型冠心病是一种进展性疾病,不良事件复发率和死亡率较高。

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    2021-01-20 147e4706m08暂无昵称

    学习了

    0

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    2020-04-19 hbwxf
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    2019-10-21 ShawYuan

    厉害了

    0

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    2019-10-18 天地飞扬

    学习了,谢谢分享

    0

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    2019-10-18 苏小雨

    非常有用,对我的文章有帮助

    0

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    2019-10-18 苏小雨

    学习了不错

    0

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历史数据显示未接受治疗的主动脉瓣狭窄(AS)患者的生存率低主要局限于严重AS患者。本研究的目的旨在评估所有AS类型患者的预后。本研究纳入分析了测量过主动脉瓣流速和压差的122809名男性患者(平均年龄61±17岁)和118494名女性患者(62±19岁),并排除之前接受过主动脉瓣干预治疗的患者。最终,共有16129名患者(6.7%)、3315名(1.4%)和6383名(2.6%)患者分别为轻度、中