Eur Heart J:院外心脏骤停的体外心肺复苏

2019-11-03 xing.T MedSci原创

由此可见,在基于人群的登记中,有4%的OHCA接受了体外CPR治疗,但与医院生存率提高无关。早期植入ECMO可能会改善患者结局。初始心律和ROSC可能有助于选择进行体外CPR的患者。

尽管常规复苏常用于无自发性循环(ROSC)恢复的院外心脏骤停(OHCA),但预后差。为了改善患者预后,越来越多地将体外膜氧合(ECMO)添加到心肺复苏(extracorporeal-CPR)中。

近日,心血管领域权威杂志Eur Heart J上发表了一篇研究文章,研究人员分析了2011年5月至2018年1月期间巴黎地区前瞻性登记中心13191名OHCA患者的资料,比较了进行或没有进行体外CPR的患者出院时的生存率,并确定与接受体外CPR的患者的生存相关的因素。

525例接受体外CPR的患者的生存率为8%,而12666例接受常规CPR的患者的生存率为9%(P=0.91)。通过调整后的多元分析,体外CPR与医院生存率无关[比值比(OR)为1.3; 95%置信区间(95%CI)为0.8-2.1;P=0.24]。通过条件logistic回归并与倾向得分(包括年龄、性别、在家中发生的情况、旁观者的心肺复苏术、初始心律、发作至心肺复苏术的时间、复苏的持续时间和ROSC)相匹配,得出了相似的结果(OR为0.8;95%CI为0.5-1.3;P=0.41)。在体外CPR组中,与医院生存相关的因素包括最初的电击性节律(OR为3.9;95%CI为1.5-10.3;P=0.005)、ECMO之前的短暂ROSC(OR为2.3;95%CI为1.1-4.7);P=0.03)和院前ECMO植入(OR为2.9;95%CI为1.5-5.9;P=0.002)。

由此可见,在基于人群的登记中,有4%的OHCA接受了体外CPR治疗,但与医院生存率提高无关。早期植入ECMO可能会改善患者结局。初始心律和ROSC可能有助于选择进行体外CPR的患者。 

原始出处:

Wulfran Bougouin.et al.Extracorporeal cardiopulmonary resuscitation in out-of-hospital cardiac arrest: a registry study.Eur Heart J.2019.https://doi.org/10.1093/eurheartj/ehz753

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    2020-05-31 aids222
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    2019-11-05 lizhou0204
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    2019-11-05 zhaojie88
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    2019-11-05 slcumt

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