微小肺癌——影像诊断与应对策略

2016-07-15 MedSci MedSci原创

本书将集中讨论微小肺癌这一当前肺癌筛查中的热点问题,系统阐述张国桢教授提出的微小肺癌诊治的“四抓”原则,即抓早(0期肺癌);抓小(≤10 mm AIS);抓准(术前正确诊断);抓好(临床、影像、病理互相协作配合好,保证病理取材的准确性)。在本书的第一部分,重视胸部解剖,详细描述肺部的横断面解剖结构及CT图像后处理的技术方法作为阅读本书的基础。并由不同学科的专家述评目前微小肺癌的筛查、病理学和影像学



内容提要:
    本书将集中讨论微小肺癌这一当前肺癌筛查中的热点问题,系统阐述张国桢教授提出的微小肺癌诊治的“四抓”原则,即抓早(0期肺癌);抓小(≤10 mm AIS);抓准(术前正确诊断);抓好(临床、影像、病理互相协作配合好,保证病理取材的准确性)。在本书的第一部分,重视胸部解剖,详细描述肺部的横断面解剖结构及CT图像后处理的技术方法作为阅读本书的基础。并由不同学科的专家述评目前微小肺癌的筛查、病理学和影像学(包括PET/CT)研究进展;第二部分将着重介绍不同形态微小肺癌的影像学特点、鉴别诊断要点和病理学基础。借鉴美国权威肿瘤研究机构NCCN的肺癌筛查指南,将微小肺癌分为纯磨玻璃、混合型或半实性磨玻璃和实性病灶分别加以讨论,以助于与国际早期肺癌的研究进展接轨。本部分还将详细讨论和阐述张国桢教授提出的CT血管造影“肿瘤微血管CT成像征”对于判断微小肺癌的使用价值。在第三部分,将对微小结节肺癌的应对策略加以讨论,包括外科手术和非手术治疗,如立体定向放疗和射频消融治疗等,使读者对于微小肺癌的诊疗有更全面的认识。为了突出本书临床实用性和加深读者对微小肺癌的认识,本书最后部分附录52例典型良恶性微小结节的临床病例,并附有精彩的分析及点评,具有示范性、实用性和指导性,也便于读者的自测和学习提高。


导读性前言:
    据全国肿瘤登记中心2014年统计数据表明,肺癌的发病率及病死率高居我国癌症榜首,并呈逐年上升趋势。我国肺癌发病率近10年来增加了60%,病死率在过去30年增加了465%。预计在未来30年,中国因肺癌致死的人数将高达1800万人,成为世界第一肺癌大国。此外,在一些国家肺癌患者5年的生存率已达20%以上,但在我国却低于10%,这与患者发现时大部分已是晚期、预后甚差有很大关系。如何以最小的代价来提高早期肺癌的检出率仍为肺癌研究的重点。所以有必要通过低剂量CT(low-doseCT,LDCT)筛查早期肺癌,从而改善这一现状。近年的研究结果表明,LDCT年度筛查可发现0一I期肺癌,手术切除后10年的生存率可达92%,所有未治疗的I期患者将在5年内死亡。低剂量CT检查对肺癌的筛查能发现更多的早期肺癌患者肺内有局灶性磨玻璃结节的特征,无疑可提高肺癌的手术切除率,减少细胞学和小标本活检不能对肺腺癌进行组织分类的情况。但同时,低剂量CT筛查可发现更多小结节,通常是数量较多、大小不一、新旧交替、种类复杂、多无特征。这就给诊断带来新的问题。因此,提高早期肺微小腺癌的诊断和鉴别诊断水平始终是影像学研究的重要课题。

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1992245, encodeId=d1e3199224554, content=<a href='/topic/show?id=7e5a492636a' target=_blank style='color:#2F92EE;'>#应对策略#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49263, encryptionId=7e5a492636a, topicName=应对策略)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Sun Apr 09 18:43:00 CST 2017, time=2017-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=134355, encodeId=d1ad13435593, content=学习下~, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/96A4B35900FD02B08C46DE33C3A06890/100, createdBy=f4011956702, createdName=扬州国信商标, createdTime=Sat Sep 24 15:58:00 CST 2016, time=2016-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1445581, encodeId=dd16144558119, content=<a href='/topic/show?id=643e5031124' target=_blank style='color:#2F92EE;'>#影像诊断#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50311, encryptionId=643e5031124, topicName=影像诊断)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erGh2JQt8g9L1dqpdLyJ7EDClYbBfjvngmKJ6Vn8jCDHuYvHH6ZLao7bSXVr4okhjNU9ojr0SZFxQ/132, createdBy=12ec5143276, createdName=12498fa0m12暂无昵称, createdTime=Sun Jul 17 07:43:00 CST 2016, time=2016-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93187, encodeId=dca59318e58, content=等电子版, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=d0921674448, createdName=gyczyxy, createdTime=Sat Jul 16 12:42:00 CST 2016, time=2016-07-16, status=1, ipAttribution=)]
    2016-09-24 扬州国信商标

    学习下~

    0

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  4. [GetPortalCommentsPageByObjectIdResponse(id=1992245, encodeId=d1e3199224554, content=<a href='/topic/show?id=7e5a492636a' target=_blank style='color:#2F92EE;'>#应对策略#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49263, encryptionId=7e5a492636a, topicName=应对策略)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Sun Apr 09 18:43:00 CST 2017, time=2017-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=134355, encodeId=d1ad13435593, content=学习下~, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/96A4B35900FD02B08C46DE33C3A06890/100, createdBy=f4011956702, createdName=扬州国信商标, createdTime=Sat Sep 24 15:58:00 CST 2016, time=2016-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1445581, encodeId=dd16144558119, content=<a href='/topic/show?id=643e5031124' target=_blank style='color:#2F92EE;'>#影像诊断#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50311, encryptionId=643e5031124, topicName=影像诊断)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erGh2JQt8g9L1dqpdLyJ7EDClYbBfjvngmKJ6Vn8jCDHuYvHH6ZLao7bSXVr4okhjNU9ojr0SZFxQ/132, createdBy=12ec5143276, createdName=12498fa0m12暂无昵称, createdTime=Sun Jul 17 07:43:00 CST 2016, time=2016-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93187, encodeId=dca59318e58, content=等电子版, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=d0921674448, createdName=gyczyxy, createdTime=Sat Jul 16 12:42:00 CST 2016, time=2016-07-16, status=1, ipAttribution=)]
    2016-07-16 gyczyxy

    等电子版

    0