Br J Cancer:结肠癌患者术前全身炎症反应(SIR)测定的预后价值

2021-03-25 xiaozeng MedSci原创

每年全球大约诊断出120万例新的结肠癌病例以及约有500,000例的死亡病例。

每年全球大约诊断出120万例新的结肠癌病例以及约有500,000例的死亡病例。在英国,TNM II期和III期结肠癌各自约占诊断时新病例的25%。而该疾病的长期结局差异较大,因此仅根据整体TNM分期预测患者的预后并不理想。

既往研究显示,术前全身炎症反应(SIR)的增强是一个新的、有据可查的预后指标。然而,迄今为止,这种方法在常规临床实践中尚未得到充分利用。

使用基于急性期蛋白评分(mGPS)或差异白细胞计数(中性白细胞与淋巴细胞比率,NLR)测量的术前全身炎症反应(SIR)显示出了结肠癌切除术治愈后的预后意义。该研究旨在调查上述两种测量方式的补充使用,以更好地进行结果的分层分析。

病例的筛选

研究人员使用单因素/多因素分析(UVA/MVA)分析mGPS和NLR测量对接受结肠癌根治性手术的患者的生存的影响。使用系统性炎症分级(SIG)分析这些评分在预测患者OS/CSS中的协同作用。

系统性炎症分级(SIG)分层的患者总生存率

该研究共包括了178例TNM-I-III期结肠癌患者。MVA分析结果显示mGPS和NLR对患者的OS均很重要。mGPS分层的三年生??存率分别为83–58%(TNM-I–III)、87–65%(TNM-II)和75–49%(TNM-III),而NLR则为84–62%(TNM-I–III)、88–69%(TNM-II)和77-49%(TNM-III)。当mGPS和NLR结合的SIG分级为0/1/2/3/4时,患者的3年OS分别为88%/84%/76%/65%/60%,而CSS为93%/90%/82%/ 73%/70%。SIG分级揭示TNM II/III期疾病的OS分别为93–68%/82–48%,CSS为97–80%/86–58%。


综上,该研究结果表明,对于进行根治性手术的结肠癌患者,术前采用mGPS和NLR结合的SIG评分能够更好的测定患者的SIR反应。


原始出处:

Golder, A.M., McMillan, D.C., Park, J.H. et al. The prognostic value of combined measures of the systemic inflammatory response in patients with colon cancer: an analysis of 1700 patients. Br J Cancer (24 March 2021).

 

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=961875, encodeId=867f9618e577, content=<a href='/topic/show?id=d12d1042620a' target=_blank style='color:#2F92EE;'>#Br J Cancer#</a>点击查看更多相关话题,或评论点击插入您喜欢的话题, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=104262, encryptionId=d12d1042620a, topicName=Br J Cancer)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20221103/2796e00c9b4549e3b313ed9e7accc68f/b52d6d98bbe04782b5a4e2dd1ee80be2.jpeg, createdBy=078e1614372, createdName=MedSciZeng, createdTime=Fri Apr 30 17:23:02 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1662334, encodeId=9dad166233493, content=<a href='/topic/show?id=6a426545472' target=_blank style='color:#2F92EE;'>#测定#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65454, encryptionId=6a426545472, topicName=测定)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8db925396819, createdName=丁鹏鹏, createdTime=Wed Jul 28 01:51:20 CST 2021, time=2021-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1971085, encodeId=fbfc19e1085ef, content=<a href='/topic/show?id=874929e01cd' target=_blank style='color:#2F92EE;'>#全身炎症反应#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29701, encryptionId=874929e01cd, topicName=全身炎症反应)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e093393, createdName=luwei00, createdTime=Sun Dec 05 06:51:20 CST 2021, time=2021-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1320908, encodeId=847a132090826, content=<a href='/topic/show?id=43de6e0076f' target=_blank style='color:#2F92EE;'>#炎症反应#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67007, encryptionId=43de6e0076f, topicName=炎症反应)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b73f484, createdName=lsj628, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385249, encodeId=9f5e138524959, content=<a href='/topic/show?id=dc121001e22d' target=_blank style='color:#2F92EE;'>#预后价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100172, encryptionId=dc121001e22d, topicName=预后价值)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1516580, encodeId=be721516580e2, content=<a href='/topic/show?id=3b0329699d3' target=_blank style='color:#2F92EE;'>#全身炎症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29699, encryptionId=3b0329699d3, topicName=全身炎症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f6210986148, createdName=12498dd9m14暂无昵称, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=)]
    2021-04-30 MedSciZeng

    #Br J Cancer#点击查看更多相关话题,或评论点击插入您喜欢的话题

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=961875, encodeId=867f9618e577, content=<a href='/topic/show?id=d12d1042620a' target=_blank style='color:#2F92EE;'>#Br J Cancer#</a>点击查看更多相关话题,或评论点击插入您喜欢的话题, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=104262, encryptionId=d12d1042620a, topicName=Br J Cancer)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20221103/2796e00c9b4549e3b313ed9e7accc68f/b52d6d98bbe04782b5a4e2dd1ee80be2.jpeg, createdBy=078e1614372, createdName=MedSciZeng, createdTime=Fri Apr 30 17:23:02 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1662334, encodeId=9dad166233493, content=<a href='/topic/show?id=6a426545472' target=_blank style='color:#2F92EE;'>#测定#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65454, encryptionId=6a426545472, topicName=测定)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8db925396819, createdName=丁鹏鹏, createdTime=Wed Jul 28 01:51:20 CST 2021, time=2021-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1971085, encodeId=fbfc19e1085ef, content=<a href='/topic/show?id=874929e01cd' target=_blank style='color:#2F92EE;'>#全身炎症反应#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29701, encryptionId=874929e01cd, topicName=全身炎症反应)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e093393, createdName=luwei00, createdTime=Sun Dec 05 06:51:20 CST 2021, time=2021-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1320908, encodeId=847a132090826, content=<a href='/topic/show?id=43de6e0076f' target=_blank style='color:#2F92EE;'>#炎症反应#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67007, encryptionId=43de6e0076f, topicName=炎症反应)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b73f484, createdName=lsj628, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385249, encodeId=9f5e138524959, content=<a href='/topic/show?id=dc121001e22d' target=_blank style='color:#2F92EE;'>#预后价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100172, encryptionId=dc121001e22d, topicName=预后价值)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1516580, encodeId=be721516580e2, content=<a href='/topic/show?id=3b0329699d3' target=_blank style='color:#2F92EE;'>#全身炎症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29699, encryptionId=3b0329699d3, topicName=全身炎症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f6210986148, createdName=12498dd9m14暂无昵称, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=)]
    2021-07-28 丁鹏鹏
  3. [GetPortalCommentsPageByObjectIdResponse(id=961875, encodeId=867f9618e577, content=<a href='/topic/show?id=d12d1042620a' target=_blank style='color:#2F92EE;'>#Br J Cancer#</a>点击查看更多相关话题,或评论点击插入您喜欢的话题, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=104262, encryptionId=d12d1042620a, topicName=Br J Cancer)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20221103/2796e00c9b4549e3b313ed9e7accc68f/b52d6d98bbe04782b5a4e2dd1ee80be2.jpeg, createdBy=078e1614372, createdName=MedSciZeng, createdTime=Fri Apr 30 17:23:02 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1662334, encodeId=9dad166233493, content=<a href='/topic/show?id=6a426545472' target=_blank style='color:#2F92EE;'>#测定#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65454, encryptionId=6a426545472, topicName=测定)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8db925396819, createdName=丁鹏鹏, createdTime=Wed Jul 28 01:51:20 CST 2021, time=2021-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1971085, encodeId=fbfc19e1085ef, content=<a href='/topic/show?id=874929e01cd' target=_blank style='color:#2F92EE;'>#全身炎症反应#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29701, encryptionId=874929e01cd, topicName=全身炎症反应)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e093393, createdName=luwei00, createdTime=Sun Dec 05 06:51:20 CST 2021, time=2021-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1320908, encodeId=847a132090826, content=<a href='/topic/show?id=43de6e0076f' target=_blank style='color:#2F92EE;'>#炎症反应#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67007, encryptionId=43de6e0076f, topicName=炎症反应)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b73f484, createdName=lsj628, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385249, encodeId=9f5e138524959, content=<a href='/topic/show?id=dc121001e22d' target=_blank style='color:#2F92EE;'>#预后价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100172, encryptionId=dc121001e22d, topicName=预后价值)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1516580, encodeId=be721516580e2, content=<a href='/topic/show?id=3b0329699d3' target=_blank style='color:#2F92EE;'>#全身炎症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29699, encryptionId=3b0329699d3, topicName=全身炎症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f6210986148, createdName=12498dd9m14暂无昵称, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=961875, encodeId=867f9618e577, content=<a href='/topic/show?id=d12d1042620a' target=_blank style='color:#2F92EE;'>#Br J Cancer#</a>点击查看更多相关话题,或评论点击插入您喜欢的话题, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=104262, encryptionId=d12d1042620a, topicName=Br J Cancer)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20221103/2796e00c9b4549e3b313ed9e7accc68f/b52d6d98bbe04782b5a4e2dd1ee80be2.jpeg, createdBy=078e1614372, createdName=MedSciZeng, createdTime=Fri Apr 30 17:23:02 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1662334, encodeId=9dad166233493, content=<a href='/topic/show?id=6a426545472' target=_blank style='color:#2F92EE;'>#测定#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65454, encryptionId=6a426545472, topicName=测定)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8db925396819, createdName=丁鹏鹏, createdTime=Wed Jul 28 01:51:20 CST 2021, time=2021-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1971085, encodeId=fbfc19e1085ef, content=<a href='/topic/show?id=874929e01cd' target=_blank style='color:#2F92EE;'>#全身炎症反应#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29701, encryptionId=874929e01cd, topicName=全身炎症反应)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e093393, createdName=luwei00, createdTime=Sun Dec 05 06:51:20 CST 2021, time=2021-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1320908, encodeId=847a132090826, content=<a href='/topic/show?id=43de6e0076f' target=_blank style='color:#2F92EE;'>#炎症反应#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67007, encryptionId=43de6e0076f, topicName=炎症反应)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b73f484, createdName=lsj628, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385249, encodeId=9f5e138524959, content=<a href='/topic/show?id=dc121001e22d' target=_blank style='color:#2F92EE;'>#预后价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100172, encryptionId=dc121001e22d, topicName=预后价值)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1516580, encodeId=be721516580e2, content=<a href='/topic/show?id=3b0329699d3' target=_blank style='color:#2F92EE;'>#全身炎症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29699, encryptionId=3b0329699d3, topicName=全身炎症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f6210986148, createdName=12498dd9m14暂无昵称, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=961875, encodeId=867f9618e577, content=<a href='/topic/show?id=d12d1042620a' target=_blank style='color:#2F92EE;'>#Br J Cancer#</a>点击查看更多相关话题,或评论点击插入您喜欢的话题, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=104262, encryptionId=d12d1042620a, topicName=Br J Cancer)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20221103/2796e00c9b4549e3b313ed9e7accc68f/b52d6d98bbe04782b5a4e2dd1ee80be2.jpeg, createdBy=078e1614372, createdName=MedSciZeng, createdTime=Fri Apr 30 17:23:02 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1662334, encodeId=9dad166233493, content=<a href='/topic/show?id=6a426545472' target=_blank style='color:#2F92EE;'>#测定#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65454, encryptionId=6a426545472, topicName=测定)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8db925396819, createdName=丁鹏鹏, createdTime=Wed Jul 28 01:51:20 CST 2021, time=2021-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1971085, encodeId=fbfc19e1085ef, content=<a href='/topic/show?id=874929e01cd' target=_blank style='color:#2F92EE;'>#全身炎症反应#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29701, encryptionId=874929e01cd, topicName=全身炎症反应)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e093393, createdName=luwei00, createdTime=Sun Dec 05 06:51:20 CST 2021, time=2021-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1320908, encodeId=847a132090826, content=<a href='/topic/show?id=43de6e0076f' target=_blank style='color:#2F92EE;'>#炎症反应#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67007, encryptionId=43de6e0076f, topicName=炎症反应)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b73f484, createdName=lsj628, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385249, encodeId=9f5e138524959, content=<a href='/topic/show?id=dc121001e22d' target=_blank style='color:#2F92EE;'>#预后价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100172, encryptionId=dc121001e22d, topicName=预后价值)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1516580, encodeId=be721516580e2, content=<a href='/topic/show?id=3b0329699d3' target=_blank style='color:#2F92EE;'>#全身炎症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29699, encryptionId=3b0329699d3, topicName=全身炎症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f6210986148, createdName=12498dd9m14暂无昵称, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=961875, encodeId=867f9618e577, content=<a href='/topic/show?id=d12d1042620a' target=_blank style='color:#2F92EE;'>#Br J Cancer#</a>点击查看更多相关话题,或评论点击插入您喜欢的话题, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=104262, encryptionId=d12d1042620a, topicName=Br J Cancer)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20221103/2796e00c9b4549e3b313ed9e7accc68f/b52d6d98bbe04782b5a4e2dd1ee80be2.jpeg, createdBy=078e1614372, createdName=MedSciZeng, createdTime=Fri Apr 30 17:23:02 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1662334, encodeId=9dad166233493, content=<a href='/topic/show?id=6a426545472' target=_blank style='color:#2F92EE;'>#测定#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65454, encryptionId=6a426545472, topicName=测定)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8db925396819, createdName=丁鹏鹏, createdTime=Wed Jul 28 01:51:20 CST 2021, time=2021-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1971085, encodeId=fbfc19e1085ef, content=<a href='/topic/show?id=874929e01cd' target=_blank style='color:#2F92EE;'>#全身炎症反应#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29701, encryptionId=874929e01cd, topicName=全身炎症反应)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e093393, createdName=luwei00, createdTime=Sun Dec 05 06:51:20 CST 2021, time=2021-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1320908, encodeId=847a132090826, content=<a href='/topic/show?id=43de6e0076f' target=_blank style='color:#2F92EE;'>#炎症反应#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67007, encryptionId=43de6e0076f, topicName=炎症反应)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b73f484, createdName=lsj628, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385249, encodeId=9f5e138524959, content=<a href='/topic/show?id=dc121001e22d' target=_blank style='color:#2F92EE;'>#预后价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100172, encryptionId=dc121001e22d, topicName=预后价值)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1516580, encodeId=be721516580e2, content=<a href='/topic/show?id=3b0329699d3' target=_blank style='color:#2F92EE;'>#全身炎症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29699, encryptionId=3b0329699d3, topicName=全身炎症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f6210986148, createdName=12498dd9m14暂无昵称, createdTime=Sat Mar 27 14:51:20 CST 2021, time=2021-03-27, status=1, ipAttribution=)]

相关资讯

JCC:炎症性肠病患者会导致结肠癌诊断时间提前但是预后较差

炎症性肠病[IBD]是结肠癌的已知危险因素,占大肠癌[CRC]的1-2%左右。纵向研究表明,结肠炎症的程度,肠蠕动时间以及原发性硬化性胆管炎是CRC发生的前期疾病。

Gastroenterology:重复粪便免疫化学测试与乙状结肠镜检查对结直肠癌筛查的准确性差异

结直肠癌(CRC)是一种相对高发的肿瘤疾病,成为了全球健康成本的主要负担,2018年全球估计有180万新发病例,因此,尽早进行结肠癌筛查可以有效降低肿瘤的发生。

Gastroenterology:一种新型益生菌——嗜热链球菌可以抑制结直肠肿瘤发生

大肠癌(CRC)是全球第三大常见癌症,也是第四大癌症相关死亡的主要原因。

DCR:直肠癌患者行结肠切除后切缘阳性及术后并发症的高发的风险分析

大多数直肠癌都局限在直肠系膜筋膜内,尤其是在引入直肠癌早期筛查之后,全直肠系膜切除术(TME)是具有优异长期效果的标准外科手术切除术。

AJG:人体中性激素的异常与胃癌和结肠直肠癌有关,而与食管腺癌无关

无论是食道癌,胃癌还是结肠直肠癌都有一个无法解释的现象那就是男性占大多数。特别是是食管癌中,男性的发病率比女性高8倍。

Gastroenterology :45岁后要定期做肠镜

45-49岁时接受结肠镜检查与随后的大肠癌发病率显著降低有很强的相关性。