Int J Pediatr Otorhinolaryngol:先天性巨细胞病毒感染儿童的人工耳蜗植入结果

2020-11-16 AlexYang MedSci原创

到目前为止,巨细胞病毒(cCMV)是儿童永久性感音神经性听力损失(SNHL)最常见的非遗传性先天性病因,也是造成发育和神经系统残疾的主要感染性原因。最近,有研究人员阐释了由有症状或无症状的cCMV感染

到目前为止,巨细胞病毒(cCMV)是儿童永久性感音神经性听力损失(SNHL)最常见的非遗传性先天性病因,也是造成发育和神经系统残疾的主要感染性原因。最近,有研究人员阐释了由有症状或无症状的cCMV感染而导致重度至深度感音神经性听力损失的儿童的人工耳蜗植入结果,特别是比较了其与匹配的突变Connexin 26(Cx26)植入患者的表现结果。

研究是一个回顾性病例对照研究。研究人员收集了有症状cCMV和无症状cCMV患者的临床资料,并与年龄和CI前(人工耳蜗植入前)语言类别相匹配的Cx26患者的临床资料进行了比较;所有受试者均受双侧重度至深度SNHL影响,并接受CI和语言康复治疗。结果表明,统计学分析显示三个小组CI前感知类别和语言水平无显著差异,有症状cCMV组语言阶段表现随时间推移显著更差(P=0.017)。另外,他们的数据支持了受cCMV影响的儿童的语言能力能够随着时间的推移而改善,尽管与无症状的cCMV和Cx26突变组相比,有症状的cCMV组在CI后3-4年取得的语言阶段较低。

随着时间的功能性语言发展评估

最后,研究人员指出,到目前为止,CI辅以言语治疗可以认为是对cCMV相关的重度至深度听力损失儿童的有效干预措施。

原始出处:

Virginia Corazzi, Andrea Ciorba, Chiara Bianchini et al. Outcome of cochlear implantation in children with congenital Cytomegalovirus infection: A retrospective case control study. Int J Pediatr Otorhinolaryngol. Nov 2020

 

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beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201022/72c91d73e2ce4d7b9c5c2632e334c6f9/2ca937aa7ec64d0a834d958d18104b30.jpg, createdBy=77a62581282, createdName=Ash.L, createdTime=Mon Nov 16 17:37:26 CST 2020, time=2020-11-16, status=1, ipAttribution=)]
    2020-11-18 weiyuan.fang85

    学习

    0

  5. 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encryptionId=bc9f28589d0, topicName=先天性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a435298, createdName=huirong, createdTime=Wed Nov 18 05:26:14 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502289, encodeId=ce5c1502289c1, content=<a href='/topic/show?id=021d4821096' target=_blank style='color:#2F92EE;'>#巨细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48210, encryptionId=021d4821096, topicName=巨细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11759518880, createdName=wwzzly, createdTime=Wed Nov 18 05:26:14 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520713, encodeId=bdb11520e13b6, content=<a href='/topic/show?id=7a736264553' target=_blank style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201022/72c91d73e2ce4d7b9c5c2632e334c6f9/2ca937aa7ec64d0a834d958d18104b30.jpg, createdBy=77a62581282, createdName=Ash.L, createdTime=Mon Nov 16 17:37:26 CST 2020, time=2020-11-16, status=1, ipAttribution=)]
  6. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201022/72c91d73e2ce4d7b9c5c2632e334c6f9/2ca937aa7ec64d0a834d958d18104b30.jpg, createdBy=77a62581282, createdName=Ash.L, createdTime=Mon Nov 16 17:37:26 CST 2020, time=2020-11-16, status=1, ipAttribution=)]
    2020-11-18 huirong
  7. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201022/72c91d73e2ce4d7b9c5c2632e334c6f9/2ca937aa7ec64d0a834d958d18104b30.jpg, createdBy=77a62581282, createdName=Ash.L, createdTime=Mon Nov 16 17:37:26 CST 2020, time=2020-11-16, status=1, ipAttribution=)]
    2020-11-18 wwzzly
  8. 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    2020-11-18 jiyangfei
  9. 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    2020-11-16 Ash.L

    学习了

    0

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