Arch Phys Med Rehabil:力量或氧训练可有效改善老年痴呆症患者的日常活动能力

2020-12-06 MedSci原创 MedSci原创

本项单盲随机对照试验旨在确定力量或有氧训练是否可以老年痴呆症患者的日常生活活动提供更多的益处,并确定运动对认知、抑郁和生化标志物的影响,研究结果已在线发表于Arch Phys Med Rehabil。

本项单盲随机对照试验旨在确定力量或有氧训练是否可以老年痴呆症患者的日常生活活动提供更多的益处,并确定运动对认知、抑郁和生化标志物的影响,研究结果已在线发表于Arch Phys Med Rehabil。

研究在一个退伍军人的养老院进行,纳入80名志愿者,迷你精神状态检查的分数在15到26分之间。由于心肺或骨科疾病禁止运动训练,以及存在可能阻碍回答问卷内容的认知问题,11名参与者被排除在外。在运动训练期间,有8名参与者自愿退出研究。

 

将剩余的参与者随机分配进行力量或有氧训练,共4周。主要结果测量是Barthel指数。其他结果测量包括迷你精神状态检查、蒙特利尔认知评估、老年抑郁量表、血浆单核细胞趋化蛋白-1水平、胰岛素样生长因子-1水平和血清脑源性神经营养因子水平。

结果显示,在完成该项目后,力量训练组患者的巴特尔指数,迷你精神状态检查,蒙特利尔认知评估,和血浆单核细胞化学活性蛋白-1水平得到显著改善。对于接受过有氧训练的患者,其血清脑源性神经营养因子也有明显改善。然而,关于这些结果措施的改善程度两组之间无明显的统计学差异。

 

综上所述,该研究结果表明,无论是力量训练还是有氧训练,为期4周的强化运动计划都能为老年痴呆症患者带来显著的益处,而通过有氧训练,血清中的脑源性神经营养因子也得到了额外的改善。

 

原始出处:

 

I-Ting Liu, Wei-Ju Lee, et al., Therapeutic Effects of Exercise Training on Elderly Patients With Dementia: A Randomized Controlled Trial. Arch Phys Med Rehabil. 2020 May;101(5):762-769. doi: 10.1016/j.apmr.2020.01.012.  

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    2021-08-14 Boyinsh
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    2020-12-07 qjddjq
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    2020-12-06 Belle姑娘

    最近出了好多有关运动干预的研究,学习

    0

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    2020-12-06 junJUN

    老年人痴呆何药可用??

    0

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