Diabetologia:妊娠期高血压患者后续罹患糖尿病的风险大大增加!

2021-01-12 Nebula MedSci原创

妊娠期高血压(HDP)病史和随后发生2型糖尿病(统称为糖尿病)之间的关联仍然没有定论。本报告回顾了最新的证据来量化既往HDP病史与罹患糖尿病的相关性。

妊娠期高血压(HDP)病史和随后发生2型糖尿病(统称为糖尿病)之间的关联仍然没有定论。本报告回顾了最新的证据来量化既往HDP病史与罹患糖尿病的相关性。

从MEDLINE、EMBASE和CINAHL数据库中检索2020年2月17日前关于HDP(先兆子痫或妊娠期高血压)与糖尿病发病关系的观察性研究。排除孕前就患有糖尿病女性的研究。

通过对4617篇文章进行检索后,最终本分析纳入了16项队列研究(包括5项未分类的HDP、4项先兆子痫、7项妊高症和先兆子痫),共涵盖3,095,457名受试者。

妊娠期高血压与后续罹患糖尿病的风险

有任何HDP病史的女性后续罹患糖尿病的风险均显著增加(调整危险比[aHR]:HDP 2.24、妊娠期高血压 2.19、先兆子痫 2.56、早产先兆子痫 3.05)。经妊娠期糖尿病相关研究校正后,HDP和糖尿病之间的相关性仍持续存在(aHR 2.01)。

综上所述,HDP与较高的糖尿病风险独立相关。需要进一步研究以确定HDP如何有助于糖尿病风险预测,以制定循证筛查预防策略。

原始出处:

Zhao, G., Bhatia, D., Jung, F. et al. Risk of type 2 diabetes mellitus in women with prior hypertensive disorders of pregnancy: a systematic review and meta-analysis. Diabetologia (2021). https://doi.org/10.1007/s00125-020-05343-w

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    2021-01-13 12346c4dm64暂无昵称

    妊娠期,人群

    0

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    2021-01-13 misszhang

    谢谢MedSci提供最新的资讯

    0

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    2021-01-12 wxl882001

    了解

    0

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    2021-01-12 薄荷糖OOO

    #学习#学习了

    0

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