JCEM:妊娠糖尿病子女学业成绩受影响吗?

2021-06-23 MedSci原创 MedSci原创

O-GDM个体的学业表现略低于O-BP个体。然而,这种差异不太可能具有临床意义。

妊娠糖尿病 (GDM) 的患病率正在增加,宫内高血糖被怀疑会影响子代的认知功能。 近日,内分泌和代谢性疾病领域权威杂志Journal of Clinical Endocrinology & Metabolism上发表了一篇研究文章,研究人员旨在通过对接受义务教育的15-16岁儿童的平均绩点 (GPA)来评估其学业成绩,并将暴露于GDM(O-GDM) 与来自一般人群(O-BP)的子代学业成绩进行比较。 该队列研究的参与者为1994年至2001年期间在丹麦出生的所有单胎人员(O-GDM:n=4286;O-BP:n=501045)。在单变量和多变量线性模型中比较标准化和国际可比性的GPA。该研究的主要结局指标为GPA的调整后平均差异。研究人员还分析了高GPA、GPA低于及格线和未登记GPA的概率。 O-GDM的GPA为6.29(SD为2.52),而O-BP的GPA为6.78(SD为2.50)。调整后的平均差为-0.36[95%置信区间 (CI)为-0.44;-0.29],对应的Cohens D值为0.14。O-GDM参与者获得高GPA的可能性较低(调整后的比值比(aOR)为0.68[

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    2021-12-12 smallant2015
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    2021-12-29 achengzhao
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    2021-06-24 misszhang

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