Clinical Nutrition: 胃切除术后早期口服肠内营养的耐受性及预测肠衰竭的危险因素

2020-11-15 MedSci原创 MedSci原创

许多研究表明,胃切除术后早期口服肠内营养是可行与安全的。但是,很少研究早期口服肠内营养的耐受性。 这项研究旨在调查早期口服营养的耐受性以及影响胃切除术后肠衰竭的因素。

背景与目标

许多研究表明,胃切除术后早期口服肠内营养是可行与安全的。但是,很少研究早期口服肠内营养的耐受性。 这项研究旨在调查早期口服营养的耐受性以及影响胃切除术后肠衰竭的因素。

方法

研究人员回顾性分析了565例胃癌切除术后并在术后第1天接受口服肠内营养的胃癌患者。早期口服肠内营养耐受不良的定义为由于任何原因而停止进食。最后研究分析了与早期口服肠内营养不良相关的术前临床信息和手术因素。

 

结果

胃切除术后早期口服肠内营养的耐受性为74.7%。在565例患者中,有72例(12.7%)由于不良的胃肠道症状而导致早期口服营养失败,52例(9.2%)由于胃淤滞或肠梗阻而失败,而19例(3.4%)由于其他术后并发症而失败。在单变量分析中,年龄(≥70岁),男性,术前肿瘤阻塞,残余胃癌,开放手术,手术时间(≥4h)与早期口服肠内营养不良有关。这些因素的多变量分析显示,男性,术前肠梗阻,手术时间是胃切除术后早期口服肠内营养不耐受的独立预测因素。

结论

胃切除术后早期口服肠内营养的耐受性可与其他胃肠道手术相似,可以尽早使用,只是需要鉴别是否存在危险因素即可。

原始出处:

Aelee Jang. Et al. Tolerability of early oral nutrition and factors predicting early oral nutrition failure after gastrectomy. Clinical Nutrition.2020.

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    2020-11-17 zll0628
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    2020-11-17 bshuang

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