JCO:子宫癌诊断后待手术时间影响生存期

2013-12-06 小康 医学论坛网

加拿大学者的一项研究表明,子宫癌患者诊断后待手术时间越长,总生存期越短。研究论文11月25日在线发表于《临床肿瘤学杂志》(J Clin Oncol)。研究目的:确定子宫癌病理诊断后患者等待子宫切除术的时间对全因死亡率是否有影响。研究者利用安大略癌症登记处数据库2000年4月1日至2009年3月31日的资料,确定了组织病理学诊断为子宫癌并接受手术治疗的患者,并进行了统计分析。结果显示:• 最终受试人

加拿大学者的一项研究表明,子宫癌患者诊断后待手术时间越长,总生存期越短。研究论文11月25日在线发表于《临床肿瘤学杂志》(J Clin Oncol)。【原文下载】

研究目的:确定子宫癌病理诊断后患者等待子宫切除术的时间对全因死亡率是否有影响。

研究者利用安大略癌症登记处数据库2000年4月1日至2009年3月31日的资料,确定了组织病理学诊断为子宫癌并接受手术治疗的患者,并进行了统计分析。

结果显示:

• 最终受试人群包括9417名女性,其中51.9%由妇科医生进行手术,69.9%为子宫内膜样腺癌。

 • 待手术时间为0.1~2、2.1~6、6.1~12和>12周患者的5年生存率分别为71.1%、81.8%、79.5%和71.9%。

• 多变量分析显示,在校正了其他显著因素后,待手术时间≤2周预示生存期不佳。待手术时间>12周患者的生存期短于2.1~12周的患者。

原文出处:

Elit LM, O'Leary EM, Pond GR, Seow HY.Impact of Wait Times on Survival for Women With Uterine Cancer.J Clin Oncol. 2013 Nov 25.【原文下载】

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    2014-08-01 lidong40
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