JACC:CVD一级预防:可通过管理糖尿病、高脂血症和高血压而实现?

2017-12-26 闫盈盈 环球医学

因为高血压、糖尿病、高脂血症等问题,血管会经历“沉积-钙化-狭窄-破裂/闭塞”这样一个病变过程后,最终走向的结局就是我们所熟悉的心脑血管急性事件。2017年发表在《J Am Coll Cardiol》上的一项摘要,对冠心病的一级预防可通过管理糖尿病、高脂血症和高血压而实现进行了描述。

因为高血压糖尿病、高脂血症等问题,血管会经历“沉积-钙化-狭窄-破裂/闭塞”这样一个病变过程后,最终走向的结局就是我们所熟悉的心脑血管急性事件。2017年发表在《J Am Coll Cardiol》上的一项摘要,对冠心病的一级预防可通过管理糖尿病、高脂血症和高血压而实现进行了描述。

糖尿病、高脂血症、高血压为预测心血管疾病事件中可管理的风险因素。这些风险因素对心血管疾病的影响随着血糖、低密度脂蛋白胆固醇和血压水平的逐步升高而增加。这些可管理风险因素的初始治疗阈值和风险因素影响的最佳目标为一级预防研究的关注焦点。虽然积极治疗的方法是必要的,但是不良事件会发生,存在潜在生理障碍。本文通过总结现有指南和纳入了一级预防队列的干预性试验的相关临床试验数据,讨论了冠心病的一级预防,该一级预防可通过管理糖尿病、高脂血症和高血压而实现。

原始出处:
Hong KN, Fuster V, Rosenson RS,et al. How Low to Go With Glucose, Cholesterol,?and Blood Pressure in Primary?Prevention of CVD.J Am Coll Cardiol. 2017 Oct 24;70(17):2171-2185. doi: 10.1016/j.jacc.2017.09.001.

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    2018-07-11 hbwxf
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    2017-12-28 pcw111