Nat Med:农场灰尘微生物或可缓解城市儿童哮喘

2019-06-23 Nature自然科研 Nature自然科研

《自然-医学》本周在线发表的一项研究Farm-like indoor microbiota in non-farm homes protects children from asthma development发现,暴露在农场样房屋灰尘微生物组中可能与城市儿童的哮喘发生率降低相关。

《自然-医学》本周在线发表的一项研究Farm-like indoor microbiota in non-farm homes protects children from asthma development发现,暴露在农场样房屋灰尘微生物组中可能与城市儿童的哮喘发生率降低相关。



农场和非农场住宅的室内微生物群差异  来源:Kirjavainen et al.

哮喘的发生被证实与城镇化相关,这可能是因为城镇化过程中失去了关键的屋尘微生物种类,而这些微生物仍存在于农场。不过此前并不清楚农场细菌出现在城市环境中是否也与哮喘患病率下降相关。

芬兰国家健康与福利研究所的Pirkka Kirjavainen和同事对395名芬兰农村和郊区儿童家中的屋尘微生物群进行了研究,发现了一种与农场住宅相关的独特的微生物丰度模式。作者随后又在1031名德国儿童组成的队列中重复了这一结果,发现如果非农场住宅的室内微生物群与芬兰农场住宅的类似,住在这里的儿童的哮喘风险也更低。

个别微生物种类是否能直接预防哮喘,这项观察性研究并未给出定论,但却进一步肯定了环境源细菌在哮喘发展中的作用。作者认为,测定居住区的微生物群构成或有利于评估和监测郊区以及城市儿童患哮喘的相关风险。

原始出处:
Pirkka V. Kirjavainen, Anne M. Karvonen, Rachel I. Adams, et al. Farm-like indoor microbiota in non-farm homes protects children from asthma development. Nature Medicine. Jun 2019.

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    2019-09-22 wjcjjian
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    2019-11-05 liye789132251
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1825053, encodeId=9460182505324, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Sun Sep 22 15:16:00 CST 2019, time=2019-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1883736, encodeId=f2aa1883e368d, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Tue Nov 05 03:16:00 CST 2019, time=2019-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295964, encodeId=66cb129596407, content=<a href='/topic/show?id=5d41282361d' target=_blank style='color:#2F92EE;'>#儿童哮喘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28236, encryptionId=5d41282361d, topicName=儿童哮喘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a885259, createdName=yourmama, createdTime=Tue Jun 25 09:16:00 CST 2019, time=2019-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609836, encodeId=0fc0160983639, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue Jun 25 09:16:00 CST 2019, time=2019-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=368258, encodeId=9124368258bc, content=666, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/01/04/2540fb84decb81d47a7f2868070e6cbd.jpg, createdBy=ed3f2205793, createdName=百草, createdTime=Mon Jun 24 06:19:06 CST 2019, time=2019-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=368228, encodeId=7c8b36822855, content=学习了很有用不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Mon Jun 24 00:07:48 CST 2019, time=2019-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=368221, encodeId=88e736822104, content=出生6个月内屋尘可以训练婴儿的免疫功能,因此出生后赃一点,反而不易得过敏和哮喘, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Sun Jun 23 20:01:12 CST 2019, time=2019-06-23, status=1, ipAttribution=)]
    2019-06-24 百草

    666

    0

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    2019-06-24 飛歌

    学习了很有用不错

    0

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    2019-06-23 lovetcm

    出生6个月内屋尘可以训练婴儿的免疫功能,因此出生后赃一点,反而不易得过敏和哮喘

    0