脑膜炎球菌疫苗MenQuadfi获得欧盟批准

2020-11-29 Allan MedSci原创

脑膜炎球菌病可以在短短的一天之内夺走生命,并使幸存者患有严重的永久性残疾。

脑膜炎奈瑟氏菌是引起细菌性脑膜炎和脓毒症的主要原因。最常发生在非洲撒哈拉以南地区的“脑膜炎地带”。侵入性脑膜炎球菌病有很高的致死率(>50%,如果未经处理)并且许多幸存者出现了永久性的后遗症。在 12 种识别出的脑膜炎奈瑟氏菌中,A、B、C、X、W 和 Y 是引起疾病的主要原因。

近日,法国制药公司赛诺菲(Sanofi)的脑膜炎球菌(MenACWY)疫苗MenQuadfi已获得欧盟(EC)的批准。MenQuadfi可以主动免疫12个月以上的个体,以抵抗由脑膜炎奈瑟氏球菌A、C、W和Y血清型引起的侵袭性脑膜炎球菌病。

该批准是基于赛诺菲MenQuadfi国际临床计划的结果,该计划包括七个II期和III期研究。赛诺菲的疫苗与所有其他上市的疫苗进行了比较,证明了MenQuadfi具有良好的安全性,并在整个研究中始终对所有四个血清型产生了高免疫应答。

赛诺菲巴斯德负责人Thomas Triomphe说:“脑膜炎球菌病可以在短短的一天之内夺走生命,并使幸存者患有严重的永久性残疾。在欧洲,2018年有3,000例侵袭性脑膜炎球菌病病例,其中一半是由C、W和Y血清型引起的”。

 

原始出处:

http://www.pharmatimes.com/news/sanofis_meningococcal_vaccine_gets_eu_approval_1357543

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    2020-11-30 ms8000001080131379

    希望造福人类

    0

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    2020-11-29 ms9000001235733856

    脑膜炎奈瑟氏菌是引起细菌性脑膜炎和脓毒症的主要原因?。

    0

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