Lasers Med Sci:非剥脱性点阵激光疗法治疗酒糟鼻患者面部痤疮疤痕的疗效

2021-09-15 MedSci原创 MedSci原创

痤疮疤痕是痤疮的一种常见并发症,对患者的身体和社会心理产生了负面影响。酒糟鼻是一种面部中央皮肤的慢性炎症性疾病,大约有三分之一的患者同时出现痤疮和酒糟鼻。非剥脱性点阵激光器常用于治疗面部毛孔、光老化和

痤疮疤痕是痤疮的一种常见并发症,对患者的身体和社会心理产生了负面影响。酒糟鼻是一种面部中央皮肤的慢性炎症性疾病,大约有三分之一的患者同时出现痤疮和酒糟鼻。非剥脱性点阵激光器常用于治疗面部毛孔、光老化和痤疮疤痕,或是酒糟鼻患者痤疮疤痕的更好治疗选择。然而,目前还没有关于面部皮肤疾病治疗的前瞻性研究报告,发表于Lasers Med Sci的一项研究评估了非剥脱性点阵激光(1440-nm NAFL)治疗酒糟鼻患者萎缩性痤疮疤痕的疗效和安全性。

在这项前瞻性的干预性研究中,研究人员纳入了32名酒糟鼻和痤疮疤痕患者,接受了三次1440-nm NAFL治疗。对疗效、表皮屏障功能和副作用进行了评估。

结果,30名患者完成了治疗,三次治疗后,痤疮疤痕的中位数从45(30,50)明显减少到15(15,30)(P < 0.001)。痤疮疤痕的改善得分是2.7±0.7;22人(73.3%)表示满意或非常满意。酒糟鼻红斑评分从2.1±0.4变为1.9±0.5(P=0.326),潮红、灼热和刺痛没有加重。治疗后的油脂含量明显减少(P < 0.001),而皮肤屏障功能的其他指标没有明显差异。生活质量评分从17.5 ± 3.8降至14.1 ± 3.0(P < 0.001)。没有观察到严重的副作用。

综上,该研究结果表明,1440纳米NAFL疗法在治疗酒糟鼻患者的痤疮疤痕方面是有效的,对皮肤屏障的损害很小。

原始出处:

Ben Wang, et al., Efficacy of non-ablative fractional 1440-nm laser therapy for treatment of facial acne scars in patients with rosacea: a prospective, interventional study. Lasers Med Sci. 2021 Apr;36(3):649-655. doi: 10.1007/s10103-020-03107-x.

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    2022-03-02 anminleiryan
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    2021-12-04 俅侠
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    2021-09-17 oliver169
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    2021-09-17 HinsMax
  5. [GetPortalCommentsPageByObjectIdResponse(id=1878414, encodeId=2aac18e8414b9, content=<a href='/topic/show?id=c157696175' target=_blank style='color:#2F92EE;'>#ERS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6961, encryptionId=c157696175, topicName=ERS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e93e105, createdName=anminleiryan, createdTime=Wed Mar 02 13:01:19 CST 2022, time=2022-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1747907, encodeId=50a71e4790762, content=<a href='/topic/show?id=77d62883411' target=_blank style='color:#2F92EE;'>#光疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28834, encryptionId=77d62883411, topicName=光疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb1d35982112, createdName=俅侠, createdTime=Sat Dec 04 18:01:19 CST 2021, time=2021-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279790, encodeId=5d4412e97906f, content=<a href='/topic/show?id=265c66e50ea' target=_blank style='color:#2F92EE;'>#激光#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66750, encryptionId=265c66e50ea, topicName=激光)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4fd6156, createdName=oliver169, createdTime=Fri Sep 17 05:01:19 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1394127, encodeId=93c6139412e73, content=<a href='/topic/show?id=7b29e0460b1' target=_blank style='color:#2F92EE;'>#疤痕#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70460, encryptionId=7b29e0460b1, topicName=疤痕)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/qXbLjJB4FSzhQS3C5qQFMJkqicRIJFL6zHFwwhv0I95nzA6xicevQcEica0gk4A58UkbMMriadAgTY2b7N7Yd0ZsQg/132, createdBy=910c2500152, createdName=HinsMax, createdTime=Fri Sep 17 05:01:19 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1591685, encodeId=f1fb159168591, content=<a href='/topic/show?id=409d28835d6' target=_blank style='color:#2F92EE;'>#光疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28835, encryptionId=409d28835d6, topicName=光疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=477c17977507, createdName=fusion, createdTime=Fri Sep 17 05:01:19 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1611255, encodeId=6760161125539, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri Sep 17 05:01:19 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051503, encodeId=0a9610515038a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=821f2227826, createdName=DR.Fu SIR, createdTime=Wed Sep 15 15:41:15 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051512, encodeId=bb42105151249, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=2d785605234, createdName=ms4000000114765638, createdTime=Wed Sep 15 16:02:00 CST 2021, time=2021-09-15, status=1, ipAttribution=)]
    2021-09-17 fusion
  6. [GetPortalCommentsPageByObjectIdResponse(id=1878414, encodeId=2aac18e8414b9, content=<a href='/topic/show?id=c157696175' target=_blank style='color:#2F92EE;'>#ERS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6961, encryptionId=c157696175, topicName=ERS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e93e105, createdName=anminleiryan, createdTime=Wed Mar 02 13:01:19 CST 2022, time=2022-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1747907, encodeId=50a71e4790762, content=<a href='/topic/show?id=77d62883411' target=_blank style='color:#2F92EE;'>#光疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28834, encryptionId=77d62883411, topicName=光疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb1d35982112, createdName=俅侠, createdTime=Sat Dec 04 18:01:19 CST 2021, time=2021-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279790, encodeId=5d4412e97906f, content=<a href='/topic/show?id=265c66e50ea' target=_blank style='color:#2F92EE;'>#激光#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66750, encryptionId=265c66e50ea, topicName=激光)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4fd6156, createdName=oliver169, createdTime=Fri Sep 17 05:01:19 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1394127, encodeId=93c6139412e73, content=<a href='/topic/show?id=7b29e0460b1' target=_blank style='color:#2F92EE;'>#疤痕#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70460, encryptionId=7b29e0460b1, topicName=疤痕)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/qXbLjJB4FSzhQS3C5qQFMJkqicRIJFL6zHFwwhv0I95nzA6xicevQcEica0gk4A58UkbMMriadAgTY2b7N7Yd0ZsQg/132, createdBy=910c2500152, createdName=HinsMax, createdTime=Fri Sep 17 05:01:19 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1591685, encodeId=f1fb159168591, content=<a href='/topic/show?id=409d28835d6' target=_blank style='color:#2F92EE;'>#光疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28835, encryptionId=409d28835d6, topicName=光疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=477c17977507, createdName=fusion, createdTime=Fri Sep 17 05:01:19 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1611255, encodeId=6760161125539, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri Sep 17 05:01:19 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051503, encodeId=0a9610515038a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=821f2227826, createdName=DR.Fu SIR, createdTime=Wed Sep 15 15:41:15 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051512, encodeId=bb42105151249, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=2d785605234, createdName=ms4000000114765638, createdTime=Wed Sep 15 16:02:00 CST 2021, time=2021-09-15, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1878414, encodeId=2aac18e8414b9, content=<a href='/topic/show?id=c157696175' target=_blank style='color:#2F92EE;'>#ERS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6961, encryptionId=c157696175, topicName=ERS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e93e105, createdName=anminleiryan, createdTime=Wed Mar 02 13:01:19 CST 2022, time=2022-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1747907, encodeId=50a71e4790762, content=<a href='/topic/show?id=77d62883411' target=_blank style='color:#2F92EE;'>#光疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28834, encryptionId=77d62883411, topicName=光疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb1d35982112, createdName=俅侠, createdTime=Sat Dec 04 18:01:19 CST 2021, time=2021-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279790, encodeId=5d4412e97906f, content=<a href='/topic/show?id=265c66e50ea' target=_blank style='color:#2F92EE;'>#激光#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66750, encryptionId=265c66e50ea, topicName=激光)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4fd6156, createdName=oliver169, createdTime=Fri Sep 17 05:01:19 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1394127, encodeId=93c6139412e73, content=<a href='/topic/show?id=7b29e0460b1' target=_blank style='color:#2F92EE;'>#疤痕#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70460, encryptionId=7b29e0460b1, topicName=疤痕)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/qXbLjJB4FSzhQS3C5qQFMJkqicRIJFL6zHFwwhv0I95nzA6xicevQcEica0gk4A58UkbMMriadAgTY2b7N7Yd0ZsQg/132, createdBy=910c2500152, createdName=HinsMax, createdTime=Fri Sep 17 05:01:19 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1591685, encodeId=f1fb159168591, content=<a href='/topic/show?id=409d28835d6' target=_blank style='color:#2F92EE;'>#光疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28835, encryptionId=409d28835d6, topicName=光疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=477c17977507, createdName=fusion, createdTime=Fri Sep 17 05:01:19 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1611255, encodeId=6760161125539, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri Sep 17 05:01:19 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051503, encodeId=0a9610515038a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=821f2227826, createdName=DR.Fu SIR, createdTime=Wed Sep 15 15:41:15 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051512, encodeId=bb42105151249, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=2d785605234, createdName=ms4000000114765638, createdTime=Wed Sep 15 16:02:00 CST 2021, time=2021-09-15, status=1, ipAttribution=)]
    2021-09-15 DR.Fu SIR

    学习了

    0

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    2021-09-15 ms4000000114765638

    学习

    0

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