Stroke:睡眠呼吸暂停对房颤患者心脏栓塞风险的影响

2020-12-07 MedSci原创 MedSci原创

这些结果支持OSA相关的缺氧在预测AF患者发生心栓栓塞并发症(例如卒中)风险中的潜在作用。

精准确定房颤(AF)患者心脏栓塞风险对于预防卒中等结局至关重要。阻塞性睡眠呼吸暂停(OSA)是房颤和卒中已知的危险因素。近日,血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员旨在探讨OSA与AF患者心脏栓塞风险增加之间的可能联系。

研究人员评估了来自欧洲睡眠呼吸暂停数据库(ESADA)队列的数据,其中纳入了AF和OSA患者。研究人员分析了OSA严重程度和相关缺氧参数,如最低Spo2和4%氧去饱和指数。研究人员根据受试者CHA2DS2-VASc评分确定的心脏栓塞风险对患者进行分层。

最初的队列中有14646名患者,最终有363名患者被纳入分析。

睡眠中的低氧指标与CHA2DS2-VASc评分升高有关(对于低、中和高心血管疾病风险的个体,4%氧去饱和度指数分别为17.9、29.6和30.5次事件/小时,最低Spo2分别为81.2、77.8和77.5%,P<0.05)。

由此可见,这些结果支持OSA相关的缺氧在预测AF患者发生心栓栓塞并发症(例如卒中)风险中的潜在作用。

原始出处:

Martino F. Pengo,et al.Impact of Sleep Apnea on Cardioembolic Risk in Patients With Atrial Fibrillation Data From the ESADA Cohort.stroke.2020.https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.030285

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    2020-12-10 14701227m79暂无昵称

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    2020-12-08 ANNA1

    学习

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1989165, encodeId=89201989165cc, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Sat Nov 13 22:23:51 CST 2021, time=2021-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=906729, encodeId=bfdd906e2918, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7b245183802, createdName=14701227m79暂无昵称, createdTime=Thu Dec 10 15:58:57 CST 2020, time=2020-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596607, encodeId=4780159660e09, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Wed Dec 09 05:23:51 CST 2020, time=2020-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1614572, encodeId=a9d716145e229, content=<a href='/topic/show?id=64f95426122' target=_blank style='color:#2F92EE;'>#房颤患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54261, encryptionId=64f95426122, topicName=房颤患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=937e19519012, createdName=hittouch, createdTime=Wed Dec 09 05:23:51 CST 2020, time=2020-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=905882, encodeId=d020905882bd, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200831/fb689c3e816d4a64820d63f72073eef4/29c665e5fc1341a9ae58ecf5b979aef9.jpg, createdBy=7e215414767, createdName=ANNA1, createdTime=Tue Dec 08 07:48:31 CST 2020, time=2020-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031325, encodeId=ff681031325e0, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Mon Dec 07 17:23:51 CST 2020, time=2020-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=905725, encodeId=3a63905e25db, content=希望又对OSA的研究有更多成果。, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Mon Dec 07 14:54:42 CST 2020, time=2020-12-07, status=1, ipAttribution=)]
    2020-12-07 心介

    房颤,临床上碰到很多哦

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1989165, encodeId=89201989165cc, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Sat Nov 13 22:23:51 CST 2021, time=2021-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=906729, encodeId=bfdd906e2918, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7b245183802, createdName=14701227m79暂无昵称, createdTime=Thu Dec 10 15:58:57 CST 2020, time=2020-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596607, encodeId=4780159660e09, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Wed Dec 09 05:23:51 CST 2020, time=2020-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1614572, encodeId=a9d716145e229, content=<a href='/topic/show?id=64f95426122' target=_blank style='color:#2F92EE;'>#房颤患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54261, encryptionId=64f95426122, topicName=房颤患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=937e19519012, createdName=hittouch, createdTime=Wed Dec 09 05:23:51 CST 2020, time=2020-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=905882, encodeId=d020905882bd, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200831/fb689c3e816d4a64820d63f72073eef4/29c665e5fc1341a9ae58ecf5b979aef9.jpg, createdBy=7e215414767, createdName=ANNA1, createdTime=Tue Dec 08 07:48:31 CST 2020, time=2020-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031325, encodeId=ff681031325e0, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Mon Dec 07 17:23:51 CST 2020, time=2020-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=905725, encodeId=3a63905e25db, content=希望又对OSA的研究有更多成果。, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Mon Dec 07 14:54:42 CST 2020, time=2020-12-07, status=1, ipAttribution=)]
    2020-12-07 weigq

    希望又对OSA的研究有更多成果。

    0

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