Sci Rep:非小细胞肺癌患者使用术前营养控制状态评分(CONUT)预测术后肺部并发症

2020-07-29 xiangting MedSci原创

术前CONUT评分是手术切除NSCLC患者PPCs和1年死亡率的独立预测指标。

术后肺部并发症(PPCs)对手术效果有明显影响。这项研究调查了营养控制状态评分(CONUT)对非小细胞肺癌(NSCLC)患者肺切除后PPC的预测能力。

研究回顾性分析了2016年1月至2017年12月接受肺全切的922例NSCLC患者的数据。分析了PPCs的发生率和特征,并比较了PPCs各种预后模型的受试者工作特征(ROC)曲线。CONUT评分大于1被认为是CONUT评分高。

PPCs的总发生率为8.6%(n=79)。高CONUT组肺炎的比例明显升高(P<0.05)。CONUT的曲线下面积(AUC)(0.64)始终比其他预后模型大(预后营养指数(PNI):AUC=0.61,格拉斯哥预后评分(GPS):AUC=0.57,以及加泰罗尼亚外科患者呼吸风险评估(ARISCAT):AUC=0.54)。多因素分析确定了体重过轻[比值比(OR)= 4.57,P=0.002]和高CONUT评分(OR = 1.91,P=0.009)是PPCs的独立预后因素。高CONUT评分的1年死亡率明显升高(危险比= 7.97;95%置信区间1.78-35.59)。

术前CONUT评分是手术切除NSCLC患者PPCs和1年死亡率的独立预测指标。

原始出处:

Sang Chul Lee. Prediction of postoperative pulmonary complications using preoperative controlling nutritional status (CONUT) score in patients with resectable non-small cell lung cancer. Sci Rep. 24 July 2020.

 

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    2020-07-29 ms3000000449926787

    学习了,谢谢!

    0

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    2020-07-29 12543f43m99暂无昵称

    学习

    0

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