JAHA:出生体重与心力衰竭的关系

2019-05-04 xing.T 网络

由此可见,高出生体重与发生心脏衰竭的风险显著增加有关,与传统危险因素无关,并且有增加死亡风险的趋势。应该在年轻人中确定高出生体重史,以便对心力衰竭和老年人进行一级预防。

心力衰竭的传统危险因素-冠心病、高血压糖尿病、肥胖和吸烟-仅占病例的50%左右。因此,识别新的危险因素具有重要的公共卫生价值。由于高出生体重婴儿后期肥胖和糖尿病风险增加,这两者都是心力衰竭发生的危险因素,近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员试图评估ARIC(社区动脉粥样硬化风险)研究中高出生体重与心力衰竭之间的关系。

ARIC研究是一项基于社区的前瞻性研究,调查了15792名45至64岁的基线人群。出生早产或出生于双胞胎的研究参与者被排除在此分析之外,9820名参与者提供他们的出生体重类别(低、中、高)或确切的出生体重。

在调整人口统计学指标、危险因素和合并症的差异后,与中等出生体重相比,出生体重较高的个体发生心力衰竭的风险显著增加(风险比为1.27; 95%CI为1.05-1.54 [P=0.014])。与中等出生体重相比,较高出生体重的个体全因死亡率为1.16(95%CI为0.99-1.34; P=0.06)。较高出生体重与心肌梗死无关(风险比为1.06; 95%CI为0.84-1.34 [P=0.6])。

由此可见,高出生体重与发生心脏衰竭的风险显著增加有关,与传统危险因素无关,并且有增加死亡风险的趋势。应该在年轻人中确定高出生体重史,以便对心力衰竭和老年人进行一级预防

原始出处:

Abdirahim Rashid.et al.Association of High Birth Weight With Incident Heart Failure in the ARIC Study.JAHA.2019.https://www.ahajournals.org/doi/10.1161/JAHA.118.011524

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  1. [GetPortalCommentsPageByObjectIdResponse(id=365893, encodeId=a13f365893da, content=这个挺好,挺有意思!, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210124/2959859c08784950bc188459d8d7c2c1/3509ed0b3e3e4ca08f78e8a9232d2e4c.jpg, createdBy=24f61480129, createdName=小豁牙, createdTime=Wed May 08 05:28:57 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268133, encodeId=d806126813388, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Mon May 06 13:41:00 CST 2019, time=2019-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1440754, encodeId=5ff31440e54dc, content=<a href='/topic/show?id=f99e3142e4d' target=_blank style='color:#2F92EE;'>#出生体重#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31427, encryptionId=f99e3142e4d, topicName=出生体重)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5ffd4758992, createdName=ms9608593228839890, createdTime=Mon May 06 13:41:00 CST 2019, time=2019-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=365792, encodeId=00ce365e92cf, content=好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Mon May 06 06:00:09 CST 2019, time=2019-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=365728, encodeId=4939365e2837, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d551998554, createdName=1e1c07bdm01(暂无匿称), createdTime=Sun May 05 02:21:11 CST 2019, time=2019-05-05, status=1, ipAttribution=)]
    2019-05-08 小豁牙

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    0

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    2019-05-06 zhaohui6731
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  4. [GetPortalCommentsPageByObjectIdResponse(id=365893, encodeId=a13f365893da, content=这个挺好,挺有意思!, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210124/2959859c08784950bc188459d8d7c2c1/3509ed0b3e3e4ca08f78e8a9232d2e4c.jpg, createdBy=24f61480129, createdName=小豁牙, createdTime=Wed May 08 05:28:57 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268133, encodeId=d806126813388, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Mon May 06 13:41:00 CST 2019, time=2019-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1440754, encodeId=5ff31440e54dc, content=<a href='/topic/show?id=f99e3142e4d' target=_blank style='color:#2F92EE;'>#出生体重#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31427, encryptionId=f99e3142e4d, topicName=出生体重)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5ffd4758992, createdName=ms9608593228839890, createdTime=Mon May 06 13:41:00 CST 2019, time=2019-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=365792, encodeId=00ce365e92cf, content=好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Mon May 06 06:00:09 CST 2019, time=2019-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=365728, encodeId=4939365e2837, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d551998554, createdName=1e1c07bdm01(暂无匿称), createdTime=Sun May 05 02:21:11 CST 2019, time=2019-05-05, status=1, ipAttribution=)]
    2019-05-06 yjs木玉

    好好好好好好

    0

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