BMJ:慢性呼吸道疾病负担研究-1990-2017

2020-02-21 MedSci MedSci原创

研究认为,社会人口指数低地区的慢性呼吸道疾病负担较重,吸烟、环境污染和高BMI均是导致慢性呼吸道疾病死亡率和致残的重要因素

近日研究人员利用2017年全球疾病、伤害和风险因素负担研究数据,对1990-2017年间全球慢性呼吸道疾病死亡率和残疾调整寿命年(DALYs)进行了考察。

研究采用具有高斯分布的广义线性模型计算慢性呼吸道疾病年龄标准化死亡率变化百分比。根据社会人口指数对死亡率和伤残调整生命年进行分层并分析了慢性呼吸道疾病的危险因素。

从1990年到2017年,慢性呼吸系统疾病死亡总人数增加了18.0%,从1990年的332万增加到2017年的391万。慢性呼吸系统疾病的年龄标准化死亡率平均每年下降2.41%。在27年中,慢性阻塞性肺疾病(COPD 2.36%)和尘肺(2.56%)的死亡率年下降速度较慢,而间质性肺病和肺结节病(0.97%)的死亡率则有所上升。哮喘和尘肺的DALYs减少,而COPD、间质性肺病和肺结节病的DALYs增加。195个国家的死亡率和慢性呼吸道疾病造成的死亡率年变化差异很大。社会人口指数与COPD、尘肺和哮喘的死亡率之间存在负相关性。社会人口指数较低地区死亡率和Dalys较高。吸烟仍然是COPD和哮喘死亡的主要危险因素。在社会人口指数较低的地区,颗粒物污染是导致COPD死亡的主要因素。自2013年以来,高BMI已成为哮喘的主要危险因素。

研究认为,社会人口指数低地区的慢性呼吸道疾病负担较重,吸烟、环境污染和高BMI均是导致慢性呼吸道疾病死亡率和致残的重要因素。

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    2020-06-17 gaoxiaoe
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    2020-02-23 zhmscau
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过敏性鼻炎(AR)、哮喘、慢性阻塞性肺病(COPD)和鼻窦炎是常见的疾病,但是在亚太地区却鲜有研究。最近,有研究人员调查了这些呼吸道疾病在印度、韩国、马拉西亚、新加坡、泰国以及中国台湾的真实世界医疗模式情况。研究发现,总共筛选了13902名患者,7243(52%)名患者为AR(18%)、哮喘(18%)和COPD(7%)以及鼻窦炎(9%)。该7243名患者中的5250(72%)名患者符合研究的要求。