JAHA:感染性心内膜炎患者心脏瓣膜置换术使用和结局的性别差异

2021-10-11 MedSci原创 MedSci原创

尽管男性和女性感染性心内膜炎瓣膜手术的使用率有所增加,死亡率趋势有所改善。

关于性别对感染性心内膜炎患者瓣膜置换手术利用和结局不同影响的数据仅限于单中心和小样本患者群体。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员利用全国住院患者样本数据库来识别2004年至2015年期间出院诊断为感染性心内膜炎的患者,以评估按性别分层的感染性心内膜炎住院患者的特征和临床结局的差异。

研究人员还评估了12年间女性与男性心脏瓣膜置换术和个体瓣膜置换术的使用趋势,并比较了女性与男性手术治疗后的院内死亡率。

2004年1月至2015年9月,共有81942例感染性心内膜炎住院患者,其中女性占44.31%。女性不太可能接受整体心脏瓣膜置换术(6.92% vs. 12.12%)、主动脉瓣置换术(3.32% vs. 8.46%)、二尖瓣置换术(4.60% vs. 5.57%)以及联合主动脉瓣和二尖瓣置换术(0.85% vs. 1.81%),但院内死亡率相似。从2004年到2015年,心脏瓣膜置换术的总体发生率男性从11.76%上升到13.96%,女性从6.34%上升到9.26%,男性和女性的住院死亡率都有所下降。在接受瓣膜置换手术的患者中,女性的院内死亡率较高(9.94% vs. 6.99%,P<0.001)。

尽管男性和女性感染性心内膜炎瓣膜手术的使用率有所增加,死亡率趋势有所改善。但该研究的结果表明,与男性患者相比,感染性心内膜炎女性患者瓣膜手术并未充分利用,且存在治疗偏倚,该研究证明接受瓣膜手术的女性院内死亡率较高。

原始出处:

Agam Bansal.et al.Sex Differences in the Utilization and Outcomes of Cardiac Valve Replacement Surgery for Infective Endocarditis: Insights From the National Inpatient Sample.JAHA.2021.https://www.ahajournals.org/doi/full/10.1161/JAHA.121.021406

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  5. 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  6. 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encodeId=87461268646a5, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Wed Oct 13 12:25:12 CST 2021, time=2021-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1350761, encodeId=86611350e61b0, content=<a href='/topic/show?id=a32d508e8c3' target=_blank style='color:#2F92EE;'>#心内膜炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50878, encryptionId=a32d508e8c3, topicName=心内膜炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Oct 13 12:25:12 CST 2021, time=2021-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576819, encodeId=5f4815e681963, content=<a href='/topic/show?id=48fee966468' target=_blank style='color:#2F92EE;'>#置换术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79664, encryptionId=48fee966468, topicName=置换术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=054816326830, createdName=ms117281293605716, createdTime=Wed Oct 13 12:25:12 CST 2021, time=2021-10-13, status=1, ipAttribution=)]
    2021-11-02 yxch48
  7. 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    2021-10-14 Doctoryangbai

    女性感染性心内膜炎应该倍受重视

    0

  8. 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    2021-10-13 zhaohui6731
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