Modern Pathology:人工智能辅助能够显著改善病例学家对前列腺活检的格林森分级

2020-08-20 AlexYang MedSci原创

格林森评分是前列腺癌患者最重要的预后标记,但是受观察者的影响很大。基于深度学习的人工智能(AI)系统在格林森分级中能够达到病理学家水平。然而,该系统的表现性能在人工制品,异体组织或者其他异常存在的情况

格林森评分是前列腺癌患者最重要的预后标记,但是受观察者的影响很大。基于深度学习的人工智能(AI)系统在格林森分级中能够达到病理学家水平。然而,该系统的表现性能在人工制品,异体组织或者其他异常存在的情况下会有所降低。病理学家将他们的经验与AI系统的反馈结果整合能够产生协同效果,会优于单独的病理学家结果和系统结果。尽管人工智能非常火热,关于上述问题的文献却非常有限。

最近,有研究人员调查了AI协助分级前列腺活检的价值情况。研究共包括了14名观察者和160例活检样本,包括了AI协助和不协助两种情况。研究发现,使用AI时,专家组与专家参考标准的一致性显著增加(二次加权Cohen's kappa 0.799 vs. 0.872;p=0.019)。在一个包括87个病例的外部验证集中,专家组结果与国际前列腺病例专家组结果的一致性显著增加(二次加权Cohen's kappa 0.733 vs. 0.786; p=0.003)。在上述两个试验中,在小组水平上AI协助病理学家的表现要由于无协助的病理学家和单独的AI系统。

有无AI协助时的专家组表现

最后,研究人员指出,他们的结果表明了AI系统在格林森分级上的潜力,更重要的是,病理学家-AI系统能够产生有益的协同作用。

原始出处:

Wouter Bulten, Maschenka Balkenhol, Jean-Joël Awoumou Belinga et al. Artificial intelligence assistance significantly improves Gleason grading of prostate biopsies by pathologists. Modern Pathology . August 2020

 

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    2021-02-22 yb6560
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    2020-08-22 smlt2008
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    2020-08-20 ms3000000449926787

    牛,人工智能!

    0

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