触目惊心!一例静滴药物外渗造成的严重并发症!

2017-07-15 纳洛酮 中国护理管理

也许你有点不敢相信自己的眼睛,图片中,患者这只输液的手上出现的骨筋膜室综合症和张力性大疱,如此后果严重、令人触目惊心的并发症竟然是由于静脉输液药物外渗引起的!

也许你有点不敢相信自己的眼睛,图片中,患者这只输液的手上出现的骨筋膜室综合症和张力性大疱,如此后果严重、令人触目惊心的并发症竟然是由于静脉输液药物外渗引起的!

这是一位医护人员发出的图片,他(她)所提供给我们的信息,只有这张图,和“输液外渗造成的骨筋膜室综合症和张力性大疱”这几个又黑又冷又硬的大字。

这是一张足以让临床一线的医护人员敲响警钟,并引以为鉴的图片,我们今天把它晒出来,就是想让广大护理人员对静脉输液药物外渗这样的不良事件,引起足够的关注和重视。

《静脉治疗护理技术操作规范》中,将药物外渗定义为:静脉输液过程中,腐蚀性药液进入静脉管腔以外的周围组织。

什么是静脉输液中的腐蚀性药物?不外乎血管活性药、高渗药物、化疗药物、血管刺激性药物这几种。临床常用的高危药物有:

血管活性药:多巴胺、间羟胺、多巴酚丁胺、肾上腺素、垂体后叶素、去甲肾上腺素等。

高渗药:20%甘露醇、浓氯化钠、50%葡萄糖、脂肪乳、复方氨基酸、碳酸氢钠、3L营养液等。

化疗药:阿霉素、顺铂、奥沙利铂、环磷酰胺、氟尿嘧啶、长春碱类、氮芥、丝裂霉素、柔红霉素等。

药物外渗处理不当,可引起局部皮肤变化,表现为皮肤颜色变黑或起水疱,水疱破裂后,形成溃疡。严重者,须进行外科清创和植皮。尤其应该注意的是,部分患者可能不出现上述的症状,等到发现时,已发生皮肤组织受损,甚至丧失肢体功能。

药物外渗的临床表现

轻度:局部组织出现大片红肿,沿血管出现条索状的红线,局部肿痛。

重度:局部皮肤苍白继而出现水疱,严重者出现紫黑色,如不及时处理皮下组织坏死,形成溃疡,甚至累及深层组织。

如果上述这些高危药物发生外渗,且处置不当,很有可能发生图片中这样严重的后果!

护士在静脉输液时,要熟知药物的性状,严防外渗的,如若出现外渗,就是护理不良事件,处置不当,会造成外渗处组织坏死,甚至溃烂,易造成护理纠纷。尤其是一些化疗药物、血管活性药物时,一定要小心谨慎,做好必要的护理干预措施,严防药液外渗。

护理干预措施

(1)输注前告知

输注上述这些高危药物时,要向患者及家属说明注意事项,取得患方的配合。在血管选择上,避开关节等易“跑水”的部位,化疗、抢救时使用静脉留置针或深静脉置管,防止药物外渗。

(2)勤巡视勤观察

密切关注输注部位,认真听取患者主诉,不能单靠输液管内有无回血来判断。

(3)正确判断有无外渗

观察注射部位有无肿胀,如外渗,按压可有凹陷或有张力无弹性。询问患者有无胀痛。

(4)药物外渗的正确处理

◎发现药物外渗,立即停药!

◎药物对组织刺激性小、容易吸收的,可热敷,50%硫酸镁湿热敷,促进扩散吸收。

◎冷敷是为了抑制药物在细胞内代谢,但须在6h内进行,24h后热敷。但对长春新碱和血管活性药物则应早期采取保温、热敷,患肢抬高,以利局部肿胀的吸收。

◎局部封闭:0.9%Ns5ml+地塞米松+利多卡因,在红肿皮肤边缘呈点状或扇状封闭。边退边注射药物,先把外渗区周边封闭起来,Qd,持续3-5天。

◎针对性处理:血管收缩药,应用热敷,从而促进药物吸收,尽快消肿。高渗药,立即停药,冷敷,局部封闭。化疗药物,根据具体药物选用合适的拮抗剂。

◎水疱的处理:多发性小水疱注意保持水疱的完整性,避免摩擦和热敷,让水疱自然吸收;大疱,应在严格消毒后,用针头在水疱边缘穿刺,将水疱的液体吸收,情况严重的,应由伤口造口专科护士会诊,跟踪处理。

◎外科处理:保守疗法无效者,溃疡形成,请整形外科会诊处理。图片中已然形成骨筋膜室综合症和张力性大疱,已经到了外科住院治疗的指证,如不正确做出处理,会给患者造成不可弥补的损害。

骨筋膜室综合征一经确诊,应立即切开筋膜减压。早期彻底切开筋膜减压是防止肌肉和神经发生缺血性坏死的惟一有效方法。切不可等到出现5“P”体征后才行切开减压术,从而导致不可逆的缺血性肌挛缩。切开的皮肤一般多因张力过大而不能缝合。可用凡士林纱布松松填塞,外用无菌敷料包好,待消肿后行延期缝合,或应用游离皮片移植闭合伤口。切不可勉强缝合皮肤,失去切开减压的作用。

张力性水疱若不及时处理,水疱破裂后很容易引起感染。若单纯抽出水疱液体,则复发率比较高。处理原则:解除压迫,抬高患肢,避免磨擦,防止破裂。

◎发生外渗所致静脉炎的患肢,应抬高并禁止静脉注射,患肢无受压,经常按摩四肢,促进末梢循环。

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createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sat Jul 15 18:25:10 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222630, encodeId=82a022263055, content=好东西学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Sat Jul 15 17:05:46 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222611, encodeId=1f432226114f, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Sat Jul 15 14:42:44 CST 2017, time=2017-07-15, status=1, ipAttribution=)]
    2017-07-16 虈亣靌

    谢谢分享

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2019857, encodeId=5695201985e10, content=<a href='/topic/show?id=4aab8e719b4' target=_blank style='color:#2F92EE;'>#药物外渗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87719, encryptionId=4aab8e719b4, topicName=药物外渗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8dca2500075, createdName=396094184_42047355, createdTime=Thu Feb 01 09:03:00 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1757818, encodeId=f4c91e5781865, content=<a href='/topic/show?id=84ba49031f9' target=_blank style='color:#2F92EE;'>#并发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49031, encryptionId=84ba49031f9, topicName=并发)], attachment=null, authenticateStatus=null, createdAvatar=null, 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createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sat Jul 15 18:25:10 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222630, encodeId=82a022263055, content=好东西学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Sat Jul 15 17:05:46 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222611, encodeId=1f432226114f, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Sat Jul 15 14:42:44 CST 2017, time=2017-07-15, status=1, ipAttribution=)]
    2017-07-16 laoli

    受益匪浅,谢谢分享!

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2019857, encodeId=5695201985e10, content=<a href='/topic/show?id=4aab8e719b4' target=_blank style='color:#2F92EE;'>#药物外渗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87719, encryptionId=4aab8e719b4, topicName=药物外渗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8dca2500075, createdName=396094184_42047355, createdTime=Thu Feb 01 09:03:00 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1757818, encodeId=f4c91e5781865, content=<a href='/topic/show?id=84ba49031f9' target=_blank style='color:#2F92EE;'>#并发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49031, encryptionId=84ba49031f9, topicName=并发)], attachment=null, authenticateStatus=null, createdAvatar=null, 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createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sat Jul 15 18:25:10 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222630, encodeId=82a022263055, content=好东西学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Sat Jul 15 17:05:46 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222611, encodeId=1f432226114f, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Sat Jul 15 14:42:44 CST 2017, time=2017-07-15, status=1, ipAttribution=)]
    2017-07-16 蔬菜

    好内容,谢谢分享,学习了

    0

  6. 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createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sat Jul 15 18:25:10 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222630, encodeId=82a022263055, content=好东西学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Sat Jul 15 17:05:46 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222611, encodeId=1f432226114f, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Sat Jul 15 14:42:44 CST 2017, time=2017-07-15, status=1, ipAttribution=)]
    2017-07-16 松鼠上树

    学习了,谢谢分享,获益匪浅

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2019857, encodeId=5695201985e10, content=<a href='/topic/show?id=4aab8e719b4' target=_blank style='color:#2F92EE;'>#药物外渗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87719, encryptionId=4aab8e719b4, topicName=药物外渗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8dca2500075, createdName=396094184_42047355, createdTime=Thu Feb 01 09:03:00 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1757818, encodeId=f4c91e5781865, content=<a href='/topic/show?id=84ba49031f9' target=_blank style='color:#2F92EE;'>#并发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49031, encryptionId=84ba49031f9, topicName=并发)], attachment=null, authenticateStatus=null, createdAvatar=null, 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createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sat Jul 15 18:25:10 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222630, encodeId=82a022263055, content=好东西学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Sat Jul 15 17:05:46 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222611, encodeId=1f432226114f, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Sat Jul 15 14:42:44 CST 2017, time=2017-07-15, status=1, ipAttribution=)]
    2017-07-16 1861f45ec3m

    学习了,谢谢

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2019857, encodeId=5695201985e10, content=<a href='/topic/show?id=4aab8e719b4' target=_blank style='color:#2F92EE;'>#药物外渗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87719, encryptionId=4aab8e719b4, topicName=药物外渗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8dca2500075, createdName=396094184_42047355, createdTime=Thu Feb 01 09:03:00 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1757818, encodeId=f4c91e5781865, content=<a href='/topic/show?id=84ba49031f9' target=_blank style='color:#2F92EE;'>#并发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49031, encryptionId=84ba49031f9, topicName=并发)], attachment=null, authenticateStatus=null, createdAvatar=null, 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createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sat Jul 15 18:25:10 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222630, encodeId=82a022263055, content=好东西学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Sat Jul 15 17:05:46 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222611, encodeId=1f432226114f, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Sat Jul 15 14:42:44 CST 2017, time=2017-07-15, status=1, ipAttribution=)]
    2017-07-15 131****1460

    学习了受益匪浅。

    0

  9. 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createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/7gcDIibiafYAAXSicO2lQH9E54CZv1GXQ7mreyOcYAr602zBBR427zZNvyiamoNRwDblRdeGb4lz8QvGYxGarrkyOw/132, createdBy=bba82068573, createdName=松鼠上树, createdTime=Sun Jul 16 08:28:16 CST 2017, time=2017-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222769, encodeId=4f2c222e69bf, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=31062091081, createdName=1861f45ec3m, createdTime=Sun Jul 16 07:15:36 CST 2017, time=2017-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222647, encodeId=2af322264eae, content=学习了受益匪浅。, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sat Jul 15 18:25:10 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222630, encodeId=82a022263055, content=好东西学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Sat Jul 15 17:05:46 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222611, encodeId=1f432226114f, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Sat Jul 15 14:42:44 CST 2017, time=2017-07-15, status=1, ipAttribution=)]
    2017-07-15 thlabcde

    好东西学习了!

    0

  10. 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createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sat Jul 15 18:25:10 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222630, encodeId=82a022263055, content=好东西学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Sat Jul 15 17:05:46 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222611, encodeId=1f432226114f, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Sat Jul 15 14:42:44 CST 2017, time=2017-07-15, status=1, ipAttribution=)]
    2017-07-15 杨利洪

    学习了分享了

    0