J Spinal Disord Tech:术中减压范围增大和脊髓后移可导致C5神经根麻痹

2014-12-18 江涛 丁香园

C5神经根麻痹是颈椎减压术后以三角肌肌力下降为特征的常见术后并发症。有资料显示C5神经根麻痹的发病率在4.6%左右,后路椎板椎间孔切除术C5神经根麻痹的发病率有11.6%。椎板椎间孔切开术后常可引起C5神经根麻痹,但其发病机理了解甚少。 约翰霍普金斯大学医学院Bydon等对41位脊椎退行性疾病并进行了椎板椎间孔切开加椎体融合术的病人开展了回顾性临床研究,该研究最近发表在Spine杂志上。 41

C5神经根麻痹是颈椎减压术后以三角肌肌力下降为特征的常见术后并发症。有资料显示C5神经根麻痹的发病率在4.6%左右,后路椎板椎间孔切除术C5神经根麻痹的发病率有11.6%。椎板椎间孔切开术后常可引起C5神经根麻痹,但其发病机理了解甚少。

约翰霍普金斯大学医学院Bydon等对41位脊椎退行性疾病并进行了椎板椎间孔切开加椎体融合术的病人开展了回顾性临床研究,该研究最近发表在Spine杂志上。

41位病人中9位病人出现C5神经根麻痹,32位无C5神经根麻痹,试验采用了双盲的方法,根据术前和术后患者的影像(CT和MRI)分别测量了与C5神经根麻痹有关的4个影像参数:脊柱前凸曲率变化(测量Cobb角),硬膜的扩张(测量C5神经根水平的硬膜宽度),脊髓后移(测量脊髓前正中裂到椎管前方的距离),C5椎间孔的变化(测量术侧椎间孔宽度)。

QQ图片20141211222220.jpg

脊髓后移从术前0.16cm到术后0.31cm(相差0.15cm),脊柱前凸从术前38.88°到术后46.29°(相差7.41°),C5椎间孔的变化从术前0.17cm到术后0.28cm(相差0.11cm),硬膜的扩张从术前0.84cm到术后1.13cm(相差0.29cm)。4项参数术前和术后均发生了变化。

C5神经根麻痹和无C5神经根麻痹两组术前相比,脊柱前凸角(38.93°比38.87°),C5椎间孔宽度(0.16比0.17) ,硬膜宽度 (0.91比0.82),脊髓后移(0.19比0.15),两组之间术前均无统计学差异。

C5神经根麻痹和无C5神经根麻痹两组术前和术后相比,脊髓后移增加(0.32比0.10cm),C5椎间孔宽度(0.18比0.86),硬膜宽度 (0.52比0.23),有统计学差异。脊柱前凸角变化(7.45°比7.40°),无统计学差异。

结果显示,C5神经根麻痹与脊髓后移、C5椎间孔和硬膜宽度增大有统计学意义,而与脊柱前凸的矫正无统计学意义。

Bydon等认为椎体减压范围增大可导致硬脊膜扩张,引起脊髓后移,造成对C5神经根的牵拉,因此C5神经根麻痹的发生率越高。

有文章报道术中对C5神经根的损伤是造成术后C5神经根麻痹的原因,这一观点仍在争论。报道称术中神经监测可以降低神经损伤的发生率,因此Bydon等回顾性研究患者术中神经监测记录,但结果无明显差异。

Bydon等指出减压范围增大并不是C5神经根麻痹的直接危险因素,试验并不能证明两者之间有因果关系,但可以明确的是C5神经根麻痹与减压范围增大和脊髓后移有关,其原因可能是由于对C5神经根的牵拉造成的。

原始出处

Lian XF1, Xu JG, Zeng BF, Liu XK, Li H, Qiu ML, Yang EZ.Continuous irrigation and drainage for early postoperative deep wound infection after posterior instrumented spinal fusion.J Spinal Disord Tech. 2014 Dec;

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1652121, encodeId=9c911652121a9, content=<a href='/topic/show?id=13d01e24509' target=_blank style='color:#2F92EE;'>#TEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17245, encryptionId=13d01e24509, topicName=TEC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=852f24292001, createdName=shock_melon, createdTime=Mon Dec 29 03:51:00 CST 2014, time=2014-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1784374, encodeId=5dda1e84374cd, content=<a href='/topic/show?id=a727600194' target=_blank style='color:#2F92EE;'>#Disord#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6001, encryptionId=a727600194, topicName=Disord)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aad0444, createdName=cmsvly, createdTime=Wed Jul 29 11:51:00 CST 2015, time=2015-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20964, encodeId=266f20964c3, content=患OS这个疾病的高风险人群提供干预措施以避免不良预后和机械治疗措施, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sun Apr 12 07:54:00 CST 2015, time=2015-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011933, encodeId=06942011933e4, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sun Nov 22 17:51:00 CST 2015, time=2015-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1756292, encodeId=366c1e5629226, content=<a href='/topic/show?id=7414e433393' target=_blank style='color:#2F92EE;'>#神经根#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74333, encryptionId=7414e433393, topicName=神经根)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=806637100031, createdName=dzx0922901, createdTime=Thu Aug 20 04:51:00 CST 2015, time=2015-08-20, status=1, ipAttribution=)]
    2014-12-29 shock_melon
  2. [GetPortalCommentsPageByObjectIdResponse(id=1652121, encodeId=9c911652121a9, content=<a href='/topic/show?id=13d01e24509' target=_blank style='color:#2F92EE;'>#TEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17245, encryptionId=13d01e24509, topicName=TEC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=852f24292001, createdName=shock_melon, createdTime=Mon Dec 29 03:51:00 CST 2014, time=2014-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1784374, encodeId=5dda1e84374cd, content=<a href='/topic/show?id=a727600194' target=_blank style='color:#2F92EE;'>#Disord#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6001, encryptionId=a727600194, topicName=Disord)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aad0444, createdName=cmsvly, createdTime=Wed Jul 29 11:51:00 CST 2015, time=2015-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20964, encodeId=266f20964c3, content=患OS这个疾病的高风险人群提供干预措施以避免不良预后和机械治疗措施, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sun Apr 12 07:54:00 CST 2015, time=2015-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011933, encodeId=06942011933e4, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sun Nov 22 17:51:00 CST 2015, time=2015-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1756292, encodeId=366c1e5629226, content=<a href='/topic/show?id=7414e433393' target=_blank style='color:#2F92EE;'>#神经根#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74333, encryptionId=7414e433393, topicName=神经根)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=806637100031, createdName=dzx0922901, createdTime=Thu Aug 20 04:51:00 CST 2015, time=2015-08-20, status=1, ipAttribution=)]
    2015-07-29 cmsvly
  3. [GetPortalCommentsPageByObjectIdResponse(id=1652121, encodeId=9c911652121a9, content=<a href='/topic/show?id=13d01e24509' target=_blank style='color:#2F92EE;'>#TEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17245, encryptionId=13d01e24509, topicName=TEC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=852f24292001, createdName=shock_melon, createdTime=Mon Dec 29 03:51:00 CST 2014, time=2014-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1784374, encodeId=5dda1e84374cd, content=<a href='/topic/show?id=a727600194' target=_blank style='color:#2F92EE;'>#Disord#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6001, encryptionId=a727600194, topicName=Disord)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aad0444, createdName=cmsvly, createdTime=Wed Jul 29 11:51:00 CST 2015, time=2015-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20964, encodeId=266f20964c3, content=患OS这个疾病的高风险人群提供干预措施以避免不良预后和机械治疗措施, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sun Apr 12 07:54:00 CST 2015, time=2015-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011933, encodeId=06942011933e4, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sun Nov 22 17:51:00 CST 2015, time=2015-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1756292, encodeId=366c1e5629226, content=<a href='/topic/show?id=7414e433393' target=_blank style='color:#2F92EE;'>#神经根#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74333, encryptionId=7414e433393, topicName=神经根)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=806637100031, createdName=dzx0922901, createdTime=Thu Aug 20 04:51:00 CST 2015, time=2015-08-20, status=1, ipAttribution=)]
    2015-04-12 x35042875

    患OS这个疾病的高风险人群提供干预措施以避免不良预后和机械治疗措施

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1652121, encodeId=9c911652121a9, content=<a href='/topic/show?id=13d01e24509' target=_blank style='color:#2F92EE;'>#TEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17245, encryptionId=13d01e24509, topicName=TEC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=852f24292001, createdName=shock_melon, createdTime=Mon Dec 29 03:51:00 CST 2014, time=2014-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1784374, encodeId=5dda1e84374cd, content=<a href='/topic/show?id=a727600194' target=_blank style='color:#2F92EE;'>#Disord#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6001, encryptionId=a727600194, topicName=Disord)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aad0444, createdName=cmsvly, createdTime=Wed Jul 29 11:51:00 CST 2015, time=2015-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20964, encodeId=266f20964c3, content=患OS这个疾病的高风险人群提供干预措施以避免不良预后和机械治疗措施, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sun Apr 12 07:54:00 CST 2015, time=2015-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011933, encodeId=06942011933e4, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sun Nov 22 17:51:00 CST 2015, time=2015-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1756292, encodeId=366c1e5629226, content=<a href='/topic/show?id=7414e433393' target=_blank style='color:#2F92EE;'>#神经根#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74333, encryptionId=7414e433393, topicName=神经根)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=806637100031, createdName=dzx0922901, createdTime=Thu Aug 20 04:51:00 CST 2015, time=2015-08-20, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1652121, encodeId=9c911652121a9, content=<a href='/topic/show?id=13d01e24509' target=_blank style='color:#2F92EE;'>#TEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17245, encryptionId=13d01e24509, topicName=TEC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=852f24292001, createdName=shock_melon, createdTime=Mon Dec 29 03:51:00 CST 2014, time=2014-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1784374, encodeId=5dda1e84374cd, content=<a href='/topic/show?id=a727600194' target=_blank style='color:#2F92EE;'>#Disord#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6001, encryptionId=a727600194, topicName=Disord)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aad0444, createdName=cmsvly, createdTime=Wed Jul 29 11:51:00 CST 2015, time=2015-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20964, encodeId=266f20964c3, content=患OS这个疾病的高风险人群提供干预措施以避免不良预后和机械治疗措施, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sun Apr 12 07:54:00 CST 2015, time=2015-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011933, encodeId=06942011933e4, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sun Nov 22 17:51:00 CST 2015, time=2015-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1756292, encodeId=366c1e5629226, content=<a href='/topic/show?id=7414e433393' target=_blank style='color:#2F92EE;'>#神经根#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74333, encryptionId=7414e433393, topicName=神经根)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=806637100031, createdName=dzx0922901, createdTime=Thu Aug 20 04:51:00 CST 2015, time=2015-08-20, status=1, ipAttribution=)]

相关资讯

Spine J:椎体血管瘤硬膜外软组织肿块压迫会导致神经功能障碍

椎体血管瘤是一种比较常见的椎体良性肿瘤,组织发生为错构瘤,多发生于青壮年,以胸椎下段和腰椎上段多见,病理学表现为大量增生的毛细血管及扩张的血窦。椎体血管瘤以中青年多见,男性较多于女性。 出现症状的血管瘤均为年轻人,尤其是侵袭性椎体血管瘤,瘤体不仅在椎体内侵润,而且蔓延进入附近周围结构,常见的是侵袭到椎管内,从而导致脊髓、马尾、硬膜囊的压迫,而导致严重的神经功能障碍。为了进一步评价目前侵袭性椎体血

Spine J:颈后路单开门C5神经瘫的危险因素

颈后路椎板成型术为治疗多节段颈椎病广泛认可的手术方法,临床效果确实。但术后上肢瘫,特别是C5神经瘫,为颈后路椎板成型术相对常见的并发症。其原因可能有两个:一是神经根牵拉导致损伤;另一个为缺血和/或再灌注损伤导致的脊髓节段病变。然而,其主要原因尚有争论。 C5神经瘫的发生率报道为4.6%,不同研究中差别较大(0-30%)。因此,很有必要探讨C5神经瘫的危险因素。 中国北京北医三院骨科的学

Spine:腰椎内固定可致固定节段远端椎间孔及神经根压力升高

脊柱内固定自20世纪70年代描述以来,已广泛用于各种脊柱疾病的治疗,包括退变,创伤,肿瘤和畸形。椎弓根钉系统由后向前贯穿脊柱的三柱,可实现牢固内固定,不像椎板下钢丝和钩只固定后柱。但由于可能的置钉错误,而导致如术后根性症状,假关节和内固定失败。 术中椎弓根钉置钉通常以平片确定,包括正侧位,电视X光机或椎弓根壁的试探。有文献报道,术中拍片有较高的错判率,可误将错误置钉以为正确。尽管X光机可