Ann Rheum Dis:早期脊柱关节炎中椎骨骨折的发病率低

2018-11-05 xiangting MedSci原创

SpA中VF椎骨骨折的实际患病率和发病率低于既往研究的报道。

据报道脊柱关节炎(SpA)患者椎骨骨折(VFs)的风险升高。这项研究假设VFs患病率低于既往研究的报道,尤其是在早期SpA中。这项研究旨在评估早期中轴型SpA患者5年内影像学VFs的发病率。

DESIR队列纳入高度疑诊中轴型SpA的炎性背痛患者,该队列是这项研究的基础。DESIR队列的所有X光片均在一个中心实验室,由一名专业从事VFs诊断的研究人员按照Genant法进行评估。研究人员评估了基线及5年内VFs和椎体畸形的患病率和发病率。

432例患者接受了5年的X光检查(平均年龄34.3±8.7岁,女性占53%)。19例患者(4.4%)的VF诊断存在疑问,需要进行判定。13例患者(3.0%)出现好发性VFs,位于胸椎(12例为1级)。5年时,5例患者出现偶发性VF(1.15%);7例椎骨骨折,多部分位于胸椎(n=6/7)和1级(n=6/7)。

在DESIR队列中,早期SpA患者VFs的患病率和发病率低(分别为3.0%和1.15%)。这证实了研究假设,即SpA中VF椎骨骨折的实际患病率和发病率低于既往研究的报道。

原始出处:

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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Mon Nov 05 12:06:11 CST 2018, time=2018-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=351615, encodeId=dba23516151f, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Mon Nov 05 12:06:05 CST 2018, time=2018-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=351614, encodeId=7faa35161489, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Mon Nov 05 12:06:02 CST 2018, time=2018-11-05, status=1, ipAttribution=)]
    2018-11-07 lmm397
  5. 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likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Mon Nov 05 12:06:02 CST 2018, time=2018-11-05, status=1, ipAttribution=)]
    2018-11-05 Y—xianghai

    学习了长知识

    0

  6. 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likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Mon Nov 05 12:06:02 CST 2018, time=2018-11-05, status=1, ipAttribution=)]
    2018-11-05 Y—xianghai

    学习了长知识

    0

  7. 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    2018-11-05 Y—xianghai

    学习了长知识

    0

  8. 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likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Mon Nov 05 12:06:02 CST 2018, time=2018-11-05, status=1, ipAttribution=)]
    2018-11-05 Y—xianghai

    学习了长知识

    0

  9. 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    2018-11-05 Y—xianghai

    学习了长知识

    0

  10. 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likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Mon Nov 05 12:06:02 CST 2018, time=2018-11-05, status=1, ipAttribution=)]
    2018-11-05 Y—xianghai

    学习了长知识

    0

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