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再生元抗体鸡尾酒REGN-COV2治疗特朗普新冠病毒感染，研究数据全在这里！

2020-10-03 Armstrong Armstrong

特朗普新冠病毒
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2020年9月29日，再生元公布新冠治疗抗体鸡尾酒REGN-COV2治疗非住院患者的积极临床数据。REGN-COV2可以显著降低病毒滴度，改善临床症状。

2020年9月29日，再生元公布新冠治疗抗体鸡尾酒REGN-COV2治疗非住院患者的积极临床数据。REGN-COV2可以显著降低病毒滴度，改善临床症状。

治疗之前，患者中41%患者为新冠病毒抗体阳性，45%患者为新冠病毒抗体阴性，14%患者未知。

新冠病毒抗体阳性患者体内病毒滴度更低，比抗体阴性患者的滴度低3-4个数量级。

安慰剂组，抗体阳性患者比抗体阴性患者缓解更快（7天 vs 13天）。

患者被1:1:1分组到高剂量组（8g）、低剂量组（2.4g）和安慰剂组。

REGN-COV2可以显著降低病毒滴度，基线病毒滴度高的患者降低幅度更大。

REGN-CoV2可以显著缩短临床缓解的时间。

对于病毒滴度高的患者，临床改善就更为明显。

REGN-CoV2两种抗体组分的半衰期分别为18-21天、24-25天。

REGN-COV2的耐受性良好。

总结

REGN-CoV2可以显著降低病毒滴度，对于血清抗体阴性的患者临床改善更为明显。这些数据表明，REGN-CoV2达到了设计目的，接下来可以期待其在治疗新冠肺炎住院患者的临床数据。

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    2021-08-12 鹅不吃草

    学习

    0

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    2021-01-09 zb1235672

    学习了

    0

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    2021-04-28 doctor-chen9582

    #研究数据#

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    2020-10-05 qblt

    #鸡尾酒#

    0

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    2020-10-03 公卫新人

    新冠肺炎，疫情何时才能消失

    0

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    2020-10-03 lovetcm

    #再生元#明天美股再生元，开盘会涨40%！！#特朗普#感染#新冠病毒#后，为什么没有选择#瑞德西韦#，而是选择了再生元这个抗体鸡尾酒疗法？

    1

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