JACC:吃坚果,活得长!21万人20年随访研究证实,每周吃五次坚果可降低冠心病风险

2017-11-15 谭硕 奇点网

虽说好吃,但杏仁、核桃这些坚果在人们的固有印象中都背着“油多”的标签,在三高已成家常便饭的年代,口腹之欲是不是要给身体健康让路呢?科学家们告诉你:No!每天适量吃点坚果,反倒可以降低冠心病等严重心血管疾病的发病风险!

虽说好吃,但杏仁、核桃这些坚果在人们的固有印象中都背着“油多”的标签,在三高已成家常便饭的年代,口腹之欲是不是要给身体健康让路呢?科学家们告诉你:No!每天适量吃点坚果,反倒可以降低冠心病等严重心血管疾病的发病风险!

11月14日的心血管顶级期刊《美国心脏病学会杂志》(JACC)上,哈佛大学陈曾熙公共卫生学院和医学院的研究人员发布了一项涵盖超过20万人的大型队列研究结果:每周摄入坚果5次(每次28克,即1盎司,下文简称1份)以上的人群,心血管疾病的发病风险较不吃坚果的人群降低14%,冠心病风险降低可以达到20%,以冠心病庞大的患者群体和潜在患者数量而言,这一效果已经相当惊人!

在小编看来,以冠心病和脑卒中为首的心脑血管疾病,凶残程度绝不亚于让人闻风丧胆的癌症军团。如果各大医院心内科常年爆满的状态还不足以解释,那就直接上数据吧:据全球疾病负担研究组(GBD Study)2017年公布的最新数据,缺血性心脏病已成为全球导致寿命损失最多的疾病,而冠心病占到缺血性心脏病的90%以上!在中国,脑卒中和缺血性心脏病分别是致死人数最多和第二多的疾病,连肺癌、肝癌这些大魔王,也要在冠心病面前甘拜下风。
 
磨牙吮血,杀人如麻,用来形容心脑血管疾病并不夸张
 
为了预防这种健康大敌杀上门,近年来的膳食指南也开始逐渐向植物类食物倾斜,富含不饱和脂肪酸、膳食纤维、矿物质等营养成分的坚果作用被再次重视,榛子、核桃等坚果预防心血管疾病的作用还得到了临床试验的证实。不过这些研究大多关注的是坚果总摄入量,具体应该吃哪些坚果,怎样去吃,还仍然莫衷一是。
 
以橄榄油和核桃、榛子等坚果摄入为代表的地中海饮食(Mediterranean Diet)能起到预防心脑血管疾病的作用,相关临床试验曾在2013年登上过《新英格兰医学杂志》
 
为了消除这些未知,哈佛大学的研究人员对美国三项长期大型队列研究——护士健康研究(NHS)及其二期(NHS II)和卫生专业人员随访研究(HPFS)的资料进行了筛选,衡量的心血管事件则主要为致命性心肌梗死、中风和心血管原因死亡。本次研究最终涵盖了21万人(超3/4为女性),也可谓兴师动众了,涉及的坚果则主要分为花生、核桃和杏仁等其他树生坚果三类。
 
在中位时间超过20年的随访后,研究人员最终记录到的冠心病病例和中风病例分别为8390例和5910例。调整了年龄、性别、家族史、吸烟状况、饮食、基础血脂等多种因素后,研究人员发现,比起那些基本不吃坚果的人,每周摄入1份坚果5次以上的人群,心血管疾病和冠心病风险都会下降,而且下降程度还是随坚果的摄入量多多益善的,每多吃1份坚果,两项风险就会下降6%和13%!


不同种类坚果在三项队列研究中分别带来的疾病风险下降,核桃一枝独秀
 
进一步的分析显示,核桃在坚果群中可以说效果拔群,每周只要吃1份核桃,就能使心血管疾病、冠心病和中风的风险分别降低19%、21%和17%,是唯一“三项全能”且明显降低了中风风险的坚果,补脑之名并非虚传。虽说花生因为可以用去榨油而被不少人“歧视”,但它在降低心血管疾病风险上也有着不错的效果。
 
本次的研究用大数据印证了此前诸多关于坚果摄入有益健康的研究,论文的第一作者Marta Guasch-Ferre博士表示,这一研究支持了将多种坚果作为“健康饮食模式”向人群大范围推广,预防多种慢性疾病的做法,而同期配发的评论文章就说得更加直接了,“吃坚果,活得长,未经加工的坚果也许可以加到饮食中作为天然的健康胶囊,让我们避免心血管疾病,健康地老去。”
 

论文第一作者Marta Guasch-Ferre博士
 
前不久,《柳叶刀》上关于高脂饮食也许更有益健康的论文:柳叶刀:太颠覆认知,18国13万人研究显示,高脂饮食竟然可以降低全因死亡风险; 碳水化合物摄入量高全因死亡风险增加近30%曾引起一阵热议,当时奇点糕就觉得,如果多摄入的是健康的脂肪,那的确很合逻辑。健康脂肪哪里找呢?坚果还真是个好来源,看来今后小编的饮食模式要向松鼠看齐了…… 

原始出处:Marta Guasch-Ferré, Xiaoran Liu, Vasanti S. Malik, et al. Nut Consumption and Risk of Cardiovascular Disease. JACC(2017).

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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Fri Nov 17 09:21:20 CST 2017, time=2017-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261685, encodeId=f5852616851b, content=阅读.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Thu Nov 16 09:49:58 CST 2017, time=2017-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261675, encodeId=dc722616e5dc, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, 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    2018-01-16 hbwxf
  4. 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    2017-11-20 大爰

    学习了谢谢分享!!

    0

  5. 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  6. 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    2017-11-17 大爰

    学习了谢谢分享!!

    0

  7. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Fri Nov 17 09:21:20 CST 2017, time=2017-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261685, encodeId=f5852616851b, content=阅读.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Thu Nov 16 09:49:58 CST 2017, time=2017-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261675, encodeId=dc722616e5dc, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Thu Nov 16 09:30:06 CST 2017, time=2017-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261670, encodeId=d9532616e0f2, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Thu Nov 16 09:29:28 CST 2017, time=2017-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261663, encodeId=bf5326166324, content=是很好的学习材料.不错.以后会多学习., beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, 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    2017-11-16 明天会更好!

    阅读.谢谢分享.

    0

  8. 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authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Thu Nov 16 08:41:23 CST 2017, time=2017-11-16, status=1, ipAttribution=)]
    2017-11-16 戒馋,懒,贪

    谢谢分享

    0

  9. 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    2017-11-16 yfjms

    学习

    0

  10. 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authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Thu Nov 16 08:41:23 CST 2017, time=2017-11-16, status=1, ipAttribution=)]
    2017-11-16 李东泽

    是很好的学习材料.不错.以后会多学习.

    0

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