国药中生发布新冠灭活疫苗III期临床期中分析结果,保护效力79.34%附点评:

2020-12-30 国药中生 国药中生

梅斯医学评:

梅斯医学评:

这是经过科学评估的结果,是可信的,真实的,有说服力的。此前报道所谓接种数万人,出国后无一感染等,都是“新闻报道”,不符合科学事实。

国药中生采用的是灭活疫苗技术,从技术角度上说,确实较mRNA疫苗(辉瑞和Moderna疫苗)落后,效果差一些是正常的。事实上,其它灭活疫苗,其病毒防护效果一般均在50-80%之间,很少有灭活疫苗防护超过80%的(包括流感疫苗,麻疹疫苗等等)。此次国药中生的疫苗效果在79.34%(当然,目前仍是期中分析结果,最终结果需要等待完整结果),已经是灭活疫苗的极限效果了,确实很难与mRNA疫苗防护达到95%相比。

总之,我们不必自傲,也不必自卑。疫苗的技术在不断升级,国内的疫苗技术整体与国际上还有相当大的差距,这是需要承认的事实。但是,就国内的病毒流行而言,国药中生的疫苗预防效果已经能达到很好的疗效了。而且国内疫苗技术也在不断进步!

当然,从科学角度上,等3期数据完全公布后,还要关注中和抗体的滴度,能否达到真正抗病毒的标准,以及多大比例人虽然产生了中和抗体,但是保护力量可能不够。以及产生的抗体能在体内维持多长时间,这些数据对于疫苗的接种,以及新冠接下来的防控都是十分重要的。

以下是报道:

今日(12月30日)国药集团中国生物经统计分析,新冠病毒灭活疫苗Ⅲ期临床试验期中分析数据结果显示:

国药集团中国生物北京公司新冠病毒灭活疫苗接种后安全性良好,免疫程序两针接种后,疫苗组接种者均产生高滴度抗体,中和抗体阳转率为99.52%,疫苗针对由新冠病毒感染引起的疾病(COVID-19)的保护效力为79.34%,

数据结果达到世界卫生组织相关技术标准及国家药监局印发的《新型冠状病毒预防用疫苗临床评价指导原则(试行)》中相关标准要求。目前,国药集团中国生物北京公司已正式向国家药监局提交附条件上市申请。

来源:国药集团中国生物北京公司官网

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    2021-02-16 juliusluan78
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createdName=ms9000001905793691, createdTime=Sun Jan 03 11:52:39 CST 2021, time=2021-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1524910, encodeId=6a2f1524910fa, content=<a href='/topic/show?id=4ba395994d' target=_blank style='color:#2F92EE;'>#II期临床#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9599, encryptionId=4ba395994d, topicName=II期临床)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=139811614978, createdName=guihongzh, createdTime=Fri Jan 01 05:58:33 CST 2021, time=2021-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1594847, encodeId=fe38159484ebb, content=<a href='/topic/show?id=b317956200' target=_blank style='color:#2F92EE;'>#III期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9562, encryptionId=b317956200, topicName=III期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Fri Jan 01 05:58:33 CST 2021, time=2021-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=912583, encodeId=1bba912583a7, content=优先接种人群都是免费的, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1cbf5448904, createdName=ms3000001417319363, createdTime=Thu Dec 31 15:16:53 CST 2020, time=2020-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028927, encodeId=f461102892e8d, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Wed Dec 30 17:58:33 CST 2020, time=2020-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=912194, encodeId=32f191219437, content=<a href='/topic/show?id=4dbd580630b' target=_blank style='color:#2F92EE;'>#新冠疫苗#</a>,这是公开的结果, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58063, encryptionId=4dbd580630b, topicName=新冠疫苗)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=lifefamily, createdTime=Wed Dec 30 15:44:02 CST 2020, time=2020-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=912191, encodeId=065d91219188, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200902/602d5f75ac2f4ff2ae550d077f508b79/049644e183b14188a59de0cfe50365dc.jpg, createdBy=0df05415219, createdName=ms8000001801586899, createdTime=Wed Dec 30 15:40:23 CST 2020, time=2020-12-30, status=1, ipAttribution=)]
    2021-01-03 ms9000001905793691

    好好学习

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1653142, encodeId=ea891653142a1, content=<a href='/topic/show?id=5b011018e07' target=_blank style='color:#2F92EE;'>#I期临床#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10187, encryptionId=5b011018e07, topicName=I期临床)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fc1f24335670, createdName=医生2402, createdTime=Wed Oct 27 17:58:33 CST 2021, time=2021-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2078848, encodeId=660120e8848b1, content=<a href='/topic/show?id=f48865242bb' target=_blank style='color:#2F92EE;'>#活疫苗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65242, encryptionId=f48865242bb, topicName=活疫苗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4aa106, 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createdName=ms9000001905793691, createdTime=Sun Jan 03 11:52:39 CST 2021, time=2021-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1524910, encodeId=6a2f1524910fa, content=<a href='/topic/show?id=4ba395994d' target=_blank style='color:#2F92EE;'>#II期临床#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9599, encryptionId=4ba395994d, topicName=II期临床)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=139811614978, createdName=guihongzh, createdTime=Fri Jan 01 05:58:33 CST 2021, time=2021-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1594847, encodeId=fe38159484ebb, content=<a href='/topic/show?id=b317956200' target=_blank style='color:#2F92EE;'>#III期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9562, encryptionId=b317956200, topicName=III期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Fri Jan 01 05:58:33 CST 2021, time=2021-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=912583, encodeId=1bba912583a7, content=优先接种人群都是免费的, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1cbf5448904, createdName=ms3000001417319363, createdTime=Thu Dec 31 15:16:53 CST 2020, time=2020-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028927, encodeId=f461102892e8d, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Wed Dec 30 17:58:33 CST 2020, time=2020-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=912194, encodeId=32f191219437, content=<a href='/topic/show?id=4dbd580630b' target=_blank style='color:#2F92EE;'>#新冠疫苗#</a>,这是公开的结果, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58063, encryptionId=4dbd580630b, topicName=新冠疫苗)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=lifefamily, createdTime=Wed Dec 30 15:44:02 CST 2020, time=2020-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=912191, encodeId=065d91219188, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200902/602d5f75ac2f4ff2ae550d077f508b79/049644e183b14188a59de0cfe50365dc.jpg, createdBy=0df05415219, createdName=ms8000001801586899, createdTime=Wed Dec 30 15:40:23 CST 2020, time=2020-12-30, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1653142, encodeId=ea891653142a1, content=<a href='/topic/show?id=5b011018e07' target=_blank style='color:#2F92EE;'>#I期临床#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10187, encryptionId=5b011018e07, topicName=I期临床)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fc1f24335670, createdName=医生2402, createdTime=Wed Oct 27 17:58:33 CST 2021, time=2021-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2078848, encodeId=660120e8848b1, content=<a href='/topic/show?id=f48865242bb' target=_blank style='color:#2F92EE;'>#活疫苗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65242, encryptionId=f48865242bb, topicName=活疫苗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4aa106, 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encryptionId=b317956200, topicName=III期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Fri Jan 01 05:58:33 CST 2021, time=2021-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=912583, encodeId=1bba912583a7, content=优先接种人群都是免费的, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1cbf5448904, createdName=ms3000001417319363, createdTime=Thu Dec 31 15:16:53 CST 2020, time=2020-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028927, encodeId=f461102892e8d, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, 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authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200902/602d5f75ac2f4ff2ae550d077f508b79/049644e183b14188a59de0cfe50365dc.jpg, createdBy=0df05415219, createdName=ms8000001801586899, createdTime=Wed Dec 30 15:40:23 CST 2020, time=2020-12-30, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1653142, encodeId=ea891653142a1, content=<a href='/topic/show?id=5b011018e07' target=_blank style='color:#2F92EE;'>#I期临床#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10187, encryptionId=5b011018e07, topicName=I期临床)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fc1f24335670, createdName=医生2402, createdTime=Wed Oct 27 17:58:33 CST 2021, time=2021-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2078848, encodeId=660120e8848b1, content=<a href='/topic/show?id=f48865242bb' target=_blank style='color:#2F92EE;'>#活疫苗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65242, encryptionId=f48865242bb, topicName=活疫苗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4aa106, 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createdName=ms9000001905793691, createdTime=Sun Jan 03 11:52:39 CST 2021, time=2021-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1524910, encodeId=6a2f1524910fa, content=<a href='/topic/show?id=4ba395994d' target=_blank style='color:#2F92EE;'>#II期临床#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9599, encryptionId=4ba395994d, topicName=II期临床)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=139811614978, createdName=guihongzh, createdTime=Fri Jan 01 05:58:33 CST 2021, time=2021-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1594847, encodeId=fe38159484ebb, content=<a href='/topic/show?id=b317956200' target=_blank style='color:#2F92EE;'>#III期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9562, encryptionId=b317956200, topicName=III期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Fri Jan 01 05:58:33 CST 2021, time=2021-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=912583, encodeId=1bba912583a7, content=优先接种人群都是免费的, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1cbf5448904, createdName=ms3000001417319363, createdTime=Thu Dec 31 15:16:53 CST 2020, time=2020-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028927, encodeId=f461102892e8d, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, 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authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200902/602d5f75ac2f4ff2ae550d077f508b79/049644e183b14188a59de0cfe50365dc.jpg, createdBy=0df05415219, createdName=ms8000001801586899, createdTime=Wed Dec 30 15:40:23 CST 2020, time=2020-12-30, status=1, ipAttribution=)]
    2020-12-31 ms3000001417319363

    优先接种人群都是免费的

    0

  8. 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encryptionId=b317956200, topicName=III期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Fri Jan 01 05:58:33 CST 2021, time=2021-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=912583, encodeId=1bba912583a7, content=优先接种人群都是免费的, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1cbf5448904, createdName=ms3000001417319363, createdTime=Thu Dec 31 15:16:53 CST 2020, time=2020-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028927, encodeId=f461102892e8d, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Wed Dec 30 17:58:33 CST 2020, time=2020-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=912194, encodeId=32f191219437, content=<a href='/topic/show?id=4dbd580630b' target=_blank style='color:#2F92EE;'>#新冠疫苗#</a>,这是公开的结果, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58063, encryptionId=4dbd580630b, topicName=新冠疫苗)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=lifefamily, createdTime=Wed Dec 30 15:44:02 CST 2020, time=2020-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=912191, encodeId=065d91219188, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200902/602d5f75ac2f4ff2ae550d077f508b79/049644e183b14188a59de0cfe50365dc.jpg, createdBy=0df05415219, createdName=ms8000001801586899, createdTime=Wed Dec 30 15:40:23 CST 2020, time=2020-12-30, status=1, ipAttribution=)]
    2020-12-30 公卫新人

    新冠肺炎,疫情何时才能消失

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1653142, encodeId=ea891653142a1, content=<a href='/topic/show?id=5b011018e07' target=_blank style='color:#2F92EE;'>#I期临床#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10187, encryptionId=5b011018e07, topicName=I期临床)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fc1f24335670, createdName=医生2402, createdTime=Wed Oct 27 17:58:33 CST 2021, time=2021-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2078848, encodeId=660120e8848b1, content=<a href='/topic/show?id=f48865242bb' target=_blank style='color:#2F92EE;'>#活疫苗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65242, encryptionId=f48865242bb, topicName=活疫苗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4aa106, 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createdName=ms9000001905793691, createdTime=Sun Jan 03 11:52:39 CST 2021, time=2021-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1524910, encodeId=6a2f1524910fa, content=<a href='/topic/show?id=4ba395994d' target=_blank style='color:#2F92EE;'>#II期临床#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9599, encryptionId=4ba395994d, topicName=II期临床)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=139811614978, createdName=guihongzh, createdTime=Fri Jan 01 05:58:33 CST 2021, time=2021-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1594847, encodeId=fe38159484ebb, content=<a href='/topic/show?id=b317956200' target=_blank style='color:#2F92EE;'>#III期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9562, encryptionId=b317956200, topicName=III期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Fri Jan 01 05:58:33 CST 2021, time=2021-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=912583, encodeId=1bba912583a7, content=优先接种人群都是免费的, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1cbf5448904, createdName=ms3000001417319363, createdTime=Thu Dec 31 15:16:53 CST 2020, time=2020-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028927, encodeId=f461102892e8d, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, 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authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200902/602d5f75ac2f4ff2ae550d077f508b79/049644e183b14188a59de0cfe50365dc.jpg, createdBy=0df05415219, createdName=ms8000001801586899, createdTime=Wed Dec 30 15:40:23 CST 2020, time=2020-12-30, status=1, ipAttribution=)]
    2020-12-30 lifefamily

    #新冠疫苗#,这是公开的结果

    0

  10. 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    2020-12-30 ms8000001801586899

    0

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