Radiology:CTA测算门静脉压力梯度来非侵入性诊断门静脉高压

2019-06-05 shaosai MedSci原创

本研究旨在建立并验证评价基于CT血管造影图像肝门静脉压力梯度(HVPG)计算机模型(虚拟HVPG)在非侵入性诊断肝硬化患者门静脉高压的价值。

本研究旨在建立并验证评价基于CT血管造影图像肝门静脉压力梯度(HVPG)计算机模型(虚拟HVPG)在非侵入性诊断肝硬化患者门静脉高压的价值。

本研究共纳入了102例受试者,不同病因所致肝硬化患者行经颈静脉HVPG测量、多普勒US和CT血管造影。利用3D重建模型和计算机流量动态算法建立虚拟HVPG。

结果为,在训练组(n=29),虚拟HVPG在预测临床显着门静脉高压(SCPG)的ROC曲线下面积为0.83 (95% CI: 0.58, 1.00)。该诊断能力在验证组得到验证,曲线下面积为0.89 (95% CI: 0.81, 0.96)。组间和组内阅片者一致性分别为0.88、0.96,表明虚拟HVPG指标具有良好可重复性。虚拟HVPG和侵入性HVPG间具有良好的相关性(R = 0.61, P < .001),以低于7.3 mm Hg排除CSPH,以13.0 mm Hg诊断CSPH。

本研究表明,虚拟肝门静脉压力梯度(HVPG)计算机模型表明其与侵入性HVPG具有良好相关性。虚拟HVPG同时对非侵入性诊断肝硬化患者临床显着门静脉高压具有较高价值。

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    2019-06-20 fusion
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    2019-09-10 windight
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    2019-06-09 1ddf0692m34(暂无匿称)

    学习了,谢谢分享

    0

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以前的随机研究显示血管内治疗(EVT)能够改善大血管闭塞性急性缺血性卒中患者的预后。这些关键随机试验的 meta分析显示随着治疗延迟的增加,EVT 的获益呈线性下降,但是前7.3h 内仍然能够显着获益。不过,大部分试验都是采用了 CT/CTA作为筛选患者的标准,比如 ASPECTS 评分、灌注 CT 或 CTA 的侧枝状态。

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研究认为,CTA联合标准治疗可显著降低稳定性胸痛患者冠心病死亡及非致死性心肌梗死发病风险

Radiology:冠脉周围脂肪沉积是急性斑块破裂及冠状动脉夹层的标识物

本研究旨在评价怀疑急性冠脉综合征(ACS)患者冠状动脉CTA上血管周围脂肪沉积的发生率及影响,并将结果发表在Radiology上。

Radiology:冠状动脉CTA血流储备分数评价新方法!

本研究旨在比较基于计算流体动力学来源的冠状动脉CTA血流储备分数(FFR)(FFRCFD)和基于机器学习算法的冠状动脉CTA得到的FFR(FFRML)两种技术方法的价值,并将结果发表在Radiology上。

Heart:CT冠脉造影在非心脏手术前风险分层中的应用

CTA上CAD的严重性和程度增加了非心脏手术患者围手术期MACE的风险。