Semin Arthritis Rheu:与常规的皮肌炎恶性肿瘤筛查相比,PET的患者花费更少

2018-11-18 xiangting MedSci原创

对保险公司而言,全身PET-CT的成本高于常规测试,但患者的自付费用较低。

皮肌炎(DM)与恶性肿瘤和间质性肺病相关。许多与DM相关的恶性肿瘤不是发生在全国指南规定常规筛查的器官中;因此,最佳的筛选方式仍存在争议。正电子发射断层扫描(PET)已被推荐作为更复杂筛查测试的单一研究替代方案,并在检测间质性肺病的进展中也有价值。对PET筛查的批判主要集中在成本和辐射暴露上。

这项研究旨在将PET及其变体的成本与常规恶性肿瘤筛查进行比较,并回顾有关PET中的辐射暴露问题。

研究包括4种PET变体和PET-CT。常规的筛查测试定义为无增强腹部和盆腔CT、无增强胸部CT、CEA、CA19.9、PSA(男性)、乳房X线摄影术(女性)、经阴道超声(女性)、细胞病理学(女性)和CA125(女性)。市场扫描?商业索赔和患者数据库,是一个来自5300万美国人的私人保险理赔数据集合,研究人员检索了该数据库2005至2014年每个测试的每个实例,并记录了每种测试的平均通胀调整后成本。将PET变体的保险公司平均总成本和患者平均自付费用与常规测试成本进行比较。另外,还评估了同一时期肺功能测试(PFT)的成本。

从2005年到2014年,PET的平均通胀调整后成本呈下降趋势,但PET-CT的平均成本呈上升趋势。男性和女性全身PET-CT的保险公司平均总成本分别比常规测试成本高出730.70美元和537.62美元。男性和女性全身PET-CT的患者自付费用分别比常规测试成本低了109.82美元和111.33美元。PFT的平均总成本为205.02美元。

对保险公司而言,全身PET-CT的成本高于常规测试,但患者的自付费用较低。PET-CT在检测和监测DM患者的间质性肺病进展方面具有额外价值。需要更多关于PET-CT检测DM患者恶性肿瘤的数据;然而成本差异比预期的小,表明在某些患者中单次扫描可作为常规筛查的合理替代方案。

原始出处:

Avery Kundrick. Positron emission tomography costs less to patients than conventional screening for malignancy in dermatomyositis.  Semin Arthritis Rheu. 02 November 2018.

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    2019-05-16 feather89
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    2018-11-21 Alice yang1118

    学习了,不错的学习材料

    0

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    2018-11-21 Alice yang1118

    学习了,不错的学习材料

    0

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    2018-11-20 Alice yang1118

    学习啦,每天都有进步

    0

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    2018-11-20 zhaojie88
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