JAHA:性侵史与中年颈动脉斑块之间的关系

2021-02-24 MedSci原创 MedSci原创

性侵与更严重的颈动脉粥样硬化水平和更大程度的进展有关。这些关联不能用标准的心血管疾病危险因素来解释。未来的研究工作应该考虑预防性侵是否能降低女性患心血管疾病的风险。

性侵是导致受害者心理不健康的一个危险因素,但它与血管疾病风险之间的关系尚未明确。近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员旨在评估女性性侵史是否与中年时期更高的颈动脉粥样硬化水平和进展相关。

在5年内,研究人员共对169名40至60岁的不吸烟、无心血管疾病的女性进行了两次随访。在每次随访,女性都要完成问卷调查、身体检查、静脉切开术和颈动脉超声检查。研究人员通过多分类logistic和线性回归模型评估了性侵史与颈动脉斑块水平(得分为0、1、≥2)和进展(得分变化)之间的关系,并对年龄、民族、受教育程度、体重指数、血压、血脂、胰岛素抵抗和其他抑郁/创伤后应激症状进行了调整。

28%的受访女性报告有性侵犯史。与无性侵史的女性相比,有性侵史的女性在基线时颈动脉斑块评分≥2的几率高出4倍(相比于无斑块,颈动脉斑块评分≥2的比值比[95%CI]=4.35 [1.48-12.79],P=0.008;颈动脉斑块评分为1的OR [95%CI]=0.49 [0.12-1.97],P=0.32);随访时斑块评分≥2的几率高出3倍(相比于无斑块,斑块评分≥2的OR [95%CI]=3.65 [1.40-9.51],P=0.008;斑块评分为1的OR [95%CI]=1.52 [0.46-4.99],P=0.49)。有性侵史的女性颈动脉斑块评分进展≥2的几率也要高出3倍以上(OR [95%CI]=3.48[1.11-10.93], P=0.033)。抑郁和创伤后症状都与颈动脉斑块无关。

由此可见,性侵与更严重的颈动脉粥样硬化水平和更大程度的进展有关。这些关联不能用标准的心血管疾病危险因素来解释。未来的研究工作应该考虑预防性侵是否能降低女性患心血管疾病的风险。

原始出处:

Rebecca C. Thurston.et al.Sexual Assault and Carotid Plaque Among Midlife Women.J AM HEART ASSOC.2021.https://www.ahajournals.org/doi/10.1161/JAHA.120.017629

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    2021-02-26 T2DM终结者

    心理应激是一辈子的...哎...

    0

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    2021-02-25 zhaohui6731
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    2021-02-24 学医无涯

    性侵心理应激后患无穷!

    0

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