BMJ:高血压、吸烟、肥胖对中青年人的心衰发病影响,甚于高龄老年人

2021-07-26 心血管健康联盟 心血管健康联盟

心力衰竭是65岁以上老年人群住院的重要原因之一,临床上也将其认定为衰老相关的一类疾病。不过,过去十余年里,在青年、中年人群中,心衰发病例数越来越多,有必要对相关危险因素做进一步探明。

心力衰竭是65岁以上老年人群住院的重要原因之一,临床上也将其认定为衰老相关的一类疾病。不过,过去十余年里,在青年、中年人群中,心衰发病例数越来越多,有必要对相关危险因素做进一步探明。

美国麻省总医院学者评估了一般人群心衰危险因素的年龄差异,结果已发表在了四大医学杂志之一的《BMJ》上。

研究人员从弗雷明汉心脏研究 (FHS)、预防肾脏和血管终末期疾病研究(PREVEND)、动脉粥样硬化多种族研究 (MESA)三项大型流行病学队列研究中,共纳入24675例无心衰史参与者。依据年龄,分为青年(<55岁)、中年(55-64岁)、老年(65-74岁)、高龄(>75岁)四组。

图1:各年龄层人群的基线资料和临床数据

研究的中位随访时间长达12.7年,共统计到1381例心衰事件。四组人群(年龄由低到高)的心衰发病率分别为1%、5%、10%、18%,青年组、高龄组的中位心衰发病年龄分别为58岁、89岁。

其中,青年组的射血分数保留型/降低型心衰占比分别为32%、66%,高龄组为43%、41%。

图:2:不同年龄层的各危险因素与心衰事件关联的森林图

同较年长人群相比,吸烟、高血压、糖尿病、既往心梗史,带给较年轻人群的心衰发病风险明显更高:

高血压可使青年组人群的心衰风险增加至原来的3倍,而仅使得高龄人群的心衰风险增加43%;

糖尿病可使青年、高龄人群的心衰风险风别增加至原来的3.86、1.66倍;

吸烟2.58、1.21倍,既往心梗史3.3、1.35倍。

无论有无危险因素,较年轻者发生心衰的绝对风险,均低于较年长者。

图3:不同年龄层发生心衰的各危险因素归因危险度柱状图

此外,除既往房颤史外,其他统计在内的各危险因素上,青年组对比高龄人群(75岁以上)的归因危险度均更高:

男性(21% v 13%),肥胖(21% v 13%),高血压 (35% v 23%),糖尿病(14% v 7%),吸烟(32% v 1%),既往心梗(6% v 1%)。

总的来说,虽然年轻人群的心衰发病率和绝对风险相对更低,但吸烟、高血压等危险因素对其的影响也更大,施以预防性措施调节可控因素,一定程度上可有效延缓或避免心衰的发生。

原始出处:

Jasper Tromp, et al. Age dependent associations of risk factors with heart failure: pooled population based cohort study. BMJ 2021; 372.

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    2022-05-17 zll0625
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    2022-07-11 gaoxiaoe
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  4. [GetPortalCommentsPageByObjectIdResponse(id=1916820, encodeId=30a3191682080, content=<a href='/topic/show?id=f24198994a6' target=_blank style='color:#2F92EE;'>#青年人#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98994, encryptionId=f24198994a6, topicName=青年人)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=284b425, createdName=zll0625, createdTime=Tue May 17 05:46:47 CST 2022, time=2022-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849296, encodeId=24cf184929681, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Mon Jul 11 21:46:47 CST 2022, time=2022-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997653, encodeId=afb0199e653bb, content=<a href='/topic/show?id=2d3b102838bb' target=_blank style='color:#2F92EE;'>#高龄老年#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102838, encryptionId=2d3b102838bb, topicName=高龄老年)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Thu Sep 09 14:46:47 CST 2021, time=2021-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416124, encodeId=01e914161245f, content=<a href='/topic/show?id=99fb1028231b' target=_blank style='color:#2F92EE;'>#高龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102823, encryptionId=99fb1028231b, topicName=高龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=307c3130149, createdName=xlysu, createdTime=Tue Jul 27 23:46:47 CST 2021, time=2021-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596199, encodeId=e236159619918, content=<a href='/topic/show?id=6e342260237' target=_blank style='color:#2F92EE;'>#中青年#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22602, encryptionId=6e342260237, topicName=中青年)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Tue Jul 27 23:46:47 CST 2021, time=2021-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002736, encodeId=5d971002e36a1, content=刚好需要这样的数据做比较, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210508/881c802375f942f0b336bf06cfbddf0f/b0b6c9c62d534bc98724c0a45cdbce98.jpg, createdBy=5fea2491336, createdName=1247c179m39暂无昵称, createdTime=Mon Jul 26 13:53:44 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002678, encodeId=0ed310026e84f, content=多运动,少吸烟, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/2021716/1626423330421_5416545.png, createdBy=4c155541726, createdName=梅斯医学知识点, createdTime=Mon Jul 26 10:14:37 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002688, encodeId=1bec10026885a, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>正好需要这个数据参考一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3da35517808, createdName=ms9000001291633670, createdTime=Mon Jul 26 10:39:31 CST 2021, time=2021-07-26, status=1, ipAttribution=)]
    2021-07-27 xlysu
  5. [GetPortalCommentsPageByObjectIdResponse(id=1916820, encodeId=30a3191682080, content=<a href='/topic/show?id=f24198994a6' target=_blank style='color:#2F92EE;'>#青年人#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98994, encryptionId=f24198994a6, topicName=青年人)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=284b425, createdName=zll0625, createdTime=Tue May 17 05:46:47 CST 2022, time=2022-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849296, encodeId=24cf184929681, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Mon Jul 11 21:46:47 CST 2022, time=2022-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997653, encodeId=afb0199e653bb, content=<a href='/topic/show?id=2d3b102838bb' target=_blank style='color:#2F92EE;'>#高龄老年#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102838, encryptionId=2d3b102838bb, topicName=高龄老年)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Thu Sep 09 14:46:47 CST 2021, time=2021-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416124, encodeId=01e914161245f, content=<a href='/topic/show?id=99fb1028231b' target=_blank style='color:#2F92EE;'>#高龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102823, encryptionId=99fb1028231b, topicName=高龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=307c3130149, createdName=xlysu, createdTime=Tue Jul 27 23:46:47 CST 2021, time=2021-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596199, encodeId=e236159619918, content=<a href='/topic/show?id=6e342260237' target=_blank style='color:#2F92EE;'>#中青年#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22602, encryptionId=6e342260237, topicName=中青年)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Tue Jul 27 23:46:47 CST 2021, time=2021-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002736, encodeId=5d971002e36a1, content=刚好需要这样的数据做比较, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210508/881c802375f942f0b336bf06cfbddf0f/b0b6c9c62d534bc98724c0a45cdbce98.jpg, createdBy=5fea2491336, createdName=1247c179m39暂无昵称, createdTime=Mon Jul 26 13:53:44 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002678, encodeId=0ed310026e84f, content=多运动,少吸烟, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/2021716/1626423330421_5416545.png, createdBy=4c155541726, createdName=梅斯医学知识点, createdTime=Mon Jul 26 10:14:37 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002688, encodeId=1bec10026885a, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>正好需要这个数据参考一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3da35517808, createdName=ms9000001291633670, createdTime=Mon Jul 26 10:39:31 CST 2021, time=2021-07-26, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1916820, encodeId=30a3191682080, content=<a href='/topic/show?id=f24198994a6' target=_blank style='color:#2F92EE;'>#青年人#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98994, encryptionId=f24198994a6, topicName=青年人)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=284b425, createdName=zll0625, createdTime=Tue May 17 05:46:47 CST 2022, time=2022-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849296, encodeId=24cf184929681, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Mon Jul 11 21:46:47 CST 2022, time=2022-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997653, encodeId=afb0199e653bb, content=<a href='/topic/show?id=2d3b102838bb' target=_blank style='color:#2F92EE;'>#高龄老年#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102838, encryptionId=2d3b102838bb, topicName=高龄老年)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Thu Sep 09 14:46:47 CST 2021, time=2021-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416124, encodeId=01e914161245f, content=<a href='/topic/show?id=99fb1028231b' target=_blank style='color:#2F92EE;'>#高龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102823, encryptionId=99fb1028231b, topicName=高龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=307c3130149, createdName=xlysu, createdTime=Tue Jul 27 23:46:47 CST 2021, time=2021-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596199, encodeId=e236159619918, content=<a href='/topic/show?id=6e342260237' target=_blank style='color:#2F92EE;'>#中青年#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22602, encryptionId=6e342260237, topicName=中青年)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Tue Jul 27 23:46:47 CST 2021, time=2021-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002736, encodeId=5d971002e36a1, content=刚好需要这样的数据做比较, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210508/881c802375f942f0b336bf06cfbddf0f/b0b6c9c62d534bc98724c0a45cdbce98.jpg, createdBy=5fea2491336, createdName=1247c179m39暂无昵称, createdTime=Mon Jul 26 13:53:44 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002678, encodeId=0ed310026e84f, content=多运动,少吸烟, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/2021716/1626423330421_5416545.png, createdBy=4c155541726, createdName=梅斯医学知识点, createdTime=Mon Jul 26 10:14:37 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002688, encodeId=1bec10026885a, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>正好需要这个数据参考一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3da35517808, createdName=ms9000001291633670, createdTime=Mon Jul 26 10:39:31 CST 2021, time=2021-07-26, status=1, ipAttribution=)]
    2021-07-26 1247c179m39暂无昵称

    刚好需要这样的数据做比较

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1916820, encodeId=30a3191682080, content=<a href='/topic/show?id=f24198994a6' target=_blank style='color:#2F92EE;'>#青年人#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98994, encryptionId=f24198994a6, topicName=青年人)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=284b425, createdName=zll0625, createdTime=Tue May 17 05:46:47 CST 2022, time=2022-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849296, encodeId=24cf184929681, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Mon Jul 11 21:46:47 CST 2022, time=2022-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997653, encodeId=afb0199e653bb, content=<a href='/topic/show?id=2d3b102838bb' target=_blank style='color:#2F92EE;'>#高龄老年#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102838, encryptionId=2d3b102838bb, topicName=高龄老年)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Thu Sep 09 14:46:47 CST 2021, time=2021-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416124, encodeId=01e914161245f, content=<a href='/topic/show?id=99fb1028231b' target=_blank style='color:#2F92EE;'>#高龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102823, encryptionId=99fb1028231b, topicName=高龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=307c3130149, createdName=xlysu, createdTime=Tue Jul 27 23:46:47 CST 2021, time=2021-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596199, encodeId=e236159619918, content=<a href='/topic/show?id=6e342260237' target=_blank style='color:#2F92EE;'>#中青年#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22602, encryptionId=6e342260237, topicName=中青年)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Tue Jul 27 23:46:47 CST 2021, time=2021-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002736, encodeId=5d971002e36a1, content=刚好需要这样的数据做比较, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210508/881c802375f942f0b336bf06cfbddf0f/b0b6c9c62d534bc98724c0a45cdbce98.jpg, createdBy=5fea2491336, createdName=1247c179m39暂无昵称, createdTime=Mon Jul 26 13:53:44 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002678, encodeId=0ed310026e84f, content=多运动,少吸烟, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/2021716/1626423330421_5416545.png, createdBy=4c155541726, createdName=梅斯医学知识点, createdTime=Mon Jul 26 10:14:37 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002688, encodeId=1bec10026885a, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>正好需要这个数据参考一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3da35517808, createdName=ms9000001291633670, createdTime=Mon Jul 26 10:39:31 CST 2021, time=2021-07-26, status=1, ipAttribution=)]
    2021-07-26 梅斯医学知识点

    多运动,少吸烟

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1916820, encodeId=30a3191682080, content=<a href='/topic/show?id=f24198994a6' target=_blank style='color:#2F92EE;'>#青年人#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98994, encryptionId=f24198994a6, topicName=青年人)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=284b425, createdName=zll0625, createdTime=Tue May 17 05:46:47 CST 2022, time=2022-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849296, encodeId=24cf184929681, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Mon Jul 11 21:46:47 CST 2022, time=2022-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997653, encodeId=afb0199e653bb, content=<a href='/topic/show?id=2d3b102838bb' target=_blank style='color:#2F92EE;'>#高龄老年#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102838, encryptionId=2d3b102838bb, topicName=高龄老年)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Thu Sep 09 14:46:47 CST 2021, time=2021-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416124, encodeId=01e914161245f, content=<a href='/topic/show?id=99fb1028231b' target=_blank style='color:#2F92EE;'>#高龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102823, encryptionId=99fb1028231b, topicName=高龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=307c3130149, createdName=xlysu, createdTime=Tue Jul 27 23:46:47 CST 2021, time=2021-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596199, encodeId=e236159619918, content=<a href='/topic/show?id=6e342260237' target=_blank style='color:#2F92EE;'>#中青年#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22602, encryptionId=6e342260237, topicName=中青年)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Tue Jul 27 23:46:47 CST 2021, time=2021-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002736, encodeId=5d971002e36a1, content=刚好需要这样的数据做比较, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210508/881c802375f942f0b336bf06cfbddf0f/b0b6c9c62d534bc98724c0a45cdbce98.jpg, createdBy=5fea2491336, createdName=1247c179m39暂无昵称, createdTime=Mon Jul 26 13:53:44 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002678, encodeId=0ed310026e84f, content=多运动,少吸烟, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/2021716/1626423330421_5416545.png, createdBy=4c155541726, createdName=梅斯医学知识点, createdTime=Mon Jul 26 10:14:37 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002688, encodeId=1bec10026885a, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>正好需要这个数据参考一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3da35517808, createdName=ms9000001291633670, createdTime=Mon Jul 26 10:39:31 CST 2021, time=2021-07-26, status=1, ipAttribution=)]
    2021-07-26 ms9000001291633670

    #学习#正好需要这个数据参考一下

    0

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