FDA的顾问们对GW公司的Epidiolex的批准表示支持

2018-04-21 MedSci MedSci原创

正如预期的那样,FDA顾问小组支持GW Pharmaceuticals / Greenwich Bioscience的Epidiolex批准用于治疗与Lennox-Gastaut综合征和Dravet综合征有关的癫痫发作。这一药物获得了周边和中枢神经系统药物咨询委员会一致支持,也使其向市场批准迈出了重要一步,用于2岁及以上的患者。如果批准,Epidiolex(大麻二醇)将是第一个提纯的、基于植物的C


正如预期的那样,FDA顾问小组支持GW Pharmaceuticals / Greenwich Bioscience的Epidiolex批准用于治疗与Lennox-Gastaut综合征和Dravet综合征有关的癫痫发作。

这一药物获得了周边和中枢神经系统药物咨询委员会一致支持,也使其向市场批准迈出了重要一步,用于2岁及以上的患者。

如果批准,Epidiolex(大麻二醇)将是第一个提纯的、基于植物的CBD药物,它是一种大麻素,与大麻相关度不高,并且是第一个新的抗癫痫药物(AEDs)。

LGS和Dravet综合征是儿童期发作性癫痫的破坏性形式,具有高发病率和死亡率,并对家庭和护理人员造成重大负担。超过90%的LGS或Dravet综合征患者每天有多次癫痫发作,这使他们处于跌倒和受伤的危险之中。

临床试验表明,任何一种情况服用Epidiolex的患者每月癫痫发作率均显着降低,而该药物通常具有良好的耐受性,大多数不良事件报告为轻度或中度。

"这些研究结果表明,这种大麻二酚药物制剂为一些可能对某些患者有效的新治疗方案提供希望,"马萨诸塞州总医院儿科癫痫主任,哈佛医学院神经病学教授Elizabeth Thiele评论道。 他也是GW和格林威治研究LGS患者的主要研究者之一。

委员会的决定不具有约束力,但FDA通常倾向于遵循它的建议。最终决定将于6月27日做出。


此文系梅斯医学(MedSci)原创整理编译,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=308992, encodeId=f7f230899269, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/2EVCwc9WmQS6ec99H2TX8ejmR40xYjwrIcrqjAnibV36aicL1sLxc21rhpZnqTOxk33HP44iayEwo6qYXqgZvdRtA/132, createdBy=d0d01573846, createdName=329523732, createdTime=Wed Apr 25 00:48:43 CST 2018, time=2018-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581571, encodeId=f5fa15815e1ca, content=<a href='/topic/show?id=938b68e713' target=_blank style='color:#2F92EE;'>#Epidiolex#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6877, encryptionId=938b68e713, topicName=Epidiolex)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9acc16815920, createdName=ms3415360956839622, createdTime=Mon Apr 23 13:34:00 CST 2018, time=2018-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308138, encodeId=8c09308138fc, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sun Apr 22 07:35:01 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308042, encodeId=04cb30804243, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Sun Apr 22 00:24:58 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308015, encodeId=15e43080159d, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sat Apr 21 23:56:17 CST 2018, time=2018-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308004, encodeId=47153080048d, content=如果批准.Epidiolex(大麻二醇)将是第一个提纯的.基于植物的CBD药物.它是一种大麻素.与大麻相关度不高.并且是第一个新的抗癫痫药物(AEDs)., beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Apr 21 23:05:30 CST 2018, time=2018-04-21, status=1, ipAttribution=)]
    2018-04-25 329523732

    不错

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=308992, encodeId=f7f230899269, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/2EVCwc9WmQS6ec99H2TX8ejmR40xYjwrIcrqjAnibV36aicL1sLxc21rhpZnqTOxk33HP44iayEwo6qYXqgZvdRtA/132, createdBy=d0d01573846, createdName=329523732, createdTime=Wed Apr 25 00:48:43 CST 2018, time=2018-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581571, encodeId=f5fa15815e1ca, content=<a href='/topic/show?id=938b68e713' target=_blank style='color:#2F92EE;'>#Epidiolex#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6877, encryptionId=938b68e713, topicName=Epidiolex)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9acc16815920, createdName=ms3415360956839622, createdTime=Mon Apr 23 13:34:00 CST 2018, time=2018-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308138, encodeId=8c09308138fc, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sun Apr 22 07:35:01 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308042, encodeId=04cb30804243, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Sun Apr 22 00:24:58 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308015, encodeId=15e43080159d, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sat Apr 21 23:56:17 CST 2018, time=2018-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308004, encodeId=47153080048d, content=如果批准.Epidiolex(大麻二醇)将是第一个提纯的.基于植物的CBD药物.它是一种大麻素.与大麻相关度不高.并且是第一个新的抗癫痫药物(AEDs)., beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Apr 21 23:05:30 CST 2018, time=2018-04-21, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=308992, encodeId=f7f230899269, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/2EVCwc9WmQS6ec99H2TX8ejmR40xYjwrIcrqjAnibV36aicL1sLxc21rhpZnqTOxk33HP44iayEwo6qYXqgZvdRtA/132, createdBy=d0d01573846, createdName=329523732, createdTime=Wed Apr 25 00:48:43 CST 2018, time=2018-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581571, encodeId=f5fa15815e1ca, content=<a href='/topic/show?id=938b68e713' target=_blank style='color:#2F92EE;'>#Epidiolex#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6877, encryptionId=938b68e713, topicName=Epidiolex)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9acc16815920, createdName=ms3415360956839622, createdTime=Mon Apr 23 13:34:00 CST 2018, time=2018-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308138, encodeId=8c09308138fc, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sun Apr 22 07:35:01 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308042, encodeId=04cb30804243, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Sun Apr 22 00:24:58 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308015, encodeId=15e43080159d, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sat Apr 21 23:56:17 CST 2018, time=2018-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308004, encodeId=47153080048d, content=如果批准.Epidiolex(大麻二醇)将是第一个提纯的.基于植物的CBD药物.它是一种大麻素.与大麻相关度不高.并且是第一个新的抗癫痫药物(AEDs)., beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Apr 21 23:05:30 CST 2018, time=2018-04-21, status=1, ipAttribution=)]
    2018-04-22 大爰

    学习了谢谢分享!!

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=308992, encodeId=f7f230899269, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/2EVCwc9WmQS6ec99H2TX8ejmR40xYjwrIcrqjAnibV36aicL1sLxc21rhpZnqTOxk33HP44iayEwo6qYXqgZvdRtA/132, createdBy=d0d01573846, createdName=329523732, createdTime=Wed Apr 25 00:48:43 CST 2018, time=2018-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581571, encodeId=f5fa15815e1ca, content=<a href='/topic/show?id=938b68e713' target=_blank style='color:#2F92EE;'>#Epidiolex#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6877, encryptionId=938b68e713, topicName=Epidiolex)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9acc16815920, createdName=ms3415360956839622, createdTime=Mon Apr 23 13:34:00 CST 2018, time=2018-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308138, encodeId=8c09308138fc, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sun Apr 22 07:35:01 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308042, encodeId=04cb30804243, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Sun Apr 22 00:24:58 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308015, encodeId=15e43080159d, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sat Apr 21 23:56:17 CST 2018, time=2018-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308004, encodeId=47153080048d, content=如果批准.Epidiolex(大麻二醇)将是第一个提纯的.基于植物的CBD药物.它是一种大麻素.与大麻相关度不高.并且是第一个新的抗癫痫药物(AEDs)., beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Apr 21 23:05:30 CST 2018, time=2018-04-21, status=1, ipAttribution=)]
    2018-04-22 sunfeifeiyang

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=308992, encodeId=f7f230899269, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/2EVCwc9WmQS6ec99H2TX8ejmR40xYjwrIcrqjAnibV36aicL1sLxc21rhpZnqTOxk33HP44iayEwo6qYXqgZvdRtA/132, createdBy=d0d01573846, createdName=329523732, createdTime=Wed Apr 25 00:48:43 CST 2018, time=2018-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581571, encodeId=f5fa15815e1ca, content=<a href='/topic/show?id=938b68e713' target=_blank style='color:#2F92EE;'>#Epidiolex#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6877, encryptionId=938b68e713, topicName=Epidiolex)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9acc16815920, createdName=ms3415360956839622, createdTime=Mon Apr 23 13:34:00 CST 2018, time=2018-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308138, encodeId=8c09308138fc, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sun Apr 22 07:35:01 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308042, encodeId=04cb30804243, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Sun Apr 22 00:24:58 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308015, encodeId=15e43080159d, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sat Apr 21 23:56:17 CST 2018, time=2018-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308004, encodeId=47153080048d, content=如果批准.Epidiolex(大麻二醇)将是第一个提纯的.基于植物的CBD药物.它是一种大麻素.与大麻相关度不高.并且是第一个新的抗癫痫药物(AEDs)., beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Apr 21 23:05:30 CST 2018, time=2018-04-21, status=1, ipAttribution=)]
    2018-04-21 1e0f8808m18(暂无匿称)

    学习了.谢谢分享.

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=308992, encodeId=f7f230899269, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/2EVCwc9WmQS6ec99H2TX8ejmR40xYjwrIcrqjAnibV36aicL1sLxc21rhpZnqTOxk33HP44iayEwo6qYXqgZvdRtA/132, createdBy=d0d01573846, createdName=329523732, createdTime=Wed Apr 25 00:48:43 CST 2018, time=2018-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581571, encodeId=f5fa15815e1ca, content=<a href='/topic/show?id=938b68e713' target=_blank style='color:#2F92EE;'>#Epidiolex#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6877, encryptionId=938b68e713, topicName=Epidiolex)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9acc16815920, createdName=ms3415360956839622, createdTime=Mon Apr 23 13:34:00 CST 2018, time=2018-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308138, encodeId=8c09308138fc, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sun Apr 22 07:35:01 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308042, encodeId=04cb30804243, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Sun Apr 22 00:24:58 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308015, encodeId=15e43080159d, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sat Apr 21 23:56:17 CST 2018, time=2018-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308004, encodeId=47153080048d, content=如果批准.Epidiolex(大麻二醇)将是第一个提纯的.基于植物的CBD药物.它是一种大麻素.与大麻相关度不高.并且是第一个新的抗癫痫药物(AEDs)., beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Apr 21 23:05:30 CST 2018, time=2018-04-21, status=1, ipAttribution=)]
    2018-04-21 有备才能无患

    如果批准.Epidiolex(大麻二醇)将是第一个提纯的.基于植物的CBD药物.它是一种大麻素.与大麻相关度不高.并且是第一个新的抗癫痫药物(AEDs).

    0

相关资讯

lancet发布的数据显示了GW公司Epidiolex的潜力

《柳叶刀》杂志发表了一项三期研究的数据,该研究支持使用GW制药/格林尼治生物科学的Epidiolex来治疗Lennox-Gastaut综合征(LGS)。LGS是一种罕见的终身癫痫,与高死亡率和严重的发育迟缓有关。患者遭受多种癫痫发作,包括小发作癫痫,可能导致跌倒和其他伤害。根据GW的数据,来自lancet发表的研究结果"代表了大麻素药物对这种严重耐药的唯一有效的临床评估。"在试验中,有171名LG

FDA授予Epidiolex(大麻二酚)治疗结节性硬化症(TSC)的孤儿药地位

美国食品和药物管理局(FDA)近日授予GW制药公司的药物Epidiolex(大麻二酚,CBD)治疗罕见遗传性结节性硬化症(TSC)的孤儿药地位。 TSC可在许多不同的器官中导致非恶性肿瘤,其中大脑和皮肤是最常见的受影响组织。据估计,在全球范围内大约有100万例TSC患者,美国约有5万例。TSC最常见的症状是癫痫,发生于80%-90%的患者中,同时也是TSC患者发病和死亡的重要原因。 本月早

大麻提取物治疗难治性儿童癫痫显奇效

GW制药公司近日公布了药物Epidiolex(大麻二醇,CBD)治疗Lennox-Gastaut综合征(LGS)的首个随机、双盲、安慰剂对照III期临床研究的积极数据。LGS是一种罕见的、严重的、难治性儿童期发作癫痫。该项研究中的患者已经接受平均9种抗癫痫药物的治疗。研究中,将安慰剂或Epidiolex添加至患者当前的治疗方案。数据显示,当作为一种辅助药物用药时,在整个14周治疗期间,与安慰剂相比

GW制药领军药Epidiolex三期临床成功,股价立马翻倍!

伦敦GW制药公司发布公告称,其以大麻提取物为活性成分的epilepsy治疗罕见病Dravet综合征三期临床表现良好。该三期临床结果将大大提高通过FDA批准上市几率。这则重大利好使其股价暴涨一倍多,从38美元一度飙到91美元,让不少投资者乐开了花。 Epidiolex 是一种口服的、高纯度 CBD 提取物液体制剂,CBD 是一种来自大麻植物的非精神类成分,不会引起幻觉。GW坚信该药能减少一

大麻提取物(Epidiolex)治疗难治性儿童癫痫再显奇效

英国GW制药公司近日公布了大麻提取物Epidiolex(cannabidiol,大麻二醇,CBD)治疗Lennox-Gastaut综合征(LGS)的第二个随机、双盲、安慰剂对照III期临床研究的积极数据。LGS是一种罕见的、严重的、难治性儿童期发作癫痫。该项研究中的患者之前已尝试过平均7种抗癫痫药物,目前正在接受平均3种药物治疗。 研究中,将安慰剂或Epidiolex添加至患者当前的治疗方案