JAMA Neurol:出生队列分析中痴呆发病率的变化趋势

2017-09-09 zhangfan MedSci原创

研究证实,痴呆的发病率在人口样本中呈现出下降的趋势,但由于人口老龄化程度的加重,世界范围内痴呆症负担仍十分沉重

痴呆发病率的变化趋势对疾病的规划和预防有重要影响。为了更好地了解发病趋势随着时间变化,需要分离的年龄和队列效应。近日研究人员考察了70岁以上老年人痴呆发病率的变化趋势。

这项出生队列分析考察了1993-2015年间所有参与者的痴呆发病率,共1348人参与者研究。参与者年龄在70岁以上,基线无痴呆症状,至少有一年随访。采用泊松回归考察痴呆发病率与年龄,性别,文化程度,种族和出生时间的关系。

研究发现,痴呆发病率呈现出下降趋势:1920年前出生人群的痴呆发病率为每100患者年5.09,1920-1924年间人群的发病率下降至3.11,1925-1929年间下降至1.73,在1929年之后出生人群的患病风险降低至0.23。变化点分析发现,1929年7月以后出生人群,痴呆发病率显著下降,其风险仅为之前出生人群的0.13。在连续出生队列中,卒中心肌梗死的患病率下降,糖尿病患病率升高,但心血管合并症下降不能解释痴呆发病率下降的原因。

研究证实,痴呆的发病率在人口样本中呈现出下降的趋势,但由于人口老龄化程度的加重,世界范围内痴呆症负担仍十分沉重。

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createdName=Julie W, createdTime=Sat Sep 09 14:35:13 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242190, encodeId=fcf22421907c, content=痴呆发病率的变化趋势对疾病的规划和预防有重要影响.为了更好地了解发病趋势随着时间变化.需要分离的年龄和队列效应.近日研究人员考察了70岁以上老年人痴呆发病率的变化趋势., beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:34:43 CST 2017, time=2017-09-09, status=1, ipAttribution=)]
    2017-09-29 yinhl1978
  3. 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  4. 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createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Mon Sep 11 08:35:58 CST 2017, time=2017-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242436, encodeId=6c542424366c, content=区域差别很大的, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCclExeQ6LOGMD4dTsia4Ty4HtZCxRmG5vO5XIKfKX3a3vusfhHSej4Iib517vmhFW7RQgh7bpDp1yw/0, createdBy=50951609779, createdName=baihao215, createdTime=Sun Sep 10 07:38:27 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242428, encodeId=454724242862, content=现在寿命长了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sun Sep 10 07:33:00 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242217, encodeId=fa8524221e78, content=痴呆的发病率在人口样本中呈现出下降的趋势.但由于人口老龄化程度的加重.世界范围内痴呆症负担仍十分沉重., beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Sep 09 16:23:07 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242192, encodeId=a246242192d4, content=研究证实.痴呆的发病率在人口样本中呈现出下降的趋势.但由于人口老龄化程度的加重.世界范围内痴呆症负担仍十分沉重., beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:35:23 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242191, encodeId=8559242191bb, content=研究发现.痴呆发病率呈现出下降趋势:1920年前出生人群的痴呆发病率为每100患者年5.09.1920-1924年间人群的发病率下降至3.11.1925-1929年间下降至1.73.在1929年之后出生人群的患病风险降低至0.23.变化点分析发现.1929年7月以后出生人群.痴呆发病率显著下降.其风险仅为之前出生人群的0.13.在连续出生队列中.卒中和心肌梗死的患病率下降.糖尿病患病率升高.但心血管合并症下降不能解释痴呆发病率下降的原因., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:35:13 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242190, encodeId=fcf22421907c, content=痴呆发病率的变化趋势对疾病的规划和预防有重要影响.为了更好地了解发病趋势随着时间变化.需要分离的年龄和队列效应.近日研究人员考察了70岁以上老年人痴呆发病率的变化趋势., beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:34:43 CST 2017, time=2017-09-09, status=1, ipAttribution=)]
    2017-09-11 一个字-牛

    学习了谢谢分享

    0

  5. 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createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Mon Sep 11 08:35:58 CST 2017, time=2017-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242436, encodeId=6c542424366c, content=区域差别很大的, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCclExeQ6LOGMD4dTsia4Ty4HtZCxRmG5vO5XIKfKX3a3vusfhHSej4Iib517vmhFW7RQgh7bpDp1yw/0, createdBy=50951609779, createdName=baihao215, createdTime=Sun Sep 10 07:38:27 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242428, encodeId=454724242862, content=现在寿命长了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:35:23 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242191, encodeId=8559242191bb, content=研究发现.痴呆发病率呈现出下降趋势:1920年前出生人群的痴呆发病率为每100患者年5.09.1920-1924年间人群的发病率下降至3.11.1925-1929年间下降至1.73.在1929年之后出生人群的患病风险降低至0.23.变化点分析发现.1929年7月以后出生人群.痴呆发病率显著下降.其风险仅为之前出生人群的0.13.在连续出生队列中.卒中和心肌梗死的患病率下降.糖尿病患病率升高.但心血管合并症下降不能解释痴呆发病率下降的原因., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:35:13 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242190, encodeId=fcf22421907c, content=痴呆发病率的变化趋势对疾病的规划和预防有重要影响.为了更好地了解发病趋势随着时间变化.需要分离的年龄和队列效应.近日研究人员考察了70岁以上老年人痴呆发病率的变化趋势., beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:34:43 CST 2017, time=2017-09-09, status=1, ipAttribution=)]
    2017-09-10 baihao215

    区域差别很大的

    0

  6. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:35:23 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242191, encodeId=8559242191bb, content=研究发现.痴呆发病率呈现出下降趋势:1920年前出生人群的痴呆发病率为每100患者年5.09.1920-1924年间人群的发病率下降至3.11.1925-1929年间下降至1.73.在1929年之后出生人群的患病风险降低至0.23.变化点分析发现.1929年7月以后出生人群.痴呆发病率显著下降.其风险仅为之前出生人群的0.13.在连续出生队列中.卒中和心肌梗死的患病率下降.糖尿病患病率升高.但心血管合并症下降不能解释痴呆发病率下降的原因., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:35:13 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242190, encodeId=fcf22421907c, content=痴呆发病率的变化趋势对疾病的规划和预防有重要影响.为了更好地了解发病趋势随着时间变化.需要分离的年龄和队列效应.近日研究人员考察了70岁以上老年人痴呆发病率的变化趋势., beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:34:43 CST 2017, time=2017-09-09, status=1, ipAttribution=)]
    2017-09-10 meiliwuxian

    现在寿命长了

    0

  7. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:35:23 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242191, encodeId=8559242191bb, content=研究发现.痴呆发病率呈现出下降趋势:1920年前出生人群的痴呆发病率为每100患者年5.09.1920-1924年间人群的发病率下降至3.11.1925-1929年间下降至1.73.在1929年之后出生人群的患病风险降低至0.23.变化点分析发现.1929年7月以后出生人群.痴呆发病率显著下降.其风险仅为之前出生人群的0.13.在连续出生队列中.卒中和心肌梗死的患病率下降.糖尿病患病率升高.但心血管合并症下降不能解释痴呆发病率下降的原因., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:35:13 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242190, encodeId=fcf22421907c, content=痴呆发病率的变化趋势对疾病的规划和预防有重要影响.为了更好地了解发病趋势随着时间变化.需要分离的年龄和队列效应.近日研究人员考察了70岁以上老年人痴呆发病率的变化趋势., beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:34:43 CST 2017, time=2017-09-09, status=1, ipAttribution=)]
    2017-09-09 有备才能无患

    痴呆的发病率在人口样本中呈现出下降的趋势.但由于人口老龄化程度的加重.世界范围内痴呆症负担仍十分沉重.

    0

  8. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:35:23 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242191, encodeId=8559242191bb, content=研究发现.痴呆发病率呈现出下降趋势:1920年前出生人群的痴呆发病率为每100患者年5.09.1920-1924年间人群的发病率下降至3.11.1925-1929年间下降至1.73.在1929年之后出生人群的患病风险降低至0.23.变化点分析发现.1929年7月以后出生人群.痴呆发病率显著下降.其风险仅为之前出生人群的0.13.在连续出生队列中.卒中和心肌梗死的患病率下降.糖尿病患病率升高.但心血管合并症下降不能解释痴呆发病率下降的原因., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:35:13 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242190, encodeId=fcf22421907c, content=痴呆发病率的变化趋势对疾病的规划和预防有重要影响.为了更好地了解发病趋势随着时间变化.需要分离的年龄和队列效应.近日研究人员考察了70岁以上老年人痴呆发病率的变化趋势., beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:34:43 CST 2017, time=2017-09-09, status=1, ipAttribution=)]
    2017-09-09 Julie W

    研究证实.痴呆的发病率在人口样本中呈现出下降的趋势.但由于人口老龄化程度的加重.世界范围内痴呆症负担仍十分沉重.

    0

  9. 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createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Mon Sep 11 08:35:58 CST 2017, time=2017-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242436, encodeId=6c542424366c, content=区域差别很大的, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCclExeQ6LOGMD4dTsia4Ty4HtZCxRmG5vO5XIKfKX3a3vusfhHSej4Iib517vmhFW7RQgh7bpDp1yw/0, createdBy=50951609779, createdName=baihao215, createdTime=Sun Sep 10 07:38:27 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242428, encodeId=454724242862, content=现在寿命长了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sun Sep 10 07:33:00 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242217, encodeId=fa8524221e78, content=痴呆的发病率在人口样本中呈现出下降的趋势.但由于人口老龄化程度的加重.世界范围内痴呆症负担仍十分沉重., beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Sep 09 16:23:07 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242192, encodeId=a246242192d4, content=研究证实.痴呆的发病率在人口样本中呈现出下降的趋势.但由于人口老龄化程度的加重.世界范围内痴呆症负担仍十分沉重., beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:35:23 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242191, encodeId=8559242191bb, content=研究发现.痴呆发病率呈现出下降趋势:1920年前出生人群的痴呆发病率为每100患者年5.09.1920-1924年间人群的发病率下降至3.11.1925-1929年间下降至1.73.在1929年之后出生人群的患病风险降低至0.23.变化点分析发现.1929年7月以后出生人群.痴呆发病率显著下降.其风险仅为之前出生人群的0.13.在连续出生队列中.卒中和心肌梗死的患病率下降.糖尿病患病率升高.但心血管合并症下降不能解释痴呆发病率下降的原因., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:35:13 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242190, encodeId=fcf22421907c, content=痴呆发病率的变化趋势对疾病的规划和预防有重要影响.为了更好地了解发病趋势随着时间变化.需要分离的年龄和队列效应.近日研究人员考察了70岁以上老年人痴呆发病率的变化趋势., beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:34:43 CST 2017, time=2017-09-09, status=1, ipAttribution=)]
    2017-09-09 Julie W

    研究发现.痴呆发病率呈现出下降趋势:1920年前出生人群的痴呆发病率为每100患者年5.09.1920-1924年间人群的发病率下降至3.11.1925-1929年间下降至1.73.在1929年之后出生人群的患病风险降低至0.23.变化点分析发现.1929年7月以后出生人群.痴呆发病率显著下降.其风险仅为之前出生人群的0.13.在连续出生队列中.卒中和心肌梗死的患病率下降.糖尿病患病率升高.但心血管合并症下降不能解释痴呆发病率下降的原因.

    0

  10. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:35:23 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242191, encodeId=8559242191bb, content=研究发现.痴呆发病率呈现出下降趋势:1920年前出生人群的痴呆发病率为每100患者年5.09.1920-1924年间人群的发病率下降至3.11.1925-1929年间下降至1.73.在1929年之后出生人群的患病风险降低至0.23.变化点分析发现.1929年7月以后出生人群.痴呆发病率显著下降.其风险仅为之前出生人群的0.13.在连续出生队列中.卒中和心肌梗死的患病率下降.糖尿病患病率升高.但心血管合并症下降不能解释痴呆发病率下降的原因., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:35:13 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242190, encodeId=fcf22421907c, content=痴呆发病率的变化趋势对疾病的规划和预防有重要影响.为了更好地了解发病趋势随着时间变化.需要分离的年龄和队列效应.近日研究人员考察了70岁以上老年人痴呆发病率的变化趋势., beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Sat Sep 09 14:34:43 CST 2017, time=2017-09-09, status=1, ipAttribution=)]
    2017-09-09 Julie W

    痴呆发病率的变化趋势对疾病的规划和预防有重要影响.为了更好地了解发病趋势随着时间变化.需要分离的年龄和队列效应.近日研究人员考察了70岁以上老年人痴呆发病率的变化趋势.

    0

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