Lancet Psychiatry:超1/3新冠患者脑部出现问题

2021-04-10 “科技导报”公众号 “科技导报”公众号

美东时间4月6日,柳叶刀子刊《柳叶刀-精神病学》(The Lancet Psychiatry)最新发表了一项迄今为止规模最大的研究,来自英国牛津大学和美国的研究人员在研究了超过23.6万名新冠患者健康

美东时间4月6日,柳叶刀子刊《柳叶刀-精神病学》(The Lancet Psychiatry)最新发表了一项迄今为止规模最大的研究,来自英国牛津大学和美国的研究人员在研究了超过23.6万名新冠患者健康数据后发现:

有超过三分之一的新冠治愈者脑部出现问题,在感染半年内被诊断出患有神经或精神疾病。

这项回顾性研究由美国国立卫生研究院(NIHR)牛津健康生物医学研究中心资助,分析了美国236379名新冠患者(10岁以上,在2020年1月20日及之后感染,2020年12月13日仍然健在)的电子健康记录,分析了14种神经系统和精神疾病的诊断情况。

研究人员发现,有高达33.62%的新冠患者在治愈后六个月内被诊断出患有神经或心理疾病。其中12.84%的人是首次得到神经或精神疾病诊断。

其中,17%的患者诊断为焦虑,还有14%的患者身患情绪障碍。在重症患者中,神经系统疾病也不罕见,近7%出现中风(每50名新冠患者中就有一人患有缺血性中风),近2%被诊断出痴呆症。

研究人员还称,如果这项统计包含了住院病人,那么脑部出现问题的病人比例将上升到39%。

此外,研究团队还对比了同时期105579名被诊断为流感的患者和236038名被诊断为任何呼吸道感染(包括流感)的患者数据。

考虑到年龄、性别、族裔和基础疾病等基本健康特征后,新冠感染者诊断出神经和精神疾病的风险,比流感患者高44%,比呼吸道感染患者高16%。

这意味着,与其他流感和呼吸道疾病相比,新冠感染确实会带来更高的神经系统疾病和精神疾病风险。

研究团队也承认研究有所局限,比如,电子病历的完整性和准确性尚不清楚;其次,很多轻症患者或者无症状感染者可能没有前往医院就诊,因此缺乏相关数据,而研究所纳入的感染者可能整体病情比一般人群要严重;另外,神经和精神疾病的严重程度和病程也缺乏深入信息。

“这是从大量患者中收集的真实世界数据,证实了感染新冠后精神疾病诊断率高,还会引发影响神经系统的严重疾病(例如中风和痴呆症)。” 研究通讯作者,英国牛津大学(University of Oxford) Paul Harrison教授表示,“尽管大多数疾病的个体风险很小,但是考虑疫情规模之大,以及很多疾病的慢性、长期影响,因此这些风险在全人群层面的影响是巨大的。”

原始出处:

Maxime Taquet, et al. 6-month neurological and psychiatric outcomes in 236?379 survivors of COVID-19: a retrospective cohort study using electronic health records. Lancet Psychiatry, 2021. DOI:https://doi.org/10.1016/S2215-0366(21)00084-5.

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    2021-09-07 howi
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    2021-04-10 公卫新人

    新冠肺炎,疫情何时才能消失

    0

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    2021-04-10 goodbing

    顶刊就是不一样,质量很高,内容精彩!学到很多

    0

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