JACC:左室质量回归对经导管主动脉瓣置换术预后的影响

2020-05-19 MedSci原创 MedSci原创

早期左室质量指数(LVMi)回归越大,经导管主动脉瓣置换术(TAVR)后1年住院率越低。但LVMi回归与TAVR术后远期的预后相关性尚不清楚。本研究的目的旨在评估LVMi回归与患者术后1-5年临床预后

早期左室质量指数(LVMi)回归越大,经导管主动脉瓣置换术(TAVR)后1年住院率越低。但LVMi回归与TAVR术后远期的预后相关性尚不清楚。本研究的目的旨在评估LVMi回归与患者术后1-5年临床预后的相关性。

本研究纳入分析了PARTNER临床试验中的1434名中高风险接受TAVR治疗的患者,基线水平的LVMi为146g/m2,1年后降至126g/m2。1年后LVMi回归越大,全因死亡率越低(p = 0.004)。另外,术后1年后有39%患者出现有严重的左室肥厚,且与全因死亡率的增加呈相关性(p = 0.003)。心血管死亡率和再住院率也有相似的关联性。

研究结果显示,在接受TAVR手术治疗伴中重度左室肥厚的患者中,术后1年左室质量指数回归越大,患者术后5年的死亡率和住院率越低。

原始出处:

Katherine H et al.Regression of Left Ventricular Mass After Transcatheter Aortic Valve Replacement.JACC.May.

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    2021-01-19 hbwxf
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    2021-01-28 yxch48
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  5. 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  6. 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  8. 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    2020-05-21 lsj631
  9. 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