JACC:吸烟对接受介入治疗后ST段抬高型心梗患者预后的影响

2020-04-20 MedSci原创 MedSci原创

抽烟是已知的ST段抬高型心梗(STEMI)的危险因素,然而,一旦STEMI发生,抽烟可能与短期的预后改善呈相关性。本研究的目的是评估STEMI后,吸烟与梗死面积、微血管阻塞(MVO)和不良结局之间的关

抽烟是已知的ST段抬高型心梗(STEMI)的危险因素,然而,一旦STEMI发生,抽烟可能与短期的预后改善呈相关性。本研究的目的是评估STEMI后,吸烟与梗死面积、微血管阻塞(MVO)和不良结局之间的关系。

本研究纳入分析了来自10个随机临床试验中的2564名接受经皮冠脉介入治疗的STEMI患者,其中1093名(42.6%)患者最近有过抽烟。吸烟者的年龄年轻10岁且并发症更少。梗死面积在抽烟者和非抽烟者中无明显差异,MVO的程度也无明显差异。吸烟者的一年全因死亡率和心衰住院率更低,但是再梗死率无明显差异。在经年龄和其它危险因素调整分析后发现,抽烟者的心衰住院率和再梗死率更高,但1年死亡风险无明显差异。

研究结果显示,对于接受介入治疗的ST段抬高型心梗患者,近期的吸烟与梗死面积和MVO无相关性,但与更差的预后相关。

原始出处:

Björn R et al.Effect of Smoking on Outcomes of Primary PCI in Patients With STEMI.JACC.2020 Apr.

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    2021-03-10 hbwxf
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    2020-04-22 hyf035

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