Diabetes Care:急性高血糖对1型糖尿病青少年空间工作记忆能力的影响

2020-06-01 MedSci原创 MedSci原创

急性高血糖对T1D青少年的sWM能力会产生负面影响,这与受试者的日常功能和学习成绩有关。

近日,糖尿病领域权威杂志Diabetes Care上发表了一篇研究文章,这项研究旨在调查急性高血糖对1型糖尿病(T1D)青少年脑功能的影响。

20名T1D参与者(年龄为14.64±1.78岁)和20名年龄相匹配的健康对照受试者(年龄为14.40±2.82岁)进行了两次功能性MRI检查。T1D参与者在正常血糖下进行第一次检查,在高血糖钳制下(20 mmol/L[360 mg/dL])进行第二次检查。

研究人员观察到T1D受试者急性高血糖期间空间工作记忆(sWM)能力较低,并且在sWM任务的不同阶段中,感兴趣的脑区激活程度存在显著差异(P=0.014)。

由此可见,急性高血糖对T1D青少年的sWM能力会产生负面影响,这与受试者的日常功能和学习成绩有关。

原始出处:

Jasna Šuput Omladič,et al.Acute Hyperglycemia and Spatial Working Memory in Adolescents With Type 1 Diabetes.Diabetes Care.2020.https://doi.org/10.2337/dc20-0171

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    2020-06-03 hbwxf
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    2020-06-01 misszhang

    谢谢MedSci提供最新的资讯

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