JACC:新冠肺炎大流行对ST段抬高型心肌梗死诊疗和预后的影响

2021-04-26 MedSci原创 MedSci原创

近日,印度疫情失控、医疗系统奔溃、氧气缺乏、当街焚尸等宛若“人间炼狱”般的现实提醒着我们,新冠疫情仍尚未结束。

近日,印度疫情失控、医疗系统奔溃、氧气缺乏、当街焚尸等宛若“人间炼狱”般的现实提醒着我们,新冠疫情仍尚未结束。

新冠肺炎除了直接导致死亡之外,其大流行还影响了其他疾病的诊疗。让我们一起来看看新冠肺炎大流行对ST段抬高型心肌梗死(STEMI)诊疗各方面,包括及时接受直接经皮冠状动脉介入治疗(PPCI),的影响吧~

最新发表在“J Am Coll Cardiol上的“Initial Findings From the North American COVID-19 Myocardial Infarction Registry”研究,描述了感染新冠肺炎的STEMI患者的人口学特征、管理策略和临床预后。

研究人员根据3个心脏病学会的指导,建立了一个前瞻性的、持续的观察性注册,纳入了确诊为COVID+感染者(第1组)或疑似新冠肺炎感染者(PUI,第2组)的STEMI患者。还纳入了年龄和性别相匹配的在COVID时代(2015-2019年)前接受治疗的STEMI患者(第3组),作为对照组,以比较治疗策略和临床预后。主要结果包括院内死亡、卒中、再发心肌梗死或重复的非计划的血运重建的综合结局。

截止2020年12月6日,共有1185名患者被纳入NACMI登记(230名COVID+患者、495名PUI患者和460名对照患者)。

各组患者预后

COVID+患者更有可能是少数族裔(西班牙裔 23%、黑人 24%),糖尿病患病率更高(46%)(均P<0.001)。COVID+患者更有可能出现心源性休克(18%),但较少接受有创血管造影(78%)(均P<0.001)。在接受血管造影的COVID+患者中,71%的患者接受了经皮冠状动脉介入治疗(PPCI),20%的接受了内科治疗(与对照组相比,P<0.001)。

COVID+患者、PUI患者和对照组患者的主要结局发生率分别为36%、13%和5%(与对照组相比,P<0.001)。

全文总结示意图

综上所述,在新冠肺炎大流行的背景下,感染新冠肺炎的STEMI患者的整体预后明显更差。COVID+STEMI患者是具有独特人口学和临床特征的高危人群,可根据该结果对特定高危人群进行重点防护。此外,PPCI仍是改善STEMI患者预后的主要再灌注方法,无论有无感染新冠肺炎。

原始出处:

Garcia Santiago,Dehghani Payam,Grines Cindy et al. Initial Findings From the North American COVID-19 Myocardial Infarction Registry. J Am Coll Cardiol, 2021, 77: 1994-2003. https://doi.org/10.1016/j.jacc.2021.02.055

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    2021-04-28 hbwxf
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    2021-04-28 gdsun
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    2021-04-28 hyf035
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    2021-04-26 烟火里的尘埃

    学习了

    0

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    2021-04-26 公卫新人

    新冠肺炎,疫情何时才能消失

    0

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    2021-04-26 jyzxjiangqin

    好文章!

    0

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