Neurology:瑞典万人研究发现,颅内感染后,癫痫发病率明显增加

2021-01-02 MedSci原创 MedSci原创

颅内感染后,癫痫发病率明显增加

 
后天性癫痫可以发生在任何脑部疾病中,国际抗癫痫联盟强调从癫痫病因学(International League Against Epilepsy, ILAE)的角度进行分类。有研究者基于1988年至2016年间发表的关于脑部感染后癫痫的文献进行了荟萃分析,估计发达国家颅内感染后,大约有8%的人会癫痫发作,在资源匮乏国家的,发病率更高。感染后的癫痫风险,因感染类型或成人、儿童不同而不同。据报道,1990-2001年和1995-2013年间,分别有24% 和46% 的疱疹性脑炎后幸存者受到癫痫的影响,1935-1981年或1982-2016年间的研究分别有27% 和32% 的脑脓肿幸存者受到癫痫的影响。在1935-1981年的细菌性脑膜炎患者中,有2% 或13% 的人患有癫痫,这取决于早期癫痫发作的情况。急性症状性发作、癫痫持续状态、 ICU 住院、脑电图异常和神经放射学损害是脑炎或脑膜炎后癫痫的危险因素。
 
瑞典哥德堡大学的Johan Zelano等人,通过回顾性研究,分析了瑞典成年人脑部感染后癫痫的危险因素和危险因素。
他们基于瑞典国家病人注册系统,在2000-2010年期间,纳入了所有年龄大于18岁但没有癫痫病史的患者,他们因为脑部感染接受了住院治疗,每个接触者有三个年龄和性别匹配的对照组(n = 12101个接触者和36228个对照者)。通过 Cox 回归分析,计算不同脑部感染后 Kaplan-Meier 癫痫发作的危险因素。随访病人直到2017年底。
 
结果显示:脑膜炎患者10年内癫痫发生率为5.9% (95% CI: 5.5-6.3) ,对照组为1.2% (95% CI: 1.0-1.4) ,蜱媒脑炎(tick borne encephalitis)患者为1.7% (95% CI: 0.7-2.7) ,细菌性脑膜炎患者为4.1% (95% CI: 3.3-4.9) ,细菌性脑膜炎患者为26.0% (95% CI: 21.5-30.5) ,脑脓肿患者为30.2% (95% CI: 27.1-33.3)。在 Cox 回归分析中,紧急入院治疗和机械通气是癫痫的危险因素。
 
这个研究的主要意义在于,成人的多种脑部感染后癫痫发作较为常见。感染的类型、严重程度和在急性期引起癫痫发作的倾向会影响后期的癫痫发作风险。

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2001186, encodeId=3749200118669, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Mon Nov 15 05:51:51 CST 2021, time=2021-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1753573, encodeId=ca4c1e535731c, content=<a href='/topic/show?id=6a57e33772b' target=_blank style='color:#2F92EE;'>#研究发现#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73377, encryptionId=6a57e33772b, topicName=研究发现)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e1736602208, createdName=hanhaisha2020, createdTime=Mon Nov 22 06:51:51 CST 2021, time=2021-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823691, encodeId=49a51823691f9, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Wed Aug 04 13:51:51 CST 2021, time=2021-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913621, encodeId=893b9136215e, content=脑部感染后,癫痫发作的机率会增加!, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Mon Jan 04 16:38:12 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579058, encodeId=ca8b15e905824, content=<a href='/topic/show?id=0a0b100408da' target=_blank style='color:#2F92EE;'>#颅内感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100408, encryptionId=0a0b100408da, topicName=颅内感染)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=00d916497138, createdName=12498768m18(暂无昵称), createdTime=Sun Jan 03 20:51:51 CST 2021, time=2021-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913305, encodeId=c4d0913305f2, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170701/IMG595791009FB761316.jpg, createdBy=abd01695121, createdName=吴教授, createdTime=Sun Jan 03 14:41:57 CST 2021, time=2021-01-03, status=1, ipAttribution=)]
    2021-11-15 yinhl1978
  2. [GetPortalCommentsPageByObjectIdResponse(id=2001186, encodeId=3749200118669, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Mon Nov 15 05:51:51 CST 2021, time=2021-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1753573, encodeId=ca4c1e535731c, content=<a href='/topic/show?id=6a57e33772b' target=_blank style='color:#2F92EE;'>#研究发现#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73377, encryptionId=6a57e33772b, topicName=研究发现)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e1736602208, createdName=hanhaisha2020, createdTime=Mon Nov 22 06:51:51 CST 2021, time=2021-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823691, encodeId=49a51823691f9, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Wed Aug 04 13:51:51 CST 2021, time=2021-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913621, encodeId=893b9136215e, content=脑部感染后,癫痫发作的机率会增加!, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Mon Jan 04 16:38:12 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579058, encodeId=ca8b15e905824, content=<a href='/topic/show?id=0a0b100408da' target=_blank style='color:#2F92EE;'>#颅内感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100408, encryptionId=0a0b100408da, topicName=颅内感染)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=00d916497138, createdName=12498768m18(暂无昵称), createdTime=Sun Jan 03 20:51:51 CST 2021, time=2021-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913305, encodeId=c4d0913305f2, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170701/IMG595791009FB761316.jpg, createdBy=abd01695121, createdName=吴教授, createdTime=Sun Jan 03 14:41:57 CST 2021, time=2021-01-03, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2001186, encodeId=3749200118669, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Mon Nov 15 05:51:51 CST 2021, time=2021-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1753573, encodeId=ca4c1e535731c, content=<a href='/topic/show?id=6a57e33772b' target=_blank style='color:#2F92EE;'>#研究发现#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73377, encryptionId=6a57e33772b, topicName=研究发现)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e1736602208, createdName=hanhaisha2020, createdTime=Mon Nov 22 06:51:51 CST 2021, time=2021-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823691, encodeId=49a51823691f9, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Wed Aug 04 13:51:51 CST 2021, time=2021-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913621, encodeId=893b9136215e, content=脑部感染后,癫痫发作的机率会增加!, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Mon Jan 04 16:38:12 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579058, encodeId=ca8b15e905824, content=<a href='/topic/show?id=0a0b100408da' target=_blank style='color:#2F92EE;'>#颅内感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100408, encryptionId=0a0b100408da, topicName=颅内感染)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=00d916497138, createdName=12498768m18(暂无昵称), createdTime=Sun Jan 03 20:51:51 CST 2021, time=2021-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913305, encodeId=c4d0913305f2, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170701/IMG595791009FB761316.jpg, createdBy=abd01695121, createdName=吴教授, createdTime=Sun Jan 03 14:41:57 CST 2021, time=2021-01-03, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=2001186, encodeId=3749200118669, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Mon Nov 15 05:51:51 CST 2021, time=2021-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1753573, encodeId=ca4c1e535731c, content=<a href='/topic/show?id=6a57e33772b' target=_blank style='color:#2F92EE;'>#研究发现#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73377, encryptionId=6a57e33772b, topicName=研究发现)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e1736602208, createdName=hanhaisha2020, createdTime=Mon Nov 22 06:51:51 CST 2021, time=2021-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823691, encodeId=49a51823691f9, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Wed Aug 04 13:51:51 CST 2021, time=2021-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913621, encodeId=893b9136215e, content=脑部感染后,癫痫发作的机率会增加!, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Mon Jan 04 16:38:12 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579058, encodeId=ca8b15e905824, content=<a href='/topic/show?id=0a0b100408da' target=_blank style='color:#2F92EE;'>#颅内感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100408, encryptionId=0a0b100408da, topicName=颅内感染)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=00d916497138, createdName=12498768m18(暂无昵称), createdTime=Sun Jan 03 20:51:51 CST 2021, time=2021-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913305, encodeId=c4d0913305f2, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170701/IMG595791009FB761316.jpg, createdBy=abd01695121, createdName=吴教授, createdTime=Sun Jan 03 14:41:57 CST 2021, time=2021-01-03, status=1, ipAttribution=)]
    2021-01-04 Jessica

    脑部感染后,癫痫发作的机率会增加!

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2001186, encodeId=3749200118669, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Mon Nov 15 05:51:51 CST 2021, time=2021-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1753573, encodeId=ca4c1e535731c, content=<a href='/topic/show?id=6a57e33772b' target=_blank style='color:#2F92EE;'>#研究发现#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73377, encryptionId=6a57e33772b, topicName=研究发现)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e1736602208, createdName=hanhaisha2020, createdTime=Mon Nov 22 06:51:51 CST 2021, time=2021-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823691, encodeId=49a51823691f9, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Wed Aug 04 13:51:51 CST 2021, time=2021-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913621, encodeId=893b9136215e, content=脑部感染后,癫痫发作的机率会增加!, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Mon Jan 04 16:38:12 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579058, encodeId=ca8b15e905824, content=<a href='/topic/show?id=0a0b100408da' target=_blank style='color:#2F92EE;'>#颅内感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100408, encryptionId=0a0b100408da, topicName=颅内感染)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=00d916497138, createdName=12498768m18(暂无昵称), createdTime=Sun Jan 03 20:51:51 CST 2021, time=2021-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913305, encodeId=c4d0913305f2, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170701/IMG595791009FB761316.jpg, createdBy=abd01695121, createdName=吴教授, createdTime=Sun Jan 03 14:41:57 CST 2021, time=2021-01-03, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=2001186, encodeId=3749200118669, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Mon Nov 15 05:51:51 CST 2021, time=2021-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1753573, encodeId=ca4c1e535731c, content=<a href='/topic/show?id=6a57e33772b' target=_blank style='color:#2F92EE;'>#研究发现#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73377, encryptionId=6a57e33772b, topicName=研究发现)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e1736602208, createdName=hanhaisha2020, createdTime=Mon Nov 22 06:51:51 CST 2021, time=2021-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823691, encodeId=49a51823691f9, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Wed Aug 04 13:51:51 CST 2021, time=2021-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913621, encodeId=893b9136215e, content=脑部感染后,癫痫发作的机率会增加!, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Mon Jan 04 16:38:12 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579058, encodeId=ca8b15e905824, content=<a href='/topic/show?id=0a0b100408da' target=_blank style='color:#2F92EE;'>#颅内感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100408, encryptionId=0a0b100408da, topicName=颅内感染)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=00d916497138, createdName=12498768m18(暂无昵称), createdTime=Sun Jan 03 20:51:51 CST 2021, time=2021-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913305, encodeId=c4d0913305f2, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170701/IMG595791009FB761316.jpg, createdBy=abd01695121, createdName=吴教授, createdTime=Sun Jan 03 14:41:57 CST 2021, time=2021-01-03, status=1, ipAttribution=)]
    2021-01-03 吴教授

    学习了

    0

相关资讯

Lancet Psychiatry:100万人的研究发现,他汀药物使用与自杀、焦虑症或癫痫发作无关

他汀类药物的使用与自杀、焦虑症或癫痫发作无关。

NEJM:孕期癫痫发作率及抗癫痫药物剂量调整

对于癫痫女性患者,孕期癫痫发作率高于围产期,但其绝对风险与一般女性患者相当,而怀孕期间,抗癫痫药物剂量的调整可能是导致发病率较高的主要因素

JNNP:扩展MOG抗体相关疾病(MOGAD)的表型:半个世纪的癫痫和复发性视神经炎

自身免疫性疾病为临床神经学中发现新的表型开辟了一个新的领域。由于自身免疫病理生理学的研究,导致了包括长期免疫抑制在内的成功的治疗策略。髓鞘少突胶质细胞糖蛋白抗体相关疾病(MOGAD)中,中枢神经系统的

JNNP:COVID-19患者癫痫样活动与癫痫发作

急性症状性癫痫在COVID-19患者中的零星病例中有报道。然而,最近一项大型回顾性队列研究表明,这些患者急性症状性癫痫发作的风险没有增加。因此,癫痫发作与COVID-19的关联性尚未确定。癫痫样活动在

JAMA Neurol:Ezogabine对ALS患者皮层和脊髓运动神经元兴奋性的影响

Ezogabine降低了ALS患者的皮层和脊髓运动神经元的兴奋性,提示这种神经生理学指标可以作为临床试验的药效学生物标志物

Neurology : 老年癫痫患者,5年后的死亡率更高

新确诊的癫痫患者和5年后的死亡率有关