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2019ASCO：阿斯利康的PARP抑制剂Lynparza，在胰腺癌III期临床中表现出色

2019-06-03 不详 MedSci原创

阿斯利康PARP抑制剂Lynparza胰腺癌Ⅲ期临床
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阿斯利康（AstraZeneca）和默克公司（Merck）在芝加哥举行的ASCO大会上发布了他们的PARP抑制剂Lynparza在胰腺癌中的新数据。

阿斯利康（AstraZeneca）和默克公司（Merck）在芝加哥举行的ASCO大会上发布了他们的PARP抑制剂Lynparza在胰腺癌中的新数据。

在携带BRCA突变晚期胰腺癌患者中进行的第3阶段POLO试验发现，Lynparza作用后患者的无进展生存期为7.4个月，几乎是安慰剂组3.8个月的两倍。

大约5％至6％的胰腺癌是由一种或两种BRCA基因突变引起的，这些基因通常与卵巢癌和乳腺癌相关，但在很多肿瘤中都能观察到。

AZ的肿瘤学研发负责人JoséBaselga表示，该公司将"尽快"向监管机构提交结果，可能为Lynparza在卵巢癌和乳腺癌之外，开辟第三个适应症。

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    2019-08-22 quxin068

    #ASC#

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    2019-08-01 jklm09

    #抑制剂#

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    2019-10-10 医生2402

    #I期临床#

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    2019-10-03 juliusluan78

    #III#

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    2019-06-05 guihongzh

    #II期临床#

    0

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    2019-06-05 智智灵药

    #III期#

    0

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    2019-06-05 lishiwen

    #PARP#

    0

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