BMJ:居住环境PM2.5暴露水平变化与心血管和呼吸系统疾病死亡风险密切相关

2021-10-21 MedSci原创 MedSci原创

PM2.5是重要的大气污染物,同时也是造成死亡及致残的重要环境因素,每年全球范围内,约400万人的死亡与较高的PM2.5水平相关。WHO指南认为,年均PM2.5水平在10 μg/m3以上,与居民

PM2.5是重要的大气污染物,同时也是造成死亡及致残的重要环境因素,每年全球范围内,约400万人的死亡与较高的PM2.5水平相关。WHO指南认为,年均PM2.5水平在10 μg/m3以上,与居民死亡风险增加相关。近日研究人员在加拿大居民中考察了PM2.5水平与额外死亡风险之间的关系。

本次研究基于加拿大1996年、2001年和2006年人口普查数据,663100名年龄在25-89岁的参与者在人口普查日前五年内一直居住同一地区,并在随后的五年内搬家。考察由于居住地变化引起的PM2.5长期暴露水平变化。研究的主要终点为自然死亡,次要终点是因心脏代谢、呼吸系统疾病和肿瘤造成的死亡。

研究发现,从高PM2.5地区搬迁到中等或低PM2.5水平地区组,居民PM2.5年暴露量分别从10.6μg/m3 下降到7.4和5.0μg/m3 。相反,从低PM2.5地区搬迁到中等或高PM2.5区域组,年PM2.5暴露水平从4.6μg/m3 增加到6.7和9.2μg/m3 。搬家五年后,PM2.5暴露量降低组居民死亡率下降了6.8%(56025人中2510人死亡vs 101960人中4925人死亡)。PM2.5暴露大幅度下降地区的人群死亡率下降幅度更大。PM2.5暴露增加组,居民死亡率增加,增加程度与PM2.5暴露增加程度相关。PM2.5暴露量的减少与心脏代谢性死亡风险减少密切相关,而PM2.5暴露量增加导致呼吸系统疾病死亡率增加,未发现强有力的证据表明PM2.5暴露与肿瘤相关死亡风险相关。

PM2.5变化对血管、呼吸系统及肿瘤疾病死亡风险的影响

在加拿大,由于居住环境变化导致的PM2.5暴露量变化会影响居民死亡风险,环境质量改善可降低居民心脏疾病死亡风险,而居住环境恶化可增加居民呼吸系统疾病死亡风险

原始出处:

Hong Chen et al. Changes in exposure to ambient fine particulate matter after relocating and long term survival in Canada: quasi-experimental study.BMJ. 08 October, 2021.

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    2022-09-17 gaoxiaoe
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  5. 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  6. 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encodeId=338f1062e465e, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=994a5643790, createdName=ms4000000654879381, createdTime=Thu Oct 21 21:53:46 CST 2021, time=2021-10-21, status=1, ipAttribution=)]
    2021-10-22 14757fdfm46暂无昵称

    谢谢分享

    0

  7. 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encodeId=338f1062e465e, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=994a5643790, createdName=ms4000000654879381, createdTime=Thu Oct 21 21:53:46 CST 2021, time=2021-10-21, status=1, ipAttribution=)]
    2021-10-22 查查佳佳

    肌肉骨骼量减少,虚弱及骨骼脆性增加,

    0

  8. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210511/e9408422a23545ef9738dd674abfc4ff/c719925083844b82986bc39d43051172.jpg, createdBy=8eb14795142, createdName=与狼共舞, createdTime=Fri Oct 22 06:15:33 CST 2021, time=2021-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1062763, encodeId=8a641062e635b, content=学了<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210926/25301c60248648b0a93bab21015a86f5/963f4290a8f24e0c884eddcf0a1cffc2.jpg, createdBy=c0e35149677, createdName=谭永娇, createdTime=Thu Oct 21 22:45:29 CST 2021, time=2021-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1062746, encodeId=338f1062e465e, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=994a5643790, createdName=ms4000000654879381, createdTime=Thu Oct 21 21:53:46 CST 2021, time=2021-10-21, status=1, ipAttribution=)]
    2021-10-22 与狼共舞

    学习学习

    0

  9. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c01c5209406, createdName=14757fdfm46暂无昵称, createdTime=Fri Oct 22 13:50:08 CST 2021, time=2021-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1062820, encodeId=0ddc1062820c7, content=肌肉骨骼量减少,虚弱及骨骼脆性增加,, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Fri Oct 22 07:34:32 CST 2021, time=2021-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1062809, encodeId=eca910628098d, content=学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, 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encodeId=338f1062e465e, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=994a5643790, createdName=ms4000000654879381, createdTime=Thu Oct 21 21:53:46 CST 2021, time=2021-10-21, status=1, ipAttribution=)]
    2021-10-21 谭永娇

    学了#学习#

    0

  10. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c01c5209406, createdName=14757fdfm46暂无昵称, createdTime=Fri Oct 22 13:50:08 CST 2021, time=2021-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1062820, encodeId=0ddc1062820c7, content=肌肉骨骼量减少,虚弱及骨骼脆性增加,, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Fri Oct 22 07:34:32 CST 2021, time=2021-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1062809, encodeId=eca910628098d, content=学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, 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encodeId=338f1062e465e, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=994a5643790, createdName=ms4000000654879381, createdTime=Thu Oct 21 21:53:46 CST 2021, time=2021-10-21, status=1, ipAttribution=)]
    2021-10-21 ms4000000654879381

    谢谢分享

    0

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