Medicine (Baltimore):来福林 vs. 莫西沙星治疗社区获得性细菌性肺炎患者的临床疗效和耐受性

2020-12-04 MedSci原创 MedSci原创

来福林是一种新型胸腺素抗生素,对大部分社区获得性细菌性肺炎(CABP)病原体具有强大的体外活性。然而,来氟米林治疗CABP的临床疗效和安全性仍不清楚。2项III期试验对研究来氟米林与莫西沙星治疗CAB

来福林是一种新型胸腺素抗生素,对大部分社区获得性细菌性肺炎(CABP)病原体具有强大的体外活性。然而,来氟米林治疗CABP的临床疗效和安全性仍不清楚。2项III期试验对研究来氟米林与莫西沙星治疗CABP的临床疗效和安全性的进行了综合分析,研究结果已在线发表于Medicine (Baltimore)

研究共纳入1289例患者(来氟米林组:646例,莫西沙星组:643例)。结果显示,来福林组和莫西沙星组的早期临床反应率分别为89.3%和90.5%。来福林不劣于莫西沙星(89.3% vs 90.5%,RR:0.99,95% CI:0.95-1.02,I = 0%)。在治愈时的临床反应方面,来福林组和莫西沙星组之间无显著差异(改良后的意向治疗人群,RR:0.98,95% CI:0.94-1.02,I = 0%;临床可评价人群,RR:0.96,95% CI:0.93-1.00,I = 0%)。在亚组分析中,在不同亚组人群和所有基线CABP病原体中,来福林早期临床评估时的临床反应率和试验治愈时的临床反应率与莫西沙星相似。此外,来福林与莫西沙星的不良事件风险相似。

综上所述,该研究结果表明,来福林治疗CABP的临床疗效和耐受性与莫西沙星相似。

 

原始出处:

 

Hung-Jen Tang , Jui-Hsiang Wang, Chih-Cheng Lai. Lefamulin vs moxifloxacin for community-acquired bacterial pneumonia. Medicine (Baltimore) . 2020 Jul 17;99(29):e21223. doi: 10.1097/MD.0000000000021223.

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    2021-05-23 jeanqiuqiu
  2. 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    2020-12-04 Psycho.Dr Du

    只听说过来福灵,是用来杀虫的,莫非此林即彼灵?#抗生素#🤣🤣

    1

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objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22897, encryptionId=acc02289e40, topicName=临床疗效)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8346212, createdName=respect, createdTime=Sun Mar 21 05:41:31 CST 2021, time=2021-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=925119, encodeId=a93d92511988, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01432550878, createdName=12540703m99暂无昵称, createdTime=Wed Feb 17 20:19:40 CST 2021, time=2021-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1861412, encodeId=fe2c186141271, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Mon May 17 19:41:31 CST 2021, time=2021-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=922673, encodeId=07739226e370, content=👌, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201207/c90e91ef40764236aed29bf0de055c37/23caad74c24d4fc2b36ce99b11a0323d.jpg, createdBy=dbd41665725, createdName=哈!, createdTime=Thu Feb 04 06:11:55 CST 2021, time=2021-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=915077, encodeId=4d479150e7b0, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59321624668, createdName=zb1235672, createdTime=Sat Jan 09 22:15:02 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=906880, encodeId=92659068809f, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201207/c90e91ef40764236aed29bf0de055c37/23caad74c24d4fc2b36ce99b11a0323d.jpg, createdBy=dbd41665725, createdName=哈!, createdTime=Thu Dec 10 22:31:25 CST 2020, time=2020-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773896, encodeId=5c1a1e7389626, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Sun Aug 29 16:41:31 CST 2021, time=2021-08-29, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1859088, encodeId=d5151859088aa, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Sun May 23 22:41:31 CST 2021, time=2021-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=904791, encodeId=f451904e9150, content=只听说过来福灵,是用来杀虫的,莫非此林即彼灵?<a href='/topic/show?id=f5f955419b0' target=_blank style='color:#2F92EE;'>#抗生素#</a>🤣🤣, beContent=null, objectType=article, channel=null, level=null, likeNumber=159, replyNumber=1, topicName=null, topicId=null, topicList=[TopicDto(id=55419, encryptionId=f5f955419b0, topicName=抗生素)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210607/9f00a0de660e4b36b77a9a5f7620d6bf/98c22b17ddf7446fa7b9a618fabcb9f7.jpg, createdBy=a8fb2299762, createdName=Psycho.Dr Du, createdTime=Fri Dec 04 10:35:48 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2042675, encodeId=849420426e5fd, content=<a href='/topic/show?id=999c88014ea' target=_blank style='color:#2F92EE;'>#获得性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88014, encryptionId=999c88014ea, topicName=获得性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d4b7363, createdName=pandamao2010, createdTime=Fri Jul 23 20:41:31 CST 2021, time=2021-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1907206, encodeId=c605190e206b9, content=<a href='/topic/show?id=acc02289e40' target=_blank style='color:#2F92EE;'>#临床疗效#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22897, encryptionId=acc02289e40, topicName=临床疗效)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8346212, createdName=respect, createdTime=Sun Mar 21 05:41:31 CST 2021, time=2021-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=925119, encodeId=a93d92511988, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01432550878, createdName=12540703m99暂无昵称, createdTime=Wed Feb 17 20:19:40 CST 2021, time=2021-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1861412, encodeId=fe2c186141271, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Mon May 17 19:41:31 CST 2021, time=2021-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=922673, encodeId=07739226e370, content=👌, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201207/c90e91ef40764236aed29bf0de055c37/23caad74c24d4fc2b36ce99b11a0323d.jpg, createdBy=dbd41665725, createdName=哈!, createdTime=Thu Feb 04 06:11:55 CST 2021, time=2021-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=915077, encodeId=4d479150e7b0, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59321624668, createdName=zb1235672, createdTime=Sat Jan 09 22:15:02 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=906880, encodeId=92659068809f, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201207/c90e91ef40764236aed29bf0de055c37/23caad74c24d4fc2b36ce99b11a0323d.jpg, createdBy=dbd41665725, createdName=哈!, createdTime=Thu Dec 10 22:31:25 CST 2020, time=2020-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773896, encodeId=5c1a1e7389626, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Sun Aug 29 16:41:31 CST 2021, time=2021-08-29, status=1, ipAttribution=)]
    2021-02-17 12540703m99暂无昵称

    学习

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1859088, encodeId=d5151859088aa, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Sun May 23 22:41:31 CST 2021, time=2021-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=904791, encodeId=f451904e9150, content=只听说过来福灵,是用来杀虫的,莫非此林即彼灵?<a href='/topic/show?id=f5f955419b0' target=_blank style='color:#2F92EE;'>#抗生素#</a>🤣🤣, beContent=null, objectType=article, channel=null, level=null, likeNumber=159, replyNumber=1, topicName=null, topicId=null, topicList=[TopicDto(id=55419, encryptionId=f5f955419b0, topicName=抗生素)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210607/9f00a0de660e4b36b77a9a5f7620d6bf/98c22b17ddf7446fa7b9a618fabcb9f7.jpg, createdBy=a8fb2299762, createdName=Psycho.Dr Du, createdTime=Fri Dec 04 10:35:48 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2042675, encodeId=849420426e5fd, content=<a href='/topic/show?id=999c88014ea' target=_blank style='color:#2F92EE;'>#获得性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88014, encryptionId=999c88014ea, topicName=获得性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d4b7363, createdName=pandamao2010, createdTime=Fri Jul 23 20:41:31 CST 2021, time=2021-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1907206, encodeId=c605190e206b9, content=<a href='/topic/show?id=acc02289e40' target=_blank style='color:#2F92EE;'>#临床疗效#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22897, encryptionId=acc02289e40, topicName=临床疗效)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8346212, createdName=respect, createdTime=Sun Mar 21 05:41:31 CST 2021, time=2021-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=925119, encodeId=a93d92511988, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01432550878, createdName=12540703m99暂无昵称, createdTime=Wed Feb 17 20:19:40 CST 2021, time=2021-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1861412, encodeId=fe2c186141271, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Mon May 17 19:41:31 CST 2021, time=2021-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=922673, encodeId=07739226e370, content=👌, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201207/c90e91ef40764236aed29bf0de055c37/23caad74c24d4fc2b36ce99b11a0323d.jpg, createdBy=dbd41665725, createdName=哈!, createdTime=Thu Feb 04 06:11:55 CST 2021, time=2021-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=915077, encodeId=4d479150e7b0, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59321624668, createdName=zb1235672, createdTime=Sat Jan 09 22:15:02 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=906880, encodeId=92659068809f, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201207/c90e91ef40764236aed29bf0de055c37/23caad74c24d4fc2b36ce99b11a0323d.jpg, createdBy=dbd41665725, createdName=哈!, createdTime=Thu Dec 10 22:31:25 CST 2020, time=2020-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773896, encodeId=5c1a1e7389626, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Sun Aug 29 16:41:31 CST 2021, time=2021-08-29, status=1, ipAttribution=)]
    2021-05-17 shizhenshan
  7. [GetPortalCommentsPageByObjectIdResponse(id=1859088, encodeId=d5151859088aa, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Sun May 23 22:41:31 CST 2021, time=2021-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=904791, encodeId=f451904e9150, content=只听说过来福灵,是用来杀虫的,莫非此林即彼灵?<a href='/topic/show?id=f5f955419b0' target=_blank style='color:#2F92EE;'>#抗生素#</a>🤣🤣, beContent=null, objectType=article, channel=null, level=null, likeNumber=159, replyNumber=1, topicName=null, topicId=null, topicList=[TopicDto(id=55419, encryptionId=f5f955419b0, topicName=抗生素)], attachment=null, authenticateStatus=null, 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objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22897, encryptionId=acc02289e40, topicName=临床疗效)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8346212, createdName=respect, createdTime=Sun Mar 21 05:41:31 CST 2021, time=2021-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=925119, encodeId=a93d92511988, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01432550878, createdName=12540703m99暂无昵称, createdTime=Wed Feb 17 20:19:40 CST 2021, time=2021-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1861412, encodeId=fe2c186141271, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Mon May 17 19:41:31 CST 2021, time=2021-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=922673, encodeId=07739226e370, content=👌, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201207/c90e91ef40764236aed29bf0de055c37/23caad74c24d4fc2b36ce99b11a0323d.jpg, createdBy=dbd41665725, createdName=哈!, createdTime=Thu Feb 04 06:11:55 CST 2021, time=2021-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=915077, encodeId=4d479150e7b0, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59321624668, createdName=zb1235672, createdTime=Sat Jan 09 22:15:02 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=906880, encodeId=92659068809f, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201207/c90e91ef40764236aed29bf0de055c37/23caad74c24d4fc2b36ce99b11a0323d.jpg, createdBy=dbd41665725, createdName=哈!, createdTime=Thu Dec 10 22:31:25 CST 2020, time=2020-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773896, encodeId=5c1a1e7389626, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Sun Aug 29 16:41:31 CST 2021, time=2021-08-29, status=1, ipAttribution=)]
    2021-02-04 哈!

    👌

    0

  8. 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    2021-01-09 zb1235672

    学习了

    0

  9. 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level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Mon May 17 19:41:31 CST 2021, time=2021-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=922673, encodeId=07739226e370, content=👌, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201207/c90e91ef40764236aed29bf0de055c37/23caad74c24d4fc2b36ce99b11a0323d.jpg, createdBy=dbd41665725, createdName=哈!, createdTime=Thu Feb 04 06:11:55 CST 2021, time=2021-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=915077, encodeId=4d479150e7b0, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59321624668, createdName=zb1235672, createdTime=Sat Jan 09 22:15:02 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=906880, encodeId=92659068809f, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201207/c90e91ef40764236aed29bf0de055c37/23caad74c24d4fc2b36ce99b11a0323d.jpg, createdBy=dbd41665725, createdName=哈!, createdTime=Thu Dec 10 22:31:25 CST 2020, time=2020-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773896, encodeId=5c1a1e7389626, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, 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    2020-12-10 哈!

    0

  10. 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    2021-08-29 kalseyzl

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